Gene detail

Detailed information of ENSBQFP00000033524.1 in Heliopora coerulea

Genomic Location: JASJOG010000138.1:393868...412074
NR annotation: XP_028411083.1, dynamin-1-like isoform X1 [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSBQFT00000037550

ATGGCAGGGAACAGGGGAATGGAAGATCTTATTCCCATTGTCAACAAACTCCAGGACGCTTTCTCGCAGTTAGGGCAATCAGCATCGATAGATTTGCCCCAAATTGCAGTGGTTGGAAGTCAAAGTGCTGGGAAGAGTAGTGTATTGGAGAATTTTGTTGGCAGAGATTTCCTCCCTCGTGGTTCTGGTATTGTAACCAGGCGACCATTGATTTTGCAGCTAATTCCAGATAAAGCTGAGTATGGTGAGTTCCTGCACTCTAAAGGAAAGATGTTCTCTGACTTCAATGAGATCAATAAGGAAATTGTGAAAGAGACAGATCGTATAACTGGAGGAAATAAAGGAATCTCGAATATTCCAATTAATCTGAGGATTCATTCACCTCATGTTTTAAATCTTACATTAATTGATCTCCCTGGCATGACCAAAGTTCCTGTTGGTGACCAACCTGCCGACATTGAACAGCAAATTCGTGACATGTTATACCAGTTTATTACAAAAGATAACTGTCTAATTTTGGCTGTCACCCCTGCAAACACTGATCTGGCAAACTCAGATGCCTTGAAGATTTCACGAGAGGTTGATCCACAAGGTATTCGCACAATTGGTGTAATTACCAAACTTGATTTAATGGACCCAGGAACAGATGCTAGAGAGGTTCTTGAAAATAGAACATTTCCCTTGAGAAGGGGTTATGTCGGAGTAGTTAATCGAAGCCAAAAAGACATTGATGGCAGGAAGGATATCAGAGCTGCAATGGCGTCAGAGAGAAAGTTCTTCTTAGGCCATGCGAGCTATAGGCATATGGCTGATCGAATGGGGACGCCTTATTTACAGAAAGTTCTCAACCAGCAACTGACGAATCACATTCGCGACAGTTTGCCATCGTTAAGAAGCAACCTTCAGGACCAGTTAATGTCCCTGGAGAAGGATGTTGCGGAGTTTAAAAACTTCAGACCTGACGATCCCTCCATGAAAACCAAGGCATTGATGCAaatgaTCCAGCAATTTCAtagtgattttgaaaaagccATCGAGGGGACAGGTGATCAAGTCGATACGTTGCAGCTGTCGGGAGGTGCGCGAATAAACCGTGTGTTTCACGAGCGATTTCCTTACGAACTTGTCAAGATGGAGTTTGACGAACGGGAACTTCGAAAAGAAATTAGCTTTGCTATAAAAAATATCCATGGAGTAAGAGTTGGTCTGTTCACGCCAGACATGGCATTCGAAGCAATTGTCAAGAAACAGATTGACAAGCTCAAGACACCAGCTACAAAATGTATTGATTTAGTTATGAATGAGGTCAACAACGTTATCCGGAAATGCACTAATAAGATGGCCAAGTACCCTCGTCTGCGTGATGAAGTGGAAAGAATTGTTTCAGAGCACATCAAAATAGGAGAAGTCAAAGCCAAAGAACATGTGACTCTTCTGATAGATATTGAACTTTCTTATATCAATACGAACCACCAAGATTTCATTGGCTATGCTGCAGCAAGCTCCAATGCCAATGCAGTGAGCGGTGAGCGGAAAAGAAAAGGTATTGGAAATCAGGTTATCAGAAAAGGATGGCTACAGATTACCAATACTGGTTTTATGAAAAGTGTCGTGGCTAAAGAATATTGGTTTATTTTAACAGCTGAGTCTCTGTCATGGTACAAGGATGAAGAAGAAAAAGAACAGAAATACCAGCTTCGTTTGGAGGGATGTAAATTGCGAGATATGGAAGCTGGCTGGCTGGCGAGGAAAGCAGCATTTGCAATCTTTAATCCTGATCAGAAGAACTTGTTCAAAGACCACAAGCAGCTTGAACTGGCTGCTGAGACGCAAGATGTAGTGGACGAATGGAAAGCATCGTTTCTGAGAGCAGGTGTTTATCCGCAAAGAGAGAAGAATGACTCAGATAGCTCGATCAGTGAGATAGGAAGTCTTGATCCTCAGATGGAAAGGCAGGTGGAAACCATTCGAAATCTCGTGGACTCCTACATTAAAATTGTCAGCAAAACTGTCAGAGATCTTGTACCCAAAACGTGCATGTTCATGATCGTACAAAATACTAAAGAATTCATTGCCTCGGAGATTTTGGCCCACCTCTATTCCAGAGGTGACACGAAATCATTGATGGAAGAGAGTGAGGAAGAGACGCTGCGCCGAGAGGAGATGCTTCGTCTATACCACTGTACCAAACAAGCTCTGGATATTATAGGTGACATAAATATGCACACCGTATCGACACCTTTACCTCCACCAATAGAGAAAGATGACAGTGAGCCACCATCATCCTATAGAGGACCACCTGCAAGtcGTCCACTACCTGTCCCAGCGTCATCCCGAAATGCTCCAGGCAGTCCCACTCCCTCCAGAAACCCTCCTCCACGAACTCGGCCCAATACACGGCCATCGTATCCGGATCGCAGTGAGATAAACTCAACCATGCAAAATGCTCAGAATGCATATACCGCGTACAACATGGCCTCTTCCGTTGGATTAACACCACCAATCCCTAACCGTCCTGATTCGTCCTCGATACCGTCAATACCAAAgcGGCCTGTTATGTCTCGTCCTGCTCCCCCGCCACCAGGTAAGACCCCTAGTATCCCCAGTCGTCCTGACATCCCAAGCAGACCGTATTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P39053	Dynamin-1 OS=Mus musculus OX=10090 GN=Dnm1 PE=1 SV=2
P21575	Dynamin-1 OS=Rattus norvegicus OX=10116 GN=Dnm1 PE=1 SV=2
Q08DF4	Dynamin-1 OS=Bos taurus OX=9913 GN=DNM1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001302 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00350 all species →	Dynamin_N	Dynamin family	Domain	Interproscan
PF01031 all species →	Dynamin_M	Dynamin central region	Family	Interproscan
PF00169 all species →	PH	PH domain	Domain	Interproscan
PF02212 all species →	GED	Dynamin GTPase effector domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR045063 all species →	Domain	Dynamin, N-terminal	Interproscan
IPR022812 all species →	Family	Dynamin	Interproscan
IPR001401 all species →	Domain	Dynamin, GTPase domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR000375 all species →	Domain	Dynamin stalk domain	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR003130 all species →	Domain	Dynamin GTPase effector	Interproscan
IPR019762 all species →	Conserved_site	Dynamin, GTPase region, conserved site	Interproscan
IPR030381 all species →	Domain	Dynamin-type guanine nucleotide-binding (G) domain	Interproscan
IPR020850 all species →	Domain	GTPase effector domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11566 all species →	DYNAMIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003924 all species →	Molecular Function	GTPase activity	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005874 all species →	Cellular Component	microtubule	Interproscan
GO:0008017 all species →	Molecular Function	microtubule binding	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01528	DNM1_3; dynamin 1/3	EC:3.6.5.5	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000033524.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples

