Detailed information of ENSBQFP00000018754 in Heliopora coerulea

Genomic Location: JASJOG010000050.1:250029...328297
NR annotation: XP_028401862.1, mitochondrial import receptor subunit TOM70-like [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O94826Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1
Q75Q39Mitochondrial import receptor subunit TOM70 OS=Rattus norvegicus OX=10116 GN=Tomm70 PE=1 SV=1
Q9CZW5Mitochondrial import receptor subunit TOM70 OS=Mus musculus OX=10090 GN=Tomm70 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0007045 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00515
all species →
TPR_1Tetratricopeptide repeatRepeatInterproscan
PF13181
all species →
TPR_8Tetratricopeptide repeatRepeatInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR019734
all species →
RepeatTetratricopeptide repeatInterproscan
IPR011990
all species →
Homologous_superfamilyTetratricopeptide-like helical domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46208
all species →
MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan
GO:0008320
all species →
Molecular Functionprotein transmembrane transporter activityInterproscan
GO:0030150
all species →
Biological Processprotein import into mitochondrial matrixInterproscan
GO:0030943
all species →
Molecular Functionmitochondrion targeting sequence bindingInterproscan
GO:0031307
all species →
Cellular Componentobsolete integral component of mitochondrial outer membraneInterproscan
GO:0045039
all species →
Biological Processprotein insertion into mitochondrial inner membraneInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K17768TOM70; mitochondrial import receptor subunit TOM70-Transportersko02000deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000018754 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
35TPM > 0
6Conditions
170.9Max TPM
69.6Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 77.59 116.53
polyp and skeleton · 31C, 3week 6 6 61.45 78.52
polyp and skeleton · 28C, 3week 6 5 73.62 170.86
polyp and skeleton · 26C, 3week 4 4 65.40 72.62
polyp and skeleton · 28C, 24hr 2 2 62.85 69.53
polyp and skeleton · 31C, 24hr 2 1 29.84 59.68

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 116.53
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 110.86
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 87.58
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 85.81
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 84.78
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 79.30
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 78.30
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 77.85
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 76.30
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 73.24
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 72.73
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 71.14
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 69.72
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 66.75
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 60.34
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 55.33
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 52.48
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 78.52
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 68.98
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 67.12
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 63.77
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 51.57
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 38.76
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 170.86
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 77.99
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 65.10
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 64.19
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 63.61
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 72.62
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 70.49
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 66.11
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 52.39
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 69.53
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 56.16
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 59.68
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 0.00

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated33ENSBQFP000000045970.884735026964416
Negatively correlated22ENSBQFP00000001165-0.737674319842337

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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