Gene detail

Detailed information of ENSBQFP00000041514 in Heliopora coerulea

Genomic Location: JASJOG010000252.1:345576...359585
NR annotation: CAB4003232.1, catenin beta-like [Paramuricea clavata]
Species Heliopora coerulea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSBQFT00000046662

ATGTCAAACTACACCCATACTAGTGCTCCTCATTATGGCAATCAAATGACCAAAGAGGGTCAGAATGCAATGTGGTACCAGCAACACCCATACAATCCAGACTCAGGTATACAGAGTGAGCTCAATACAGCTCCACCTTCTGTGCATGGGGATGAAGAAAACTTGATGTCTACCTTGGATCAGGAGTTTAATCCACAGGGGATGGACATGAATGAACAGTTCGCCACATCAAGAAGTTTGCGTATTCGCCAGGCGATGTTTCCTGAAACAATGGAGGATGGAtcaaatgttccaattccacagTTGGATCCCACAGCAAATACAGCTGTTCAACGTTTGTCTCAGCCATCACAAATGGTCAAGAATGCTGTTGTTGATCTTATTAATTATCAGGATGATGCAGATGTGGCTACAAGAGCTATTCCAGAATTGACCAGATTGCTAAGTGACAATGACCGAACTGTTGTTAGCAATGCAGCAACAATGGTCCATCAGTTGTCAAAAAAAGAAGCTAGCCGCCATGCAGTAGCCAACTCTCCACAGTTAATGGTGTCACTTGTGAGACTCATGGACTCCTCTGGAGATGTTGAGACTGTCCGTTCAATTGCTGGAACATTGCACAACATCTCAAACAACAGACAAGGGTTGCTGTCAATTTTCAAATCTGGAGGCATACCTGCTTTAGTTAAAATGTTAGGATCATCAGTTGAATCCATTGTCTTTTATGCCATTACAACACTTcataatttgttgttgcaccAGGAAGGTGCAAAAATGGCTGTCCGACTTGCTGGTGGGTTGCAGAAAATGGTTGCTCTTCTCCCCAGgacaaatgtaaaatttttagCCATAGTGACTGACTGTCTACATGTCTTGGCTTATGGAAATCAAGAGAGTAAGCTAATCATCTTGGCTTCTGGTGGTCCAGCAGAACTTGTTAGAATAATGAGAACTTACACTTATGAGAAAGTGCTTTTCACAACCAGTAGGGTTTTGAAGGTTTTGTCTGTGTGTTCCAGTAACAAGCCTGCCATTGTGGAGGCCAATGGGATGCAGGTGTTAGCTCAACATCTTGGCTCAAATAGCAACCGTTTGGTTCAGAATTGTTTGTGGACATTGAGAAATATGTCAGATGCTGCCACACGTGTTGATGGCTTGGACAATTTACTTCAAATGTTGATTCAGTTACTATCATCCAATGATGTGCAAGTTGTGACGTGCGCTGCGGGCGTCCTTTCCAATCTGACATGCAACAATCCAAGAAACAAACAAATCGTTTTCAGGGTTGGTGGAGTTGAGGCTTTGGTGAGAACTTGTATACAGGCAGGAGAGAGAGAGGAGATTACAGAACCAGTTGTATGTGCATTACGACATATTACCAGTCGCCATCCAGATGCTGAGGAGGCACAGAACTCTGTTCGGGTTCATTATGGGCTTCCCGTGTTGGTTAAACTCTTGAACCCACCATCGCGTTGGCCATTGATCAAAGCAGTTGTTGGGTTAATCCGAAACTTGGCACTGTGCCCTGCAAACCATGCCGCTATCAGAGAAAATGGTGGCATCCCGAGAATGGTGCAGCTTCTTATGAAAGCTCACCAGGACATCCGAAGAGCTGGTGGACAACCATTTGCTGTTGATGGTGTGCGCATGGAAGACATCGTCGAAGGCACCGTGGGTGCTTTGCATATCTTGGCACGAGAACCAAATAACCGGGCTGTGATCAGAAGTTTGAACGTAATACCATTATTTGTACAGCTGCTTCAGTCAAATATCGAGAACATTCAACGGGTAGCAGCTGGAGTGCTTTGTGAACTATCCCAAGAGAAGGAAGGTGCCGAGGTCATTGAAAACGAGAATGGCACTGGTCCACTCACTGAACTGCTTCGTTCGACAAATGAAGGCATTGCTGCATATGCTGCCGCAGTTCTTTTCCGCATGTCTGAGGATAAACCTCAGGACTACAGGAAACGCCTTTCAGTGGAGTTAAGCTCTCTTTTCAAAGATGACATGCAGATGAACGAGCCGATGAGTGGAGGGCATATGATGGATCCAAGCTATCCGATGGATATGTCCCACATGCAGGGAATGCACCAGCCAGCATATGGTCAACATGGTGGGACTGCTGTTGGCTACCAACAATATGGCCAGCCACAGCAGCATCAGCAATTCATGAATTACGATCCAAGCTATGACTATCCCCCCGCAACAGGTGGCCATCCACCGCCTCCTGGAGCCGGCGATATGCATGGGCAGTGGTTTGACTCTGACTTGTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P35224	Catenin beta OS=Urechis caupo OX=6431 PE=2 SV=1
Q7QHW5	Armadillo segment polarity protein OS=Anopheles gambiae OX=7165 GN=arm PE=3 SV=5
Q17GS9	Armadillo segment polarity protein OS=Aedes aegypti OX=7159 GN=arm PE=3 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006397 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00514 all species →	Arm	Armadillo/beta-catenin-like repeat	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR013284 all species →	Family	Beta-catenin	Interproscan
IPR000225 all species →	Repeat	Armadillo	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45976 all species →	ARMADILLO SEGMENT POLARITY PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0007155 all species →	Biological Process	cell adhesion	Interproscan
GO:0045296 all species →	Molecular Function	cadherin binding	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0003713 all species →	Molecular Function	transcription coactivator activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005912 all species →	Cellular Component	adherens junction	Interproscan
GO:0016342 all species →	Cellular Component	catenin complex	Interproscan
GO:0019903 all species →	Molecular Function	protein phosphatase binding	Interproscan
GO:0035257 all species →	Molecular Function	nuclear receptor binding	Interproscan
GO:0045294 all species →	Molecular Function	alpha-catenin binding	Interproscan
GO:0045944 all species →	Biological Process	positive regulation of transcription by RNA polymerase II	Interproscan
GO:0060070 all species →	Biological Process	canonical Wnt signaling pathway	Interproscan
GO:0098609 all species →	Biological Process	cell-cell adhesion	Interproscan
GO:0140297 all species →	Molecular Function	DNA-binding transcription factor binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K02105	CTNNB1; catenin beta 1	-	Cushing syndrome	ko04934	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000041514 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples

