Gene detail

Detailed information of ENSBQFP00000031753.1 in Heliopora coerulea

Genomic Location: JASJOG010000085.1:574354...590600
NR annotation: XP_028398258.1, coatomer subunit gamma-2-like [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSBQFT00000035580

atgcattacttaagACAAGATAAGAAAGATGAGGAAGAGGGTAGGGGATCAAATCCTTTTCAAGGTTTGGATAAGGCCACTGCACTTCAAGAGGCAAGAACTTTTAATGAAAGTCCAATAAATCCACGAAAATGTATCCACATTCTCACAAAGATTCTGTACCTTTTAAATCAAgGTCAGCAATTTGGAACAACTGAAGCAACAGAAGCATTTTTTGCAATGACAAAACTTTTTCAGTCAAAAGATCCAATGTTACGTCGTATGGTTTACCTTGCCATCAAAGAACTGTCTAGTGTAGCTGAAGATGTTATTATTGTGACAAGTAGTTTGACCAAGGATATGACAGGCAGGGAAGAGGCATATTGTGCCAATGCAATCCGTGCCTTGTGTATGATCACAGATGCCACCATGCTTCAAGCCATTGAGAGATACATGAAGCAAGCTATTGTGGATAAAAGTCACAGTGTCTCTAGCAATGCACTGGTTTCATCTTTGCATTTACTGAAAGACAGCTTTGATGTTGTGAAGCGATGGGTTAATGAAGCTCAGGAAATGGTTTCAAGTGATTCAGTGATGGTACAGTATCATGGTCTTGGCTTATTGTACCACATTAAGAAGCAAGATCGCTTAGCCATTTCAAAACTTTTGACCAAATTTACAAAGCAATCCTTGAAGTCTCCATATGCCATGTGTATGATGATACGTATTGCAGCAAAATTCTTGGCTGAAGAGGATGAAGGCACTTCGAGCCCCTTGTATGATTTCCTTGAAAACTGCCTTCGAAATAAGAGTGAGATAGTGATCTACGAAGCAGCCCGCGCCCTTGTAAACTTGAAAAATGTCGAGTCGCGAGATCTTTGCCCAGCCATTTCTGTTTTACAGCTATTCCTTAGTTCTCCCAGACCAACACTGAGGTTTGCTGCTGTTCGTACGTTGAACAAAGTGGCCATGACACAACCGGCGTCAGTGACCAGCTGTAACCTTGACCTGGAGAACTTGATTACTGATGTGAATCGCAGTATTGCCACTTTGGCCATAACCACGCTACTTAAGACCGGCAGTGAAGCAAGCATCGATCGTCTGATGAAGCAAATTTCCTCGTTTATGTCGGAGATCTCCGATGAGTTTAAGATTGTCGTGGTGGATGCTATCAAGTCCTTGTGCTTGAAGTTTCCTCGTAAGCACATGGTGATGATGAACTTCCTTTCCTCAATGTTGCGTGACGACGGTGGATTTGAGTACAAGAAAGCTATTGTGAACACTATAATCGACATTGTTGAGGAAAATTCAGATGCCAAAGAATCGGGTCTTTCACATTTGTGCGAATTCATCGAAGATTGTGAGCATACTGTTCTAGCCACACGAATCCTGCACTTGCTTGGCAGAGAAGGACCGCGAACTCAGAAGCCTGCCAAGTATATTCGATTTATTTACAATCGTGTTATCCTGGAAAACGCTGCGGTGAGAGCAGCCGCTGTTACTACTCTAGCTAAATTTGGTGCTCATTGTGAACTACTTTTGCCCAGCATTCAAGTCTTGTTGTCACGCTGCTTATTAGACACTGATGACGAAGTTCGGGACAGGGCCACCTTTTATCTGAACGTGCTGAAGGAAAAGGACAAGGCGTTGTCATCGGCGTACATACTTAACGGTCTTCAAGTTTCTGTGGTTGGTTTAGAGCGCGCCTTGAATGCCTATGTGAAAGAATGCCCAGATACTCCGTTTGACATCAAAACCGTACCCTTGGCAACGTCTTCCATGCAAGAACAAATGACAAAGCCTGCCAAACCAACCAAAACGGAAGTACCCTCAGTCCAGCCTACCGTAGCCACTTCAACGCAAGAGATTTATGGAGAACAACTTGCTGCGATCCCAGAGTTTGCAAGCCTTGGTCCATTGTTCAAGTCTTCCTCTAAGCCAGTGGAGCTGACAGAATCGGAGACTGAATATGTGGTTCATTGCGTCAAACATGTTTTCCGTAATCACATTGTGTTTCAGTATGATTGTACGAACACCCTTAATGACCAAATCTTGGAGAATGTCACTGTTGAAATGGAGGTGTCGGATGGCGAGTATGACGTCCTTAAGACTATTCCTTGCCCTAGTTTACCATATAACACACCTGGTACCACCTATGTTCTTGTTAAAATACCAGATGATCAGACCGAAGTTACGGCAACCTTTTCTAATACGATGAAATTCGTCGTGAAGGATTGCGACCCGAACACTGGTGAGGCAGACGACGAAGGATATGACGACGAATATGTGTTGGAGGACATTGAAGTTGTCGTCGCTGACCACGTGCAAAAAGTTCTTAAGACCAACTTTGGCGCCTCGTGGGAGGAGATTGGAGACAGTCACGAGATGAAGGACACGTACGCATTGTCGCAGATGAAAAGCTTGGACGACGCCGTCAAGCAAATTATTGAATACATGGGAATGCAACCTTGCGAGCGCTCTGATAGAGTATCCCCGGATAAAAGTTCCCATGTGTTGTTATTGGCTGGTTGTTACCGCGGCGGGCACGATGTCCTCGTTCAAACAAGACTGGCGTTCAGCGATGGCGTAACGATGCAAATTACAGTTCGTAGTACCGACGCGACGGTCAGCGAAGTGGTTCTGTCGGCAGTTGGTTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9I8E6	Coatomer subunit gamma-2 OS=Takifugu rubripes OX=31033 GN=copg2 PE=3 SV=1
