Genomic Location: JASJOG010000212.1:162230...165892
NR annotation: XP_028393677.1, LOW QUALITY PROTEIN: GDH/6PGL endoplasmic bifunctional protein-like [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families
| CDS |
| ENSBQFT00000046372 |
| Protein |
| ENSBQFP00000041262.1 |
| UniProt accession | Description |
|---|---|
| O95479 | GDH/6PGL endoplasmic bifunctional protein OS=Homo sapiens OX=9606 GN=H6PD PE=1 SV=2 |
| Q8CFX1 | GDH/6PGL endoplasmic bifunctional protein OS=Mus musculus OX=10090 GN=H6pd PE=1 SV=2 |
| P56201 | GDH/6PGL endoplasmic bifunctional protein OS=Oryctolagus cuniculus OX=9986 GN=H6PD PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0009253 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01182 all species → | Glucosamine_iso | Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase | Domain | Interproscan |
| PF00479 all species → | G6PD_N | Glucose-6-phosphate dehydrogenase, NAD binding domain | Domain | Interproscan |
| PF02781 all species → | G6PD_C | Glucose-6-phosphate dehydrogenase, C-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001282 all species → | Family | Glucose-6-phosphate dehydrogenase | Interproscan |
| IPR006148 all species → | Domain | Glucosamine/galactosamine-6-phosphate isomerase | Interproscan |
| IPR037171 all species → | Homologous_superfamily | NagB/RpiA transferase-like | Interproscan |
| IPR005900 all species → | Domain | 6-phosphogluconolactonase, DevB-type | Interproscan |
| IPR036291 all species → | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| IPR022674 all species → | Domain | Glucose-6-phosphate dehydrogenase, NAD-binding | Interproscan |
| IPR022675 all species → | Domain | Glucose-6-phosphate dehydrogenase, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23429 all species → | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006006 all species → | Biological Process | glucose metabolic process | Interproscan |
| GO:0016614 all species → | Molecular Function | oxidoreductase activity, acting on CH-OH group of donors | Interproscan |
| GO:0050661 all species → | Molecular Function | NADP binding | Interproscan |
| GO:0004345 all species → | Molecular Function | glucose-6-phosphate dehydrogenase activity | Interproscan |
| GO:0005783 all species → | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0009051 all species → | Biological Process | pentose-phosphate shunt, oxidative branch | Interproscan |
| GO:0005975 all species → | Biological Process | carbohydrate metabolic process | Interproscan |
| GO:0006098 all species → | Biological Process | pentose-phosphate shunt | Interproscan |
| GO:0017057 all species → | Molecular Function | 6-phosphogluconolactonase activity | Interproscan |
ENSBQFP00000041262.1.Transcript abundance of ENSBQFP00000041262.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Whole coral | 17 | 9 | 1.33 | 3.52 | |
| polyp and skeleton · 31C, 3week | 6 | 6 | 6.70 | 12.59 | |
| polyp and skeleton · 28C, 3week | 6 | 4 | 4.12 | 9.27 | |
| polyp and skeleton · 26C, 3week | 4 | 2 | 3.15 | 8.55 | |
| polyp and skeleton · 28C, 24hr | 2 | 2 | 5.15 | 6.25 | |
| polyp and skeleton · 31C, 24hr | 2 | 1 | 4.20 | 8.41 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| ERR6178770 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 3.52 |
| ERR6178781 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 3.01 |
| ERR6178776 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 2.91 |
| ERR6178780 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 2.82 |
| ERR6178783 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 2.62 |
| ERR6178778 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 2.18 |
| ERR6178389 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 2.11 |
| ERR6178779 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 1.95 |
| ERR6178773 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 1.50 |
| ERR6178387 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| ERR6178388 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| ERR6178771 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| ERR6178772 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| ERR6178774 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| ERR6178775 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| ERR6178777 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| ERR6178782 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 0.00 |
| SRR12578066 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 12.59 |
| SRR12587804 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 9.05 |
| SRR12578068 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 6.41 |
| SRR12587800 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 6.00 |
| SRR12587799 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 3.30 |
| SRR12578065 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 2.84 |
| SRR12587802 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 9.27 |
| SRR12587808 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 7.12 |
| SRR12587807 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 4.50 |
| SRR12587803 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 3.85 |
| SRR12578067 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 0.00 |
| SRR5949849 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 0.00 |
| SRR12587798 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 8.55 |
| SRR12587805 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 4.06 |
| SRR12587801 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 0.00 |
| SRR12587806 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 0.00 |
| SRR12578063 | polyp and skeleton · 28C, 24hr | polyp and skeleton | not recorded | 28C, 24hr | SRP115860 | 6.25 |
| SRR5949850 | polyp and skeleton · 28C, 24hr | polyp and skeleton | not recorded | 28C, 24hr | SRP115860 | 4.04 |
| SRR12578064 | polyp and skeleton · 31C, 24hr | polyp and skeleton | not recorded | 31C, 24hr | SRP115860 | 8.41 |
| SRR5949848 | polyp and skeleton · 31C, 24hr | polyp and skeleton | not recorded | 31C, 24hr | SRP115860 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (HCOER_TPM,
StringTie quantification over 37 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 38 | ENSBQFP00000016295 | 0.939778825341269 |
| Negatively correlated | 5 | ENSBQFP00000041514 | -0.701357790261154 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000041262, the spelling this network uses.
Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
