Genomic Location: JASJOG010000139.1:384247...396091
NR annotation: CAB4000122.1, vesicle transport through interaction with t-SNAREs homolog 1B-like [Paramuricea clavata]
Species Heliopora coerulea · all data for this species · gene families
| CDS |
| ENSBQFT00000039250 |
| Protein |
| ENSBQFP00000035023.1 |
| UniProt accession | Description |
|---|---|
| P58200 | Vesicle transport through interaction with t-SNAREs homolog 1B OS=Rattus norvegicus OX=10116 GN=Vti1b PE=1 SV=2 |
| Q9UEU0 | Vesicle transport through interaction with t-SNAREs homolog 1B OS=Homo sapiens OX=9606 GN=VTI1B PE=1 SV=3 |
| O88384 | Vesicle transport through interaction with t-SNAREs homolog 1B OS=Mus musculus OX=10090 GN=Vti1b PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002023 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05008 all species → | V-SNARE | Vesicle transport v-SNARE protein N-terminus | Family | Interproscan |
| PF12352 all species → | V-SNARE_C | Snare region anchored in the vesicle membrane C-terminus | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR007705 all species → | Domain | Vesicle transport v-SNARE, N-terminal | Interproscan |
| IPR038407 all species → | Homologous_superfamily | Vesicle transport v-SNARE, N-terminal domain superfamily | Interproscan |
| IPR000727 all species → | Domain | Target SNARE coiled-coil homology domain | Interproscan |
| IPR010989 all species → | Homologous_superfamily | SNARE | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21230 all species → | VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006886 all species → | Biological Process | intracellular protein transport | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0000149 all species → | Molecular Function | SNARE binding | Interproscan |
| GO:0005484 all species → | Molecular Function | SNAP receptor activity | Interproscan |
| GO:0005789 all species → | Cellular Component | endoplasmic reticulum membrane | Interproscan |
| GO:0005794 all species → | Cellular Component | Golgi apparatus | Interproscan |
| GO:0006891 all species → | Biological Process | intra-Golgi vesicle-mediated transport | Interproscan |
| GO:0006896 all species → | Biological Process | Golgi to vacuole transport | Interproscan |
| GO:0006906 all species → | Biological Process | vesicle fusion | Interproscan |
| GO:0012507 all species → | Cellular Component | ER to Golgi transport vesicle membrane | Interproscan |
| GO:0016236 all species → | Biological Process | macroautophagy | Interproscan |
| GO:0031201 all species → | Cellular Component | SNARE complex | Interproscan |
| GO:0031902 all species → | Cellular Component | late endosome membrane | Interproscan |
| GO:0042147 all species → | Biological Process | retrograde transport, endosome to Golgi | Interproscan |
| GO:0048280 all species → | Biological Process | vesicle fusion with Golgi apparatus | Interproscan |
| GO:1903076 all species → | Biological Process | regulation of protein localization to plasma membrane | Interproscan |
| GO:0016192 all species → | Biological Process | vesicle-mediated transport | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K08493 | VTI1; vesicle transport through interaction with t-SNAREs 1 | - | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of ENSBQFP00000035023.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Whole coral | 17 | 17 | 76.60 | 104.54 | |
| polyp and skeleton · 31C, 3week | 6 | 6 | 72.89 | 111.62 | |
| polyp and skeleton · 28C, 3week | 6 | 5 | 79.23 | 191.28 | |
| polyp and skeleton · 26C, 3week | 4 | 3 | 63.80 | 133.87 | |
| polyp and skeleton · 28C, 24hr | 2 | 2 | 55.86 | 62.92 | |
| polyp and skeleton · 31C, 24hr | 2 | 1 | 38.90 | 77.80 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| ERR6178771 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 104.54 |
| ERR6178780 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 95.58 |
| ERR6178779 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 92.07 |
| ERR6178777 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 91.86 |
| ERR6178772 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 88.03 |
| ERR6178387 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 87.22 |
| ERR6178782 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 87.07 |
| ERR6178388 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 82.29 |
| ERR6178781 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 80.35 |
| ERR6178783 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 73.50 |
| ERR6178770 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 71.51 |
| ERR6178389 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 69.07 |
| ERR6178776 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 69.06 |
| ERR6178775 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 65.74 |
| ERR6178773 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 50.25 |
| ERR6178774 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 47.79 |
| ERR6178778 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 46.21 |
| SRR12587799 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 111.62 |
| SRR12587804 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 75.15 |
| SRR12578065 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 70.63 |
| SRR12587800 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 67.86 |
| SRR12578066 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 67.07 |
| SRR12578068 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 45.00 |
| SRR5949849 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 191.28 |
| SRR12587807 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 110.35 |
| SRR12587802 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 86.89 |
| SRR12587808 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 48.89 |
| SRR12587803 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 37.99 |
| SRR12578067 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 0.00 |
| SRR12587801 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 133.87 |
| SRR12587805 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 68.50 |
| SRR12587798 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 52.85 |
| SRR12587806 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 0.00 |
| SRR12578063 | polyp and skeleton · 28C, 24hr | polyp and skeleton | not recorded | 28C, 24hr | SRP115860 | 62.92 |
| SRR5949850 | polyp and skeleton · 28C, 24hr | polyp and skeleton | not recorded | 28C, 24hr | SRP115860 | 48.80 |
| SRR12578064 | polyp and skeleton · 31C, 24hr | polyp and skeleton | not recorded | 31C, 24hr | SRP115860 | 77.80 |
| SRR5949848 | polyp and skeleton · 31C, 24hr | polyp and skeleton | not recorded | 31C, 24hr | SRP115860 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (HCOER_TPM,
StringTie quantification over 37 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 19 | ENSBQFP00000020642 | 0.843366738706511 |
| Negatively correlated | 21 | ENSBQFP00000000031 | -0.758467014880166 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000035023, the spelling this network uses.
Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