35TPM > 0

6Conditions

102.8Max TPM

55.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole coral	17	17	47.73	65.62
polyp and skeleton · 31C, 3week	6	6	65.33	100.29
polyp and skeleton · 28C, 3week	6	5	59.26	92.15
polyp and skeleton · 26C, 3week	4	3	51.16	102.82
polyp and skeleton · 28C, 24hr	2	2	64.00	69.83
polyp and skeleton · 31C, 24hr	2	2	71.29	87.43

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
ERR6178775	Whole coral	Whole coral	not recorded	not recorded	ERP120267	65.62
ERR6178773	Whole coral	Whole coral	not recorded	not recorded	ERP120267	65.13
ERR6178774	Whole coral	Whole coral	not recorded	not recorded	ERP120267	65.02
ERR6178778	Whole coral	Whole coral	not recorded	not recorded	ERP120267	59.80
ERR6178387	Whole coral	Whole coral	not recorded	not recorded	ERP120267	53.05
ERR6178771	Whole coral	Whole coral	not recorded	not recorded	ERP120267	52.70
ERR6178776	Whole coral	Whole coral	not recorded	not recorded	ERP120267	49.40
ERR6178781	Whole coral	Whole coral	not recorded	not recorded	ERP120267	48.47
ERR6178389	Whole coral	Whole coral	not recorded	not recorded	ERP120267	45.79
ERR6178770	Whole coral	Whole coral	not recorded	not recorded	ERP120267	44.82
ERR6178388	Whole coral	Whole coral	not recorded	not recorded	ERP120267	44.19
ERR6178780	Whole coral	Whole coral	not recorded	not recorded	ERP120267	43.44
ERR6178782	Whole coral	Whole coral	not recorded	not recorded	ERP120267	41.71
ERR6178779	Whole coral	Whole coral	not recorded	not recorded	ERP120267	36.97
ERR6178772	Whole coral	Whole coral	not recorded	not recorded	ERP120267	33.98
ERR6178783	Whole coral	Whole coral	not recorded	not recorded	ERP120267	32.15
ERR6178777	Whole coral	Whole coral	not recorded	not recorded	ERP120267	29.16
SRR12578065	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	100.29
SRR12578066	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	80.44
SRR12587804	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	66.02
SRR12578068	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	56.41
SRR12587800	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	46.24
SRR12587799	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	42.61
SRR5949849	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	92.15
SRR12587802	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	80.48
SRR12587807	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	67.72
SRR12587803	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	61.93
SRR12587808	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	53.30
SRR12578067	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	0.00
SRR12587806	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	102.82
SRR12587805	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	51.84
SRR12587798	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	49.98
SRR12587801	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	0.00
SRR5949850	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	69.83
SRR12578063	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	58.17
SRR12578064	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	87.43
SRR5949848	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	55.15

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	23	ENSBQFP00000040915	0.826194830774668
Negatively correlated	42	ENSBQFP00000049804	-0.775946777281171

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000033524, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →