Detailed information of ENSBQFP00000028226.1 in Heliopora coerulea

Genomic Location: JASJOG010000089.1:116684...119892
NR annotation: XP_027044065.1, DNA-directed RNA polymerase III subunit RPC10-like [Pocillopora damicornis]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9Y2Y1DNA-directed RNA polymerase III subunit RPC10 OS=Homo sapiens OX=9606 GN=POLR3K PE=1 SV=3
Q9CQZ7DNA-directed RNA polymerase III subunit RPC10 OS=Mus musculus OX=10090 GN=Polr3k PE=3 SV=1
Q2M2S7DNA-directed RNA polymerase III subunit RPC10 OS=Bos taurus OX=9913 GN=POLR3K PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0009244 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01096
all species →
TFIIS_CTranscription factor S-II (TFIIS)DomainInterproscan
PF02150
all species →
RNA_POL_M_15KDRNA polymerases M/15 Kd subunitDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR001222
all species →
DomainZinc finger, TFIIS-typeInterproscan
IPR001529
all species →
DomainDNA-directed RNA polymerase, M/15kDa subunitInterproscan
IPR012164
all species →
FamilyDNA-directed RNA polymerase subunit/transcription factor SInterproscan
IPR034014
all species →
DomainPol III subunit C11, C-terminal zinc ribbonInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11239
all species →
DNA-DIRECTED RNA POLYMERASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003676
all species →
Molecular Functionnucleic acid bindingInterproscan
GO:0006351
all species →
Biological ProcessDNA-templated transcriptionInterproscan
GO:0008270
all species →
Molecular Functionzinc ion bindingInterproscan
GO:0001056
all species →
Molecular FunctionRNA polymerase III activityInterproscan
GO:0003899
all species →
Molecular FunctionDNA-directed 5'-3' RNA polymerase activityInterproscan
GO:0005666
all species →
Cellular ComponentRNA polymerase III complexInterproscan
GO:0006386
all species →
Biological Processtermination of RNA polymerase III transcriptionInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K03019RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC11-Transcription machineryko03021deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000028226.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
27TPM > 0
6Conditions
74.7Max TPM
26.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 12 25.83 74.72
polyp and skeleton · 31C, 3week 6 6 43.85 59.53
polyp and skeleton · 28C, 3week 6 4 13.79 30.07
polyp and skeleton · 26C, 3week 4 2 16.57 34.32
polyp and skeleton · 28C, 24hr 2 2 40.93 45.91
polyp and skeleton · 31C, 24hr 2 1 22.46 44.91

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 74.72
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 47.17
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 42.05
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 35.80
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 35.05
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 34.02
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 32.39
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 29.30
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 29.03
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 29.01
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 28.47
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 22.13
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 0.00
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 0.00
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 0.00
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 0.00
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 0.00
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 59.53
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 55.20
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 44.66
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 44.57
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 39.57
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 19.56
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 30.07
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 22.10
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 21.65
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 8.92
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 34.32
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 31.97
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 45.91
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 35.95
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 44.91
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 0.00

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated21ENSBQFP000000331880.882447610479562
Negatively correlated4ENSBQFP00000049838-0.718715206313938

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000028226, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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