Gene detail

Detailed information of ENSBQFP00000011015.1 in Heliopora coerulea

Genomic Location: JASJOG010000023.1:2398017...2428606
NR annotation: XP_028401842.1, uncharacterized protein LOC114524844 [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSBQFT00000012217

ATGGCAATATTCCACGTATTTTTCCTCGTCGTTTTTGTCGTCCACTCCACTTATGCGCTAACATGCACTTCGTGTGAGGAAGCTCTTTGCGTGAAACCAGTCAACTGTAAAGGTGGTGTAGTGAAAGGTGTATGCGGGTGTTGCGACGTTTGTGCCAAGATACAAAATGAACGTTGTGGAGGTCCGTGGCTTCTACATGGTCGGTGCGCCAAGGGACTGAAGTGCGTCTCAAGAACCCGCATGAAAAATGAGAATGGCTTTCTTCccaaatattttcaaactgGCGTTTGTGAGCCTGATGCTTGTGAAGCGAAAACATGCGGATTCCGAGAGAAGTGCAAGGTCAACAAACGGGGAAAGCTTATGTGTTTTTGTCCCAGAAAATGTAGAAAAAGGCGCCAACCAGTTTGTGGCCTGCTCAACGGGAAGGAATATCGAAACAAATGTGAGCTTACTCGAGAGGAATGCCTTACTAAGAAAGAAATAGGCTTTGTTGTAGGATCGTGCAAAAAATGTACATTCAAAGGAAAGGAATACAAGTTTGGTGATACAAGACCAGACGTTAAGCCATGCGAAGTTTGCGTTTGCCACCATAGTTCATGGAAATGCCACATGAAACAAAACTGTTCTACGAACAACGTATCCAAGGCTACCAATAAACAATATTCATGCCTGATATCGCCCGACGGTGACATTGTGCTGCCATGTCCGAAAAGTTTCTCCTGTAAAGTCATGCCTACCGCTAAGAAATTGGTAATTGATCACATTGGAATGTGCAGAGAGGGAGTGTGCAAGAAGAAAAACAAGTGCAAATATAAAAGACAAAGATACAATTCTGGAGAGTCAAGATCATCTGATAAGCCGTGTGAGATTTGCATTTGCCAATCTAGCTCATGGAAATGTCGCGAGAAACAAAACTGTCATGCTTGCGCGAAAACACATCGTTGGTATGGTGAGTGGTTTGAACGTTGTCCTCAGGGCTTTTCTTGTGAATTATCTCATTCTTTCAAGAAGCTACGCGTGTTCCGTGCTGGACTTTTCACACAGGGAGAATGCAAGAAGAAAAATGAATTTCAAGCAGGGACTAAAACGTATTCCATTCACCCGAGCACTGGTTTCGTATCAACAGTAAAACCATCAGTGAAAGGATTACAGATAAAACAACTAAAAGGAGTCATGGTACATGTCTGCATGGCTAAGGCTGACACGGGGACGTGTAGACCAGCGACGTTAATCCGTTGGTTCTATAATGCGAGCAGCCAAACCTGTGAGCAATTCCCATATAGTGGATGTGGTGGAAACTTTAACAACTTCCTCTCAAAGAAAAACTGTGTTGACATTTGCTGTTCAGATATGCATCGTCGTCAGTGGCAATCTACACCCACAACTCAGTCATCTCAACTACATATGACCACGAAGATGGTTGCGTCACACAAGGGAGACATACTTATGGAGATGTGTCACGACATAAAGACTGGGATGTCATACCGGGATGGAGAAAAATGGAATGTGGACGAATGCACATCATGCACTTGTGTCAGTGGCCGTGCTTTGTGTATCGCAGCAAGGTGTCACGTGTCTTGTTCAAGACCGATCCACATCAAAGGAAAATGCTGCCCAGTTTGTGAATCAGACTTAGAACATTCAGGGAAAGCCGTCGACAATAAAGAAACAAGTTGCAAAGATACCAAATCAGGTTTGTGGTATCACTCTGGCGAAAGCTGGAACAGGAGCGAGTGTGTCCTTTGTATTTGTTTCGACGGTGAAATTTCGTGTATGTCATCAATCTGTACCAAGCCACTGTGCAAACATCCAGCCAAGAAAGACGGCGTTTGTTGTCCATATTGCCCTGAAGACGAACGCCAAGTTCCACAACCGACAGCAGCAGTGAGCCCGAGATGCAAGGATGAGGGAAGCGGTCAATATTACTCACCTGGAGAAGCTTGGCGAGTCAGTGATTGTGTCAGCTGTTTCTGTGGTAACGATGGTCAAAATGTTTGTCATGAATTGACATGTCTTAAGTCAAAATGCGAAAATCCAGTTCATTTGCAAGGAAGATGCTGCCCAGTTTGTCCAGAATCATTCCTCTCAGCCTGTACCTACGACAACCACCAGTATTTTCAAGGAGATTTTATGCTTTTGGGAGACATGTGCACACTTTGtaAGTGCAATGGTAACGCATGGAACTGCACCAAGAAGCATTGCAACGAAACAGTAAACGGGATTAATTCCATactcaaatttgaaaatgagaAGGCCAATAACAATATGCAAGATCCCAGTTCAATATCGAACATACCCGAAACGCCTGGTGTGAGCTTGGACGACTTTAGTAGTGAAGATAACGATGAGTTTATTGTAGAGGACCCAATGAGAATGACAAGACGAAGTACCCAGCGACCAGTTCTACAAAGCACAAAGCATAGCACCACAGCCACTTCAAGTAATCATAAGGTCTCTGCAACATCCTTGAGGAGTCCTAAGATTGATGTAAGCGATGCAGTTGAAGTATTATCCCAAGCAAGTTCAGGTACAAATGATGTACAGAAGAAACCTCGCATGATAACAAGAGATGATCCAGGCTCCAACCCGGAAAGGCAACCATTGCTTAAAGACTACGAAAATAGAATGTGGTCCTCGGATTTTAAGGGATATGTCCATCCTTATCCCGGAAAAGAGAACCATACTAAGGTTTACCGCACAAAATTGTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q7T3Q2	Cysteine-rich motor neuron 1 protein OS=Danio rerio OX=7955 GN=crim1 PE=2 SV=1
Q8AWW5	Cysteine-rich motor neuron 1 protein OS=Gallus gallus OX=9031 GN=CRIM1 PE=2 SV=1
Q9JLL0	Cysteine-rich motor neuron 1 protein OS=Mus musculus OX=10090 GN=Crim1 PE=2 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000757 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00014 all species →	Kunitz_BPTI	Kunitz/Bovine pancreatic trypsin inhibitor domain	Domain	Interproscan
PF00219 all species →	IGFBP	Insulin-like growth factor binding protein	Domain	Interproscan
PF00093 all species →	VWC	von Willebrand factor type C domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002350 all species →	Domain	Kazal domain	Interproscan
IPR002223 all species →	Domain	Pancreatic trypsin inhibitor Kunitz domain	Interproscan
IPR001007 all species →	Domain	VWFC domain	Interproscan
IPR000867 all species →	Domain	Insulin-like growth factor-binding protein, IGFBP	Interproscan
IPR036058 all species →	Homologous_superfamily	Kazal domain superfamily	Interproscan
IPR009030 all species →	Homologous_superfamily	Growth factor receptor cysteine-rich domain superfamily	Interproscan
IPR036880 all species →	Homologous_superfamily	Pancreatic trypsin inhibitor Kunitz domain superfamily	Interproscan
IPR052624 all species →	Family	Cysteine-rich motor neuron 1	Interproscan
IPR020901 all species →	Conserved_site	Proteinase inhibitor I2, Kunitz, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46439 all species →	CYSTEINE-RICH MOTOR NEURON 1 PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004867 all species →	Molecular Function	serine-type endopeptidase inhibitor activity	Interproscan
GO:0005576 all species →	Cellular Component	extracellular region	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSBQFP00000011015.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000011015.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples

