Gene detail

Detailed information of ENSBQFP00000027105.1 in Heliopora coerulea

Genomic Location: :...
NR annotation: CAB4010257.1, volume-regulated anion channel subunit LRRC8A-like [Paramuricea clavata]

Gene Structure

More details in Jbrowse

Sequence

CDS

ENSBQFT00000030363

ATGCAGAGAACCATCAGACTAGGATGGAAAAGTGACAGAGAGCCAAGAGATAAAGTTGACCACCGCCTTGAAGGAGACACAATGCTGCCCTTGACCGAGTTTGCGAAATTTGAAAGTGCAAAATCTGCCGTCCAGATCGTTAAGCCATGGTGGAACTTGGTCACCGATTATCTCCTGAAGCTCTTGCTAATAATCTCTCTTCTGGTCGGAGGAATGGAATTAACGTCTGGCAGTTTTGATTGCCTACCAACTGTCGACTGCTCTTTGCCGAACAGCCGTACGTTGTTTTCAAAGGCAAACTATCACAACGCATGCACAGTTTTTTTCACCTCTCGAGAAGCAATGGATTGTAAGGGAACAACAGTTGCAGTTGAGCTTAAAAAGTACCCGGCTCACTATGCAAAATATGTCAACTCCGAGTGCAGAAAAACCGCCGTTCATTGGTTTGCTTCCTACTTTTCTTTTATCCTTTTTAGCCAAGCCTTATTTCTTTTTGTACTGGATAACTTCTTGGTTAAATTTCCACCCACAGCGTCAGTTATAGAAACTTTCTCTATTCTAGTCATTGAATGCTACGAGTCACCGGAAACTAGTTTTTGTTTACCACACGAGCTGTTCAACCAACCAGACAGAAACGAAAGAAGTGTAGTTGATAGGAAGCCTGACAAACAAAGATCTGGAGAAAACGAACAACTCCTTAGTAACAAACAGCAGGACAACGAAAGCTTCCCCTCCTCGTCTAAAGCTCGAAGTAGTGAGAGTAAGATTTCTGTTGACATTGCGACAGCTGTTCAAGTTATGGCTTTGTACGAGAAAGTAAAGCGATTTATGGAGCGCATCAAATCGTCTCAAAAGATATGGATAGTGTATCTTATTCAGACTTCAATACAAATCTGTTTAACGGTGGTTTTCGTCTTCTTTAATGCATTCCACGTGACGAGCTTAAAAGGATCAGTGAAGTGCTCAGTGGACAGTGTGTGCATTCCAGTGGTGCACGGTCATTTTACTTGTACCCACAACCTTCAGCCAATGTTCGAAAGGGCTTTGATTGCATTCATTGTAGTTTTAAGTTTATACTTACTTAGTCCTATAGGGGTCGTGATACGGACAATTAGCAAAAACAAGTCCGACAGTGACCACAACATAGCCAATTTCCCTAAATTGGAAAAAGACGCGAGATTCCTGTTGCAATTATTGGAGGCCTATGATAAATCATACGCCCAGCAGTTTCGTAAATACATGTCGGAGAATTCTGAGAAGCATTTGAAggctaaaattttgaaaatgcactGGCCACTGTCAAAACTAGAGGATCATTGTAGTATTAACGAAACTGAGGGAATGACACTTAGTTTGACCGGACTCTCTGGAATTCCGGAGACGTTGTTTGACCTTACCAGTCTTAACAAGTTGGAGCTAAAACGATGTGAACTGCAGCATGACgaatttcatcaaattgagaAATTGCGCAACTTAGAAGACCTCGCCCTAGTTGAATGCAAACTTAATAAAATTCCGGAGAAAATTTTATGCATGACCTGGCTAAAAGTTCTAACTCTCAAGTATAATTCAATCAATACCATTGGATCTGACATAGGAAAGCTCAAAGAGCTGACAACTTTGGATTTAACTGGTAATGAACTGGTAAGCATCGATGAATCCTTGAAAAATCTTGGTAATCTACACACACTTTACCTTTTCAAAAATCCAGAGTTGGGAATAGCGGCAATCAAAACAGCTTTGGAATGcagaatgttgaaaaatttcaaattatctGATTCCAAAATACAAGAGCTCAATGGCGATGTTTTGAGAAAGTACAAAAAACTAAATGAGGTCAGTTGGACAAAAAGATCtaaaaaacatgaagaaaagTTTGCCAACCTCACGAAACTTCCTCGTGAAAAGTTGATCAGGATTGGAACTTTCTATGTACGTTTTGATCAAGAGTTTATGATTGGCAAAGGTCGCGATGGTACACGTGTTTACGTTGGTTTATCAGATGATGGTAATGAAGTAGCCGTGAAACGTATGCTAACCCACACTAGTGAAGACGTGGCCGGAAACGAAGAAAGAATATTGAATATGATGGAAAAGTCGCAGCATATCGTGAGATATCTTTCTTGCACAACTGATGAAACTCACACTTTTACATATCTTGTCCTTGAGTTGTGTGAAGAAACATTGGAGGATTACGTTCATTCACTTAACCAAGAGGAATTAGACCTCTATGCTCCACGTCTGATACGTGAAATACTGACTGGATTGCTGACACTTCATACGGGTAAAGTAACGATTCTCCACAGGGATCTGAATCCATGGAACATTTTGGTCGACGTCGAAGGTCATATGAAGTTGGCAGATTTTGGTGTGAGCAGAAGGCTCAGCCAAGATAGTTCAACTTACAATAGTGCAGGAAATAAAGGAGCCAGATATTGGAGAGCTGTGGAGTCAGTGTCCTTTGAAGAAAAGGATAATGGAAAGTTGTCGTTCACAAAGTTATAA

Transcript

Protein

Uniprot

Uniprot term	Description
Q8TDW0	Volume-regulated anion channel subunit LRRC8C OS=Homo sapiens OX=9606 GN=LRRC8C PE=1 SV=2
Q8IWT6	Volume-regulated anion channel subunit LRRC8A OS=Homo sapiens OX=9606 GN=LRRC8A PE=1 SV=1
Q80WG5	Volume-regulated anion channel subunit LRRC8A OS=Mus musculus OX=10090 GN=Lrrc8a PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12534	Pannexin_like	Pannexin-like TM region of LRRC8	Family	Interproscan
PF13855	LRR_8	Leucine rich repeat	Repeat	Interproscan
PF00069	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR045133	Family	Serine/threonine-protein kinase/endoribonuclease IRE1/2-like	Interproscan
IPR032675	Homologous_superfamily	Leucine-rich repeat domain superfamily	Interproscan
IPR011009	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR021040	Domain	LRRC8, pannexin-like TM region	Interproscan
IPR000719	Domain	Protein kinase domain	Interproscan
IPR001611	Repeat	Leucine-rich repeat	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13954	IRE1-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004521	Molecular Function	RNA endonuclease activity	Interproscan
GO:0004674	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0030968	Biological Process	endoplasmic reticulum unfolded protein response	Interproscan
GO:0036498	Biological Process	IRE1-mediated unfolded protein response	Interproscan
GO:0051082	Molecular Function	unfolded protein binding	Interproscan
GO:0070059	Biological Process	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Interproscan
GO:1990604	Cellular Component	IRE1-TRAF2-ASK1 complex	Interproscan
GO:0004672	Molecular Function	protein kinase activity	Interproscan
GO:0005524	Molecular Function	ATP binding	Interproscan
GO:0006468	Biological Process	protein phosphorylation	Interproscan
GO:0005515	Molecular Function	protein binding	Interproscan