Gene detail

Detailed information of ENSBQFP00000024431.1 in Heliopora coerulea

Genomic Location: JASJOG010000063.1:1200702...1209459
NR annotation: CAB3978491.1, dual specificity kinase CLK2 isoform X1 [Paramuricea clavata]
Species Heliopora coerulea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O35491	Dual specificity protein kinase CLK2 OS=Mus musculus OX=10090 GN=Clk2 PE=1 SV=2
P49760	Dual specificity protein kinase CLK2 OS=Homo sapiens OX=9606 GN=CLK2 PE=1 SV=1
P49762	Serine/threonine-protein kinase Doa OS=Drosophila melanogaster OX=7227 GN=Doa PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005528 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR051175 all species →	Family	Dual specificity CLK kinases	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45646 all species →	SERINE/THREONINE-PROTEIN KINASE DOA-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0043484 all species →	Biological Process	regulation of RNA splicing	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08823	CLK2_3; dual specificity protein kinase CLK2/3	EC:2.7.12.1	Spliceosome	ko03041	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000024431.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples

32TPM > 0

6Conditions

257.5Max TPM

43.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole coral	17	16	40.40	67.60
polyp and skeleton · 31C, 3week	6	6	47.64	68.16
polyp and skeleton · 28C, 3week	6	4	23.38	42.46
polyp and skeleton · 26C, 3week	4	2	20.93	42.67
polyp and skeleton · 28C, 24hr	2	2	43.38	47.26
polyp and skeleton · 31C, 24hr	2	2	154.98	257.49

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
ERR6178771	Whole coral	Whole coral	not recorded	not recorded	ERP120267	67.60
ERR6178777	Whole coral	Whole coral	not recorded	not recorded	ERP120267	66.15
ERR6178779	Whole coral	Whole coral	not recorded	not recorded	ERP120267	62.38
ERR6178782	Whole coral	Whole coral	not recorded	not recorded	ERP120267	58.04
ERR6178387	Whole coral	Whole coral	not recorded	not recorded	ERP120267	54.64
ERR6178772	Whole coral	Whole coral	not recorded	not recorded	ERP120267	53.98
ERR6178389	Whole coral	Whole coral	not recorded	not recorded	ERP120267	47.27
ERR6178781	Whole coral	Whole coral	not recorded	not recorded	ERP120267	41.97
ERR6178776	Whole coral	Whole coral	not recorded	not recorded	ERP120267	41.86
ERR6178770	Whole coral	Whole coral	not recorded	not recorded	ERP120267	36.01
ERR6178388	Whole coral	Whole coral	not recorded	not recorded	ERP120267	30.80
ERR6178783	Whole coral	Whole coral	not recorded	not recorded	ERP120267	30.01
ERR6178778	Whole coral	Whole coral	not recorded	not recorded	ERP120267	27.91
ERR6178774	Whole coral	Whole coral	not recorded	not recorded	ERP120267	25.20
ERR6178773	Whole coral	Whole coral	not recorded	not recorded	ERP120267	21.74
ERR6178780	Whole coral	Whole coral	not recorded	not recorded	ERP120267	21.29
ERR6178775	Whole coral	Whole coral	not recorded	not recorded	ERP120267	0.00
SRR12578066	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	68.16
SRR12587804	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	54.06
SRR12587799	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	52.13
SRR12587800	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	49.14
SRR12578068	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	35.74
SRR12578065	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	26.60
SRR12587807	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	42.46
SRR12587802	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	40.95
SRR12587808	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	36.20
SRR12587803	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	20.70
SRR12578067	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	0.00
SRR5949849	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	0.00
SRR12587805	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	42.67
SRR12587798	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	41.04
SRR12587801	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	0.00
SRR12587806	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	0.00
SRR5949850	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	47.26
SRR12578063	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	39.50
SRR5949848	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	257.49
SRR12578064	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	52.48

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.