36TPM > 0

6Conditions

242.9Max TPM

144.2Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole coral	17	17	174.06	242.67
polyp and skeleton · 31C, 3week	6	6	130.78	242.85
polyp and skeleton · 28C, 3week	6	5	109.92	160.71
polyp and skeleton · 26C, 3week	4	4	111.73	125.49
polyp and skeleton · 28C, 24hr	2	2	150.97	159.90
polyp and skeleton · 31C, 24hr	2	2	92.43	99.98

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
ERR6178778	Whole coral	Whole coral	not recorded	not recorded	ERP120267	242.67
ERR6178773	Whole coral	Whole coral	not recorded	not recorded	ERP120267	236.40
ERR6178389	Whole coral	Whole coral	not recorded	not recorded	ERP120267	196.17
ERR6178782	Whole coral	Whole coral	not recorded	not recorded	ERP120267	192.97
ERR6178387	Whole coral	Whole coral	not recorded	not recorded	ERP120267	192.23
ERR6178779	Whole coral	Whole coral	not recorded	not recorded	ERP120267	188.98
ERR6178775	Whole coral	Whole coral	not recorded	not recorded	ERP120267	185.74
ERR6178776	Whole coral	Whole coral	not recorded	not recorded	ERP120267	180.03
ERR6178772	Whole coral	Whole coral	not recorded	not recorded	ERP120267	174.41
ERR6178770	Whole coral	Whole coral	not recorded	not recorded	ERP120267	172.46
ERR6178388	Whole coral	Whole coral	not recorded	not recorded	ERP120267	167.76
ERR6178774	Whole coral	Whole coral	not recorded	not recorded	ERP120267	164.78
ERR6178780	Whole coral	Whole coral	not recorded	not recorded	ERP120267	161.90
ERR6178777	Whole coral	Whole coral	not recorded	not recorded	ERP120267	157.59
ERR6178771	Whole coral	Whole coral	not recorded	not recorded	ERP120267	132.92
ERR6178783	Whole coral	Whole coral	not recorded	not recorded	ERP120267	126.67
ERR6178781	Whole coral	Whole coral	not recorded	not recorded	ERP120267	85.40
SRR12587804	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	242.85
SRR12578065	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	222.68
SRR12578068	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	114.10
SRR12578066	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	83.10
SRR12587800	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	68.81
SRR12587799	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	53.15
SRR5949849	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	160.71
SRR12587803	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	156.05
SRR12587802	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	145.43
SRR12587808	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	133.67
SRR12587807	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	63.64
SRR12578067	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	0.00
SRR12587801	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	125.49
SRR12587806	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	118.25
SRR12587805	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	103.12
SRR12587798	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	100.06
SRR5949850	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	159.90
SRR12578063	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	142.04
SRR5949848	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	99.98
SRR12578064	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	84.88

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	1	ENSBQFP00000009797	0.744314504165161
Negatively correlated	14	ENSBQFP00000001999	-0.713495390119602

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000011015, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →