Detailed information of ENSBQFP00000045776.1 in Heliopora coerulea

Genomic Location: JASJOG010000254.1:159700...163653
NR annotation: XP_046843873.1, peroxiredoxin-6-like isoform X2 [Xenia sp. Carnegie-2017]
Species Heliopora coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q5ZJF4Peroxiredoxin-6 OS=Gallus gallus OX=9031 GN=PRDX6 PE=2 SV=3
P30041Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3
O35244Peroxiredoxin-6 OS=Rattus norvegicus OX=10116 GN=Prdx6 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004477 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF10417
all species →		1-cysPrx_CC-terminal domain of 1-Cys peroxiredoxinDomainInterproscan
PF00578
all species →		AhpC-TSAAhpC/TSA familyDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR045020
all species →		Family1-Cys peroxiredoxinInterproscan
IPR013766
all species →		DomainThioredoxin domainInterproscan
IPR019479
all species →		DomainPeroxiredoxin, C-terminalInterproscan
IPR000866
all species →		DomainAlkyl hydroperoxide reductase subunit C/ Thiol specific antioxidantInterproscan
IPR036249
all species →		Homologous_superfamilyThioredoxin-like superfamilyInterproscan
IPR024706
all species →		FamilyPeroxiredoxin, AhpC-typeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43503
all species →		MCG48959-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0051920
all species →		Molecular Functionperoxiredoxin activityInterproscan
GO:0098869
all species →		Biological Processcellular oxidant detoxificationInterproscan
GO:0016209
all species →		Molecular Functionantioxidant activityInterproscan
GO:0016491
all species →		Molecular Functionoxidoreductase activityInterproscan
GO:0005739
all species →		Cellular ComponentmitochondrionInterproscan
GO:0005829
all species →		Cellular ComponentcytosolInterproscan
GO:0045454
all species →		Biological Processcell redox homeostasisInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11188PRDX6; peroxiredoxin 6EC:1.11.1.7
EC:1.11.1.27
EC:3.1.1.-
Phenylpropanoid biosynthesisko00940deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of ENSBQFP00000045776.1 across 37 RNA-seq samples of Heliopora coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

37Samples
35TPM > 0
6Conditions
1,018.4Max TPM
434.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Whole coral 17 17 629.73 1,018.45
polyp and skeleton · 31C, 3week 6 6 225.87 303.41
polyp and skeleton · 28C, 3week 6 5 253.47 416.31
polyp and skeleton · 26C, 3week 4 3 347.82 664.61
polyp and skeleton · 28C, 24hr 2 2 291.63 308.13
polyp and skeleton · 31C, 24hr 2 2 253.27 256.08

Per sample · hover a bar for the full sample record

Show the sample table (37 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR6178783 Whole coral Whole coral not recorded not recorded ERP120267 1,018.45
ERR6178778 Whole coral Whole coral not recorded not recorded ERP120267 826.40
ERR6178782 Whole coral Whole coral not recorded not recorded ERP120267 775.33
ERR6178771 Whole coral Whole coral not recorded not recorded ERP120267 762.16
ERR6178772 Whole coral Whole coral not recorded not recorded ERP120267 759.72
ERR6178770 Whole coral Whole coral not recorded not recorded ERP120267 714.87
ERR6178777 Whole coral Whole coral not recorded not recorded ERP120267 709.86
ERR6178774 Whole coral Whole coral not recorded not recorded ERP120267 598.32
ERR6178776 Whole coral Whole coral not recorded not recorded ERP120267 580.76
ERR6178388 Whole coral Whole coral not recorded not recorded ERP120267 566.57
ERR6178780 Whole coral Whole coral not recorded not recorded ERP120267 537.08
ERR6178781 Whole coral Whole coral not recorded not recorded ERP120267 535.94
ERR6178775 Whole coral Whole coral not recorded not recorded ERP120267 528.57
ERR6178773 Whole coral Whole coral not recorded not recorded ERP120267 509.70
ERR6178389 Whole coral Whole coral not recorded not recorded ERP120267 481.19
ERR6178387 Whole coral Whole coral not recorded not recorded ERP120267 435.61
ERR6178779 Whole coral Whole coral not recorded not recorded ERP120267 364.91
SRR12578065 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 303.41
SRR12587799 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 245.04
SRR12578066 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 230.20
SRR12587804 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 220.79
SRR12587800 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 209.89
SRR12578068 polyp and skeleton · 31C, 3week polyp and skeleton not recorded 31C, 3week SRP115860 145.87
SRR12587803 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 416.31
SRR12587808 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 367.62
SRR5949849 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 283.10
SRR12587807 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 246.31
SRR12587802 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 207.46
SRR12578067 polyp and skeleton · 28C, 3week polyp and skeleton not recorded 28C, 3week SRP115860 0.00
SRR12587806 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 664.61
SRR12587798 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 465.79
SRR12587805 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 260.89
SRR12587801 polyp and skeleton · 26C, 3week polyp and skeleton not recorded 26C, 3week SRP115860 0.00
SRR5949850 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 308.13
SRR12578063 polyp and skeleton · 28C, 24hr polyp and skeleton not recorded 28C, 24hr SRP115860 275.14
SRR5949848 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 256.08
SRR12578064 polyp and skeleton · 31C, 24hr polyp and skeleton not recorded 31C, 24hr SRP115860 250.45

Source: CnidoSite RNA-seq expression matrices (HCOER_TPM, StringTie quantification over 37 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Heliopora coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated14ENSBQFP000000478350.874807524471332
Negatively correlated9ENSBQFP00000013805-0.776121868621963

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list. Partner counts were matched on ENSBQFP00000045776, the spelling this network uses.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Heliopora coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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