Detailed information of ENSBQFP00000012995 in Heliopora coerulea

Genomic Location: JASJOG010000015.1:2176808...2187310
NR annotation: CAB3979974.1, Hypothetical predicted protein [Paramuricea clavata]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P35611Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2
Q5RA10Alpha-adducin OS=Pongo abelii OX=9601 GN=ADD1 PE=2 SV=1
Q9QYC0Alpha-adducin OS=Mus musculus OX=10090 GN=Add1 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002450 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00596
all species →		Aldolase_IIClass II Aldolase and Adducin N-terminal domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR001303
all species →		DomainClass II aldolase/adducin N-terminalInterproscan
IPR051017
all species →		FamilyAldolase class II Adducin subfamilyInterproscan
IPR036409
all species →		Homologous_superfamilyClass II aldolase/adducin N-terminal domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10672
all species →		ADDUCINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005856
all species →		Cellular ComponentcytoskeletonInterproscan
GO:0005886
all species →		Cellular Componentplasma membraneInterproscan
GO:0014069
all species →		Cellular Componentpostsynaptic densityInterproscan
GO:0051015
all species →		Molecular Functionactin filament bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K18622ADD; adducin-Cytoskeleton proteinsko04812deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000012995 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
37TPM > 0
6Conditions
904.1Max TPM
354.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 326.28 548.49
polyp and skeleton · 31C, 3week 6 6 358.68 482.79
polyp and skeleton · 28C, 3week 6 6 480.47 904.08
polyp and skeleton · 26C, 3week 4 4 287.34 382.63
polyp and skeleton · 28C, 24hr 2 2 307.39 335.55
polyp and skeleton · 31C, 24hr 2 2 381.67 489.16

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 548.49
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 478.92
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 470.73
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 426.87
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 404.96
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 399.67
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 359.38
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 345.48
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 342.64
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 317.67
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 271.49
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 257.35
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 256.08
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 246.14
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 231.02
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 101.27
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 88.68
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 482.79
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 461.84
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 361.84
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 343.40
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 281.51
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 220.73
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 904.08
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 508.08
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 454.07
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 445.76
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 292.88
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 277.97
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 382.63
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 351.70
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 237.32
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 177.70
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 335.55
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 279.23
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 489.16
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 274.19

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated3ENSBQFP000000204060.755436136914353
Negatively correlated585ENSBQFP00000009190-0.601972053745066

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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