Detailed information of ENSBQFP00000020576.1 in Heliopora coerulea

Genomic Location: JASJOG010000045.1:921475...941080
NR annotation: XP_028411460.1, uncharacterized protein LOC114534012 [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8VDG5Phosphopantothenate--cysteine ligase OS=Mus musculus OX=10090 GN=Ppcs PE=1 SV=1
Q9HAB8Phosphopantothenate--cysteine ligase OS=Homo sapiens OX=9606 GN=PPCS PE=1 SV=2
Q9USK7Uncharacterized protein C4B3.18 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPCC4B3.18 PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006300 (this species only) · gene tree & orthology
Transcription factor familyHomeobox · all TF in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00046
all species →
HomeodomainHomeodomainDomainInterproscan
PF04127
all species →
DFPDNA / pantothenate metabolism flavoproteinFamilyInterproscan
PF00157
all species →
PouPou domain - N-terminal to homeobox domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR010982
all species →
Homologous_superfamilyLambda repressor-like, DNA-binding domain superfamilyInterproscan
IPR001356
all species →
DomainHomeobox domainInterproscan
IPR000327
all species →
DomainPOU-specific domainInterproscan
IPR050255
all species →
FamilyPOU domain transcription factorInterproscan
IPR013847
all species →
DomainPOU domainInterproscan
IPR009057
all species →
Homologous_superfamilyHomeobox-like domain superfamilyInterproscan
IPR007085
all species →
DomainDNA/pantothenate metabolism flavoprotein, C-terminalInterproscan
IPR035929
all species →
Homologous_superfamilyCoaB-like superfamilyInterproscan
IPR017970
all species →
Conserved_siteHomeobox, conserved siteInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11636
all species →
POU DOMAINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003677
all species →
Molecular FunctionDNA bindingInterproscan
GO:0003700
all species →
Molecular FunctionDNA-binding transcription factor activityInterproscan
GO:0006355
all species →
Biological Processregulation of DNA-templated transcriptionInterproscan
GO:0000978
all species →
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA bindingInterproscan
GO:0000981
all species →
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specificInterproscan
GO:0006357
all species →
Biological Processregulation of transcription by RNA polymerase IIInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for ENSBQFP00000020576.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000020576.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
32TPM > 0
6Conditions
72.0Max TPM
33.6Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 41.23 48.10
polyp and skeleton · 31C, 3week 6 6 37.00 47.42
polyp and skeleton · 28C, 3week 6 4 22.04 36.78
polyp and skeleton · 26C, 3week 4 2 16.28 34.73
polyp and skeleton · 28C, 24hr 2 2 25.21 27.53
polyp and skeleton · 31C, 24hr 2 1 36.01 72.03

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 48.10
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 47.84
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 46.65
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 45.51
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 45.25
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 44.84
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 44.75
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 42.60
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 40.59
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 40.00
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 39.95
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 39.81
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 37.51
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 36.97
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 36.02
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 33.74
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 30.82
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 47.42
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 41.54
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 36.42
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 35.18
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 33.20
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 28.20
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 36.78
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 35.58
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 31.91
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 27.96
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 34.73
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 30.38
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 27.53
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 22.89
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 72.03
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 0.00

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated37ENSBQFP000000060530.897313980020081
Negatively correlated31ENSBQFP00000002318-0.832096466859522

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000020576, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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