Gene detail

Detailed information of ENSBQFP00000012338.1 in Heliopora coerulea

Genomic Location: JASJOG010000011.1:541740...547597
NR annotation: XP_028410164.1, eukaryotic translation initiation factor 6-like [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6GR45	Eukaryotic translation initiation factor 6 OS=Xenopus laevis OX=8355 GN=eif6 PE=2 SV=1
O55135	Eukaryotic translation initiation factor 6 OS=Mus musculus OX=10090 GN=Eif6 PE=1 SV=2
P56537	Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0008106 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01912 all species →	eIF-6	eIF-6 family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002769 all species →	Family	Translation initiation factor IF6	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10784 all species →	EUKARYOTIC TRANSLATION INITIATION FACTOR 6	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0042256 all species →	Biological Process	cytosolic ribosome assembly	Interproscan
GO:0043022 all species →	Molecular Function	ribosome binding	Interproscan
GO:0000054 all species →	Biological Process	ribosomal subunit export from nucleus	Interproscan
GO:0000460 all species →	Biological Process	maturation of 5.8S rRNA	Interproscan
GO:0000470 all species →	Biological Process	maturation of LSU-rRNA	Interproscan
GO:0005730 all species →	Cellular Component	nucleolus	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0030687 all species →	Cellular Component	preribosome, large subunit precursor	Interproscan
GO:0043023 all species →	Molecular Function	ribosomal large subunit binding	Interproscan
GO:1902626 all species →	Biological Process	assembly of large subunit precursor of preribosome	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K03264	EIF6; translation initiation factor 6	-	Translation factors	ko03012	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000012338.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples

33TPM > 0

6Conditions

145.8Max TPM

85.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole coral	17	17	71.02	91.65
polyp and skeleton · 31C, 3week	6	6	115.05	135.35
polyp and skeleton · 28C, 3week	6	4	89.93	144.33
polyp and skeleton · 26C, 3week	4	2	66.50	134.73
polyp and skeleton · 28C, 24hr	2	2	98.62	107.71
polyp and skeleton · 31C, 24hr	2	2	127.70	145.83

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
ERR6178387	Whole coral	Whole coral	not recorded	not recorded	ERP120267	91.65
ERR6178780	Whole coral	Whole coral	not recorded	not recorded	ERP120267	88.12
ERR6178388	Whole coral	Whole coral	not recorded	not recorded	ERP120267	87.66
ERR6178781	Whole coral	Whole coral	not recorded	not recorded	ERP120267	78.84
ERR6178782	Whole coral	Whole coral	not recorded	not recorded	ERP120267	77.89
ERR6178770	Whole coral	Whole coral	not recorded	not recorded	ERP120267	76.60
ERR6178771	Whole coral	Whole coral	not recorded	not recorded	ERP120267	74.52
ERR6178777	Whole coral	Whole coral	not recorded	not recorded	ERP120267	74.13
ERR6178779	Whole coral	Whole coral	not recorded	not recorded	ERP120267	73.47
ERR6178783	Whole coral	Whole coral	not recorded	not recorded	ERP120267	73.33
ERR6178772	Whole coral	Whole coral	not recorded	not recorded	ERP120267	70.21
ERR6178389	Whole coral	Whole coral	not recorded	not recorded	ERP120267	62.92
ERR6178776	Whole coral	Whole coral	not recorded	not recorded	ERP120267	59.93
ERR6178773	Whole coral	Whole coral	not recorded	not recorded	ERP120267	57.71
ERR6178778	Whole coral	Whole coral	not recorded	not recorded	ERP120267	55.54
ERR6178775	Whole coral	Whole coral	not recorded	not recorded	ERP120267	54.73
ERR6178774	Whole coral	Whole coral	not recorded	not recorded	ERP120267	50.13
SRR12578066	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	135.35
SRR12587800	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	125.71
SRR12587799	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	117.16
SRR12587804	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	115.93
SRR12578065	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	110.78
SRR12578068	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	85.38
SRR12587807	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	144.33
SRR12587802	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	140.39
SRR12587808	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	129.09
SRR12587803	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	125.78
SRR12578067	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	0.00
SRR5949849	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	0.00
SRR12587798	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	134.73
SRR12587805	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	131.28
SRR12587801	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	0.00
SRR12587806	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	0.00
SRR12578063	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	107.71
SRR5949850	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	89.53
SRR12578064	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	145.83
SRR5949848	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	109.57

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	10	ENSBQFP00000038343	0.839197080047147
Negatively correlated	28	ENSBQFP00000007795	-0.78668424973549

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000012338, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →