Detailed information of ENSBQFP00000031141.1 in Heliopora coerulea

Genomic Location: JASJOG010000086.1:1334040...1353121
NR annotation: XP_028399494.1, adhesion G-protein coupled receptor G6-like [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
C6KFA3Adhesion G-protein coupled receptor G6 OS=Danio rerio OX=7955 GN=adgrg6 PE=1 SV=1
B7ZCC9Adhesion G-protein coupled receptor G4 OS=Mus musculus OX=10090 GN=Adgrg4 PE=3 SV=1
Q8IZF6Adhesion G-protein coupled receptor G4 OS=Homo sapiens OX=9606 GN=ADGRG4 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000552 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00059
all species →
Lectin_CLectin C-type domainDomainInterproscan
PF01825
all species →
GPSGPCR proteolysis site, GPS, motif MotifInterproscan
PF00002
all species →
7tm_27 transmembrane receptor (Secretin family)FamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR001304
all species →
DomainC-type lectin-likeInterproscan
IPR000832
all species →
FamilyGPCR, family 2, secretin-likeInterproscan
IPR000203
all species →
Conserved_siteGPS motifInterproscan
IPR017983
all species →
Conserved_siteGPCR, family 2, secretin-like, conserved siteInterproscan
IPR016186
all species →
Homologous_superfamilyC-type lectin-like/link domain superfamilyInterproscan
IPR016187
all species →
Homologous_superfamilyC-type lectin foldInterproscan
IPR018378
all species →
Conserved_siteC-type lectin, conserved siteInterproscan
IPR046338
all species →
Homologous_superfamilyGAIN domain superfamilyInterproscan
IPR001879
all species →
DomainGPCR, family 2, extracellular hormone receptor domainInterproscan
IPR053066
all species →
FamilyAdhesion G-protein coupled receptor G7Interproscan
IPR036445
all species →
Homologous_superfamilyGPCR family 2, extracellular hormone receptor domain superfamilyInterproscan
IPR017981
all species →
DomainGPCR, family 2-like, 7TMInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR47767
all species →
ADHESION G PROTEIN-COUPLED RECEPTOR G7Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004930
all species →
Molecular FunctionG protein-coupled receptor activityInterproscan
GO:0007186
all species →
Biological ProcessG protein-coupled receptor signaling pathwayInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0004888
all species →
Molecular Functiontransmembrane signaling receptor activityInterproscan
GO:0007166
all species →
Biological Processcell surface receptor signaling pathwayInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for ENSBQFP00000031141.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000031141.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
34TPM > 0
6Conditions
18.1Max TPM
8.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 10.79 17.06
polyp and skeleton · 31C, 3week 6 6 7.66 10.54
polyp and skeleton · 28C, 3week 6 5 5.66 18.13
polyp and skeleton · 26C, 3week 4 3 7.08 12.15
polyp and skeleton · 28C, 24hr 2 2 4.40 5.04
polyp and skeleton · 31C, 24hr 2 1 7.25 14.51

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 17.06
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 15.31
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 13.87
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 13.76
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 13.31
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 11.97
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 11.83
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 11.50
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 10.89
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 10.50
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 10.33
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 9.84
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 9.77
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 8.04
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 6.93
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 5.56
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 3.02
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 10.54
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 10.09
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 8.18
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 6.88
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 5.70
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 4.55
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 18.13
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 5.14
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 4.74
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 3.08
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 2.87
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 12.15
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 9.16
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 7.01
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 5.04
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 3.75
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 14.51
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 0.00

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated14ENSBQFP000000508290.80547908952048
Negatively correlated7ENSBQFP00000045021-0.774913626236102

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000031141, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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