37TPM > 0

6Conditions

1,051.3Max TPM

617.8Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
Whole coral	17	17	803.55	1,051.29
polyp and skeleton · 31C, 3week	6	6	307.13	415.93
polyp and skeleton · 28C, 3week	6	6	629.47	902.24
polyp and skeleton · 26C, 3week	4	4	582.20	846.08
polyp and skeleton · 28C, 24hr	2	2	370.65	377.22
polyp and skeleton · 31C, 24hr	2	2	253.52	290.17

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
ERR6178775	Whole coral	Whole coral	not recorded	not recorded	ERP120267	1,051.29
ERR6178783	Whole coral	Whole coral	not recorded	not recorded	ERP120267	920.69
ERR6178388	Whole coral	Whole coral	not recorded	not recorded	ERP120267	902.98
ERR6178780	Whole coral	Whole coral	not recorded	not recorded	ERP120267	894.65
ERR6178773	Whole coral	Whole coral	not recorded	not recorded	ERP120267	873.65
ERR6178781	Whole coral	Whole coral	not recorded	not recorded	ERP120267	868.50
ERR6178771	Whole coral	Whole coral	not recorded	not recorded	ERP120267	860.91
ERR6178778	Whole coral	Whole coral	not recorded	not recorded	ERP120267	823.91
ERR6178774	Whole coral	Whole coral	not recorded	not recorded	ERP120267	798.77
ERR6178389	Whole coral	Whole coral	not recorded	not recorded	ERP120267	780.84
ERR6178782	Whole coral	Whole coral	not recorded	not recorded	ERP120267	746.44
ERR6178387	Whole coral	Whole coral	not recorded	not recorded	ERP120267	746.06
ERR6178776	Whole coral	Whole coral	not recorded	not recorded	ERP120267	738.65
ERR6178772	Whole coral	Whole coral	not recorded	not recorded	ERP120267	682.11
ERR6178770	Whole coral	Whole coral	not recorded	not recorded	ERP120267	676.03
ERR6178777	Whole coral	Whole coral	not recorded	not recorded	ERP120267	671.70
ERR6178779	Whole coral	Whole coral	not recorded	not recorded	ERP120267	623.10
SRR12587800	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	415.93
SRR12587804	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	360.75
SRR12587799	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	343.33
SRR12578065	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	340.68
SRR12578068	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	260.28
SRR12578066	polyp and skeleton · 31C, 3week	polyp and skeleton	not recorded	31C, 3week	SRP115860	121.80
SRR5949849	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	902.24
SRR12578067	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	797.02
SRR12587808	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	606.75
SRR12587803	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	593.48
SRR12587802	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	468.58
SRR12587807	polyp and skeleton · 28C, 3week	polyp and skeleton	not recorded	28C, 3week	SRP115860	408.75
SRR12587806	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	846.08
SRR12587801	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	577.01
SRR12587805	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	491.12
SRR12587798	polyp and skeleton · 26C, 3week	polyp and skeleton	not recorded	26C, 3week	SRP115860	414.57
SRR5949850	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	377.22
SRR12578063	polyp and skeleton · 28C, 24hr	polyp and skeleton	not recorded	28C, 24hr	SRP115860	364.08
SRR5949848	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	290.17
SRR12578064	polyp and skeleton · 31C, 24hr	polyp and skeleton	not recorded	31C, 24hr	SRP115860	216.87

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	29	ENSBQFP00000001428	0.873339252153636
Negatively correlated	921	ENSBQFP00000023592	-0.873244310641193

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →