Detailed information of ENSBQFP00000013846.1 in Heliopora coerulea

Genomic Location: JASJOG010000025.1:1870053...1991335
NR annotation: XP_028416443.1, myotubularin-related protein 13-like [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q6ZPE2Myotubularin-related protein 5 OS=Mus musculus OX=10090 GN=Sbf1 PE=1 SV=2
O95248Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4
Q86WG5Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002736 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF03456
all species →		uDENNuDENN domainDomainInterproscan
PF00130
all species →		C1_1Phorbol esters/diacylglycerol binding domain (C1 domain)DomainInterproscan
PF02141
all species →		DENNDENN (AEX-3) domainFamilyInterproscan
PF02893
all species →		GRAMGRAM domainDomainInterproscan
PF12335
all species →		SBF2Myotubularin protein FamilyInterproscan
PF00169
all species →		PHPH domainDomainInterproscan
PF06602
all species →		Myotub-relatedMyotubularin-like phosphatase domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR005113
all species →		DomainuDENN domainInterproscan
IPR046349
all species →		Homologous_superfamilyC1-like domain superfamilyInterproscan
IPR037516
all species →		DomainTripartite DENN domainInterproscan
IPR002219
all species →		DomainProtein kinase C-like, phorbol ester/diacylglycerol-binding domainInterproscan
IPR001194
all species →		DomaincDENN domainInterproscan
IPR004182
all species →		DomainGRAM domainInterproscan
IPR011993
all species →		Homologous_superfamilyPH-like domain superfamilyInterproscan
IPR030564
all species →		FamilyMyotubularin familyInterproscan
IPR022096
all species →		DomainSBF1/SBF2 domainInterproscan
IPR029021
all species →		Homologous_superfamilyProtein-tyrosine phosphatase-likeInterproscan
IPR001849
all species →		DomainPleckstrin homology domainInterproscan
IPR005112
all species →		DomaindDENN domainInterproscan
IPR010569
all species →		DomainMyotubularin-like, phosphatase domainInterproscan
IPR043153
all species →		Homologous_superfamilyDENN domain, C-terminal lobeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10807
all species →		MYOTUBULARIN-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005085
all species →		Molecular Functionguanyl-nucleotide exchange factor activityInterproscan
GO:0005737
all species →		Cellular ComponentcytoplasmInterproscan
GO:0016020
all species →		Cellular ComponentmembraneInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K18061SBF1_2, MTMR5_13; myotubularin-related protein 5/13-Protein phosphatases and associated proteinsko01009deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000013846.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
35TPM > 0
6Conditions
90.4Max TPM
29.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 29.54 47.64
polyp and skeleton · 31C, 3week 6 6 25.37 36.06
polyp and skeleton · 28C, 3week 6 5 34.78 90.40
polyp and skeleton · 26C, 3week 4 4 35.18 46.50
polyp and skeleton · 28C, 24hr 2 2 31.46 33.57
polyp and skeleton · 31C, 24hr 2 1 9.62 19.24

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 47.64
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 37.89
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 33.88
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 33.23
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 33.02
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 32.43
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 32.11
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 31.64
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 27.96
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 27.90
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 26.29
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 26.24
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 25.01
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 24.44
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 23.47
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 20.35
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 18.64
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 36.06
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 28.47
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 27.11
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 25.40
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 20.53
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 14.65
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 90.40
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 33.80
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 31.18
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 26.69
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 26.60
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 46.50
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 35.89
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 30.88
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 27.45
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 33.57
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 29.35
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 19.24
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 0.00

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated18ENSBQFP000000492750.874681072133928
Negatively correlated18ENSBQFP00000045679-0.68540175328263

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000013846, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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