Detailed information of ENSBQFP00000021947.1 in Heliopora coerulea

Genomic Location: JASJOG010000058.1:1324877...1331864
NR annotation: CAB3977305.1, importin subunit alpha-7 [Paramuricea clavata]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O15131Importin subunit alpha-6 OS=Homo sapiens OX=9606 GN=KPNA5 PE=1 SV=3
Q9SLX0Importin subunit alpha-1b OS=Oryza sativa subsp. japonica OX=39947 GN=Os05g0155601 PE=1 SV=2
O35345Importin subunit alpha-7 OS=Mus musculus OX=10090 GN=Kpna6 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001131 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00514
all species →		ArmArmadillo/beta-catenin-like repeatRepeatInterproscan
PF01749
all species →		IBBImportin beta binding domainRepeatInterproscan
PF16186
all species →		Arm_3Atypical Arm repeat RepeatInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000225
all species →		RepeatArmadilloInterproscan
IPR011989
all species →		Homologous_superfamilyArmadillo-like helicalInterproscan
IPR002652
all species →		DomainImportin-alpha, importin-beta-binding domainInterproscan
IPR016024
all species →		Homologous_superfamilyArmadillo-type foldInterproscan
IPR036975
all species →		Homologous_superfamilyImportin-alpha, importin-beta-binding domain superfamilyInterproscan
IPR032413
all species →		RepeatAtypical Arm repeatInterproscan
IPR024931
all species →		FamilyImportin subunit alphaInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR23316
all species →		IMPORTIN ALPHAInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005515
all species →		Molecular Functionprotein bindingInterproscan
GO:0006606
all species →		Biological Processprotein import into nucleusInterproscan
GO:0061608
all species →		Molecular Functionnuclear import signal receptor activityInterproscan
GO:0005634
all species →		Cellular ComponentnucleusInterproscan
GO:0005654
all species →		Cellular ComponentnucleoplasmInterproscan
GO:0006607
all species →		Biological ProcessNLS-bearing protein import into nucleusInterproscan
GO:0008139
all species →		Molecular Functionnuclear localization sequence bindingInterproscan
GO:0005737
all species →		Cellular ComponentcytoplasmInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K15042KPNA5_6; importin subunit alpha-6/7-Chromosome and associated proteinsko03036deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000021947.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
32TPM > 0
6Conditions
125.1Max TPM
45.7Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 16 43.23 62.66
polyp and skeleton · 31C, 3week 6 6 55.90 80.52
polyp and skeleton · 28C, 3week 6 4 34.99 71.95
polyp and skeleton · 26C, 3week 4 3 63.10 125.13
polyp and skeleton · 28C, 24hr 2 2 44.97 53.72
polyp and skeleton · 31C, 24hr 2 1 33.68 67.35

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 62.66
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 57.59
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 56.14
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 54.49
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 54.08
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 53.22
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 48.67
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 48.10
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 46.29
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 43.50
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 42.94
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 40.72
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 36.89
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 31.99
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 29.18
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 28.49
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 0.00
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 80.52
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 63.02
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 57.26
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 53.06
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 41.98
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 39.53
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 71.95
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 60.99
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 41.87
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 35.15
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 125.13
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 76.90
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 50.36
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 53.72
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 36.23
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 67.35
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 0.00

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated24ENSBQFP000000333530.880603177587061
Negatively correlated14ENSBQFP00000044849-0.701114955192029

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000021947, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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