Gene detail

Detailed information of ENSCIQP00000004006.1 in Millepora alcicornis

Genomic Location: chr11:147389267...147412148
NR annotation: XP_047146816.1, EF-hand calcium-binding domain-containing protein 7 [Hydra vulgaris]
Species Millepora alcicornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSCIQT00000004604

tttagtCTCTCAAAAATAAATGTCTTCCAGAAACAAAAGTACTACTGGCAGCACCAGAAