Detailed information of ENSBQFP00000011449.1 in Heliopora coerulea

Genomic Location: JASJOG010000011.1:2422655...2427281
NR annotation: XP_028391811.1, autophagy-related protein 8-like [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P60519Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Bos taurus OX=9913 GN=GABARAPL2 PE=1 SV=1
P60520Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1
P60521Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Mus musculus OX=10090 GN=Gabarapl2 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001129 (this species only) · gene tree & orthology
Ubiquitin familyULD|UBL|ATG8 · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02991
all species →
ATG8Autophagy protein Atg8 ubiquitin likeDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR004241
all species →
FamilyAutophagy protein Atg8 ubiquitin-likeInterproscan
IPR029071
all species →
Homologous_superfamilyUbiquitin-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10969
all species →
MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000045
all species →
Biological Processautophagosome assemblyInterproscan
GO:0000421
all species →
Cellular Componentautophagosome membraneInterproscan
GO:0000422
all species →
Biological Processautophagy of mitochondrionInterproscan
GO:0005776
all species →
Cellular ComponentautophagosomeInterproscan
GO:0005829
all species →
Cellular ComponentcytosolInterproscan
GO:0006995
all species →
Biological Processcellular response to nitrogen starvationInterproscan
GO:0016236
all species →
Biological ProcessmacroautophagyInterproscan
GO:0031625
all species →
Molecular Functionubiquitin protein ligase bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K08341GABARAP, ATG8, LC3; GABA(A) receptor-associated protein-Mitochondrial biogenesisko03029deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000011449.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
37TPM > 0
6Conditions
493.7Max TPM
277.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 289.38 377.22
polyp and skeleton · 31C, 3week 6 6 282.12 356.20
polyp and skeleton · 28C, 3week 6 6 287.31 493.69
polyp and skeleton · 26C, 3week 4 4 258.52 364.40
polyp and skeleton · 28C, 24hr 2 2 235.11 272.59
polyp and skeleton · 31C, 24hr 2 2 204.96 222.11

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 377.22
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 345.89
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 333.45
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 314.89
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 297.42
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 295.47
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 292.65
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 287.85
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 284.54
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 282.17
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 281.76
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 270.80
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 265.76
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 256.37
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 249.10
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 243.48
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 240.65
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 356.20
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 318.62
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 314.18
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 283.97
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 281.74
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 138.00
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 493.69
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 306.32
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 293.71
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 251.57
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 211.62
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 166.91
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 364.40
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 241.33
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 233.69
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 194.66
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 272.59
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 197.62
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 222.11
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 187.80

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated5ENSBQFP000000241360.738011777446681
Negatively correlated30ENSBQFP00000026573-0.671609551526932

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000011449, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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