Genomic Location: JASJOG010000192.1:104958...161971
NR annotation: XP_028402314.1, talin-1-like isoform X1 [Dendronephthya gigantea]
Species Heliopora coerulea · all data for this species · gene families
| CDS |
| ENSBQFT00000047305 |
| Protein |
| ENSBQFP00000042053.1 |
| UniProt accession | Description |
|---|---|
| A0A3G2LGI8 | Talin OS=Oscarella pearsei OX=1940113 GN=TLN PE=1 SV=1 |
| P54939 | Talin-1 OS=Gallus gallus OX=9031 GN=TLN1 PE=1 SV=2 |
| Q9Y4G6 | Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001942 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21692 all species → | Talin_R4 | Talin, R4 domain | Domain | Interproscan |
| PF00373 all species → | FERM_M | FERM central domain | Domain | Interproscan |
| PF09141 all species → | Talin_middle | Talin, middle domain | Domain | Interproscan |
| PF08913 all species → | VBS | Vinculin Binding Site | Domain | Interproscan |
| PF16511 all species → | FERM_f0 | N-terminal or F0 domain of Talin-head FERM | Domain | Interproscan |
| PF01608 all species → | I_LWEQ | I/LWEQ domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR049108 all species → | Domain | Talin, R4 domain | Interproscan |
| IPR036723 all species → | Homologous_superfamily | Alpha-catenin/vinculin-like superfamily | Interproscan |
| IPR035964 all species → | Homologous_superfamily | I/LWEQ domain superfamily | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR019748 all species → | Domain | FERM central domain | Interproscan |
| IPR019747 all species → | Conserved_site | FERM conserved site | Interproscan |
| IPR015224 all species → | Domain | Talin, central | Interproscan |
| IPR014352 all species → | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR037438 all species → | Domain | Talin-1/2, rod-segment | Interproscan |
| IPR015009 all species → | Domain | Vinculin-binding site-containing domain | Interproscan |
| IPR035963 all species → | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR032425 all species → | Domain | Talin, N-terminal F0 domain | Interproscan |
| IPR036476 all species → | Homologous_superfamily | Talin, central domain superfamily | Interproscan |
| IPR002558 all species → | Domain | I/LWEQ domain | Interproscan |
| IPR019749 all species → | Domain | Band 4.1 domain | Interproscan |
| IPR000299 all species → | Domain | FERM domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR19981 all species → | TALIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0007155 all species → | Biological Process | cell adhesion | Interproscan |
| GO:0051015 all species → | Molecular Function | actin filament binding | Interproscan |
| GO:0003779 all species → | Molecular Function | actin binding | Interproscan |
| GO:0005178 all species → | Molecular Function | integrin binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0005925 all species → | Cellular Component | focal adhesion | Interproscan |
| GO:0098609 all species → | Biological Process | cell-cell adhesion | Interproscan |
| GO:0001726 all species → | Cellular Component | ruffle | Interproscan |
| GO:0005200 all species → | Molecular Function | structural constituent of cytoskeleton | Interproscan |
| GO:0005856 all species → | Cellular Component | cytoskeleton | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06271 | TLN; talin | - | Exosome | ko04147 | deepkoala |
Transcript abundance of ENSBQFP00000042053.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Whole coral | 17 | 17 | 105.32 | 184.15 | |
| polyp and skeleton · 31C, 3week | 6 | 6 | 138.97 | 223.80 | |
| polyp and skeleton · 28C, 3week | 6 | 6 | 208.77 | 274.50 | |
| polyp and skeleton · 26C, 3week | 4 | 4 | 169.58 | 219.37 | |
| polyp and skeleton · 28C, 24hr | 2 | 2 | 174.54 | 185.71 | |
| polyp and skeleton · 31C, 24hr | 2 | 2 | 127.55 | 131.96 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| ERR6178781 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 184.15 |
| ERR6178778 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 159.55 |
| ERR6178770 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 137.74 |
| ERR6178774 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 133.34 |
| ERR6178783 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 121.37 |
| ERR6178773 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 112.48 |
| ERR6178775 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 104.32 |
| ERR6178389 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 103.83 |
| ERR6178388 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 103.39 |
| ERR6178776 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 99.38 |
| ERR6178782 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 92.86 |
| ERR6178771 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 81.90 |
| ERR6178777 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 74.86 |
| ERR6178772 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 74.72 |
| ERR6178387 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 74.10 |
| ERR6178780 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 67.15 |
| ERR6178779 | Whole coral | Whole coral | not recorded | not recorded | ERP120267 | 65.20 |
| SRR12578065 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 223.80 |
| SRR12587804 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 174.56 |
| SRR12578068 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 138.44 |
| SRR12587800 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 122.39 |
| SRR12587799 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 94.32 |
| SRR12578066 | polyp and skeleton · 31C, 3week | polyp and skeleton | not recorded | 31C, 3week | SRP115860 | 80.33 |
| SRR12578067 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 274.50 |
| SRR12587803 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 229.02 |
| SRR12587802 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 221.57 |
| SRR12587808 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 213.00 |
| SRR5949849 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 190.34 |
| SRR12587807 | polyp and skeleton · 28C, 3week | polyp and skeleton | not recorded | 28C, 3week | SRP115860 | 124.17 |
| SRR12587801 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 219.37 |
| SRR12587806 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 174.05 |
| SRR12587798 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 145.02 |
| SRR12587805 | polyp and skeleton · 26C, 3week | polyp and skeleton | not recorded | 26C, 3week | SRP115860 | 139.88 |
| SRR5949850 | polyp and skeleton · 28C, 24hr | polyp and skeleton | not recorded | 28C, 24hr | SRP115860 | 185.71 |
| SRR12578063 | polyp and skeleton · 28C, 24hr | polyp and skeleton | not recorded | 28C, 24hr | SRP115860 | 163.37 |
| SRR12578064 | polyp and skeleton · 31C, 24hr | polyp and skeleton | not recorded | 31C, 24hr | SRP115860 | 131.96 |
| SRR5949848 | polyp and skeleton · 31C, 24hr | polyp and skeleton | not recorded | 31C, 24hr | SRP115860 | 123.15 |
Source: CnidoSite RNA-seq expression matrices (HCOER_TPM,
StringTie quantification over 37 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 17 | ENSBQFP00000052032 | 0.815536443231252 |
| Negatively correlated | 31 | ENSBQFP00000027670 | -0.817701781911293 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000042053, the spelling this network uses.
Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