Q9PUE4	Coatomer subunit gamma-2 OS=Danio rerio OX=7955 GN=copg2 PE=2 SV=2
Q66JI9	Coatomer subunit gamma-2 OS=Xenopus tropicalis OX=8364 GN=copg2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005625 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16381 all species →	Coatomer_g_Cpla	Coatomer subunit gamma-1 C-terminal appendage platform	Domain	Interproscan
PF01602 all species →	Adaptin_N	Adaptin N terminal region	Repeat	Interproscan
PF08752 all species →	COP-gamma_platf	Coatomer gamma subunit appendage platform subdomain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037067 all species →	Homologous_superfamily	Coatomer, gamma subunit, appendage domain superfamily	Interproscan
IPR012295 all species →	Homologous_superfamily	TBP domain superfamily	Interproscan
IPR017106 all species →	Family	Coatomer gamma subunit	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR032154 all species →	Domain	Coatomer subunit gamma, C-terminal	Interproscan
IPR002553 all species →	Domain	Clathrin/coatomer adaptor, adaptin-like, N-terminal	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR013040 all species →	Domain	Coatomer, gamma subunit, appendage, Ig-like subdomain	Interproscan
IPR013041 all species →	Homologous_superfamily	Clathrin adaptor, appendage, Ig-like subdomain superfamily	Interproscan
IPR009028 all species →	Homologous_superfamily	Coatomer/calthrin adaptor appendage, C-terminal subdomain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10261 all species →	COATOMER SUBUNIT GAMMA	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005198 all species →	Molecular Function	structural molecule activity	Interproscan
GO:0006886 all species →	Biological Process	intracellular protein transport	Interproscan
GO:0016192 all species →	Biological Process	vesicle-mediated transport	Interproscan
GO:0030126 all species →	Cellular Component	COPI vesicle coat	Interproscan
GO:0030117 all species →	Cellular Component	membrane coat	Interproscan
GO:0000139 all species →	Cellular Component	Golgi membrane	Interproscan
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:0005793 all species →	Cellular Component	endoplasmic reticulum-Golgi intermediate compartment	Interproscan
GO:0006888 all species →	Biological Process	endoplasmic reticulum to Golgi vesicle-mediated transport	Interproscan
GO:0006891 all species →	Biological Process	intra-Golgi vesicle-mediated transport	Interproscan
GO:0009306 all species →	Biological Process	protein secretion	Interproscan
GO:0072384 all species →	Biological Process	organelle transport along microtubule	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K17267	COPG; coatomer subunit gamma	-	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000031753.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples

