Gene detail

Detailed information of ENSBQFP00000027328.1 in Heliopora coerulea

Genomic Location: :...
NR annotation: CAB3986231.1, proto-oncogene vav-like [Paramuricea clavata]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
P52735	Guanine nucleotide exchange factor VAV2 OS=Homo sapiens OX=9606 GN=VAV2 PE=1 SV=2
Q9R0C8	Guanine nucleotide exchange factor VAV3 OS=Mus musculus OX=10090 GN=Vav3 PE=1 SV=2
Q60992	Guanine nucleotide exchange factor VAV2 OS=Mus musculus OX=10090 GN=Vav2 PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00130	C1_1	Phorbol esters/diacylglycerol binding domain (C1 domain)	Domain	Interproscan
PF00621	RhoGEF	RhoGEF domain	Domain	Interproscan
PF00307	CH	Calponin homology (CH) domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001715	Domain	Calponin homology domain	Interproscan
IPR000219	Domain	Dbl homology (DH) domain	Interproscan
IPR011993	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR036872	Homologous_superfamily	CH domain superfamily	Interproscan
IPR001331	Conserved_site	Guanine-nucleotide dissociation stimulator, CDC24, conserved site	Interproscan
IPR002219	Domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Interproscan
IPR035899	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR046349	Homologous_superfamily	C1-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45818	PROTEIN VAV	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005515	Molecular Function	protein binding	Interproscan
GO:0005085	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0035556	Biological Process	intracellular signal transduction	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan
GO:0016477	Biological Process	cell migration	Interproscan
GO:0043087	Biological Process	regulation of GTPase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K05730	VAV; guanine nucleotide exchange factor VAV	-	Lipid and atherosclerosis	ko05417	deepkoala