36TPM > 0

6Conditions

646.9Max TPM

203.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole coral	17	17	166.27	222.83
polyp and skeleton · 31C, 3week	6	6	241.64	336.92
polyp and skeleton · 28C, 3week	6	5	232.25	646.94
polyp and skeleton · 26C, 3week	4	4	196.43	341.20
polyp and skeleton · 28C, 24hr	2	2	205.57	243.05
polyp and skeleton · 31C, 24hr	2	2	334.07	401.69

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
ERR6178775	Whole coral	Whole coral	not recorded	not recorded	ERP120267	222.83
ERR6178773	Whole coral	Whole coral	not recorded	not recorded	ERP120267	220.86
ERR6178778	Whole coral	Whole coral	not recorded	not recorded	ERP120267	203.39
ERR6178774	Whole coral	Whole coral	not recorded	not recorded	ERP120267	194.69
ERR6178388	Whole coral	Whole coral	not recorded	not recorded	ERP120267	187.43
ERR6178389	Whole coral	Whole coral	not recorded	not recorded	ERP120267	182.66
ERR6178387	Whole coral	Whole coral	not recorded	not recorded	ERP120267	175.51
ERR6178776	Whole coral	Whole coral	not recorded	not recorded	ERP120267	174.92
ERR6178771	Whole coral	Whole coral	not recorded	not recorded	ERP120267	174.65
ERR6178781	Whole coral	Whole coral	not recorded	not recorded	ERP120267	159.34
ERR6178780	Whole coral	Whole coral	not recorded	not recorded	ERP120267	155.10
ERR6178770	Whole coral	Whole coral	not recorded	not recorded	ERP120267	149.71
ERR6178772	Whole coral	Whole coral	not recorded	not recorded	ERP120267	146.78
ERR6178783	Whole coral	Whole coral	not recorded	not recorded	ERP120267	140.92
ERR6178779	Whole coral	Whole coral	not recorded	not recorded	ERP120267	131.05
ERR6178777	Whole coral	Whole coral	not recorded	not recorded	ERP120267	113.49
ERR6178782	Whole coral	Whole coral	not recorded	not recorded	ERP120267	93.22
SRR12578065	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	336.92
SRR12587804	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	300.70
SRR12578068	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	282.38
SRR12587799	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	221.46
SRR12578066	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	216.02
SRR12587800	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	92.35
SRR5949849	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	646.94
SRR12587803	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	232.67
SRR12587802	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	225.13
SRR12587808	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	153.25
SRR12587807	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	135.53
SRR12578067	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	0.00
SRR12587801	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	341.20
SRR12587806	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	217.01
SRR12587798	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	115.34
SRR12587805	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	112.18
SRR5949850	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	243.05
SRR12578063	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	168.09
SRR12578064	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	401.69
SRR5949848	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	266.45

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	15	ENSBQFP00000001270	0.916144055922044
Negatively correlated	20	ENSBQFP00000029210	-0.710888107571853

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000031753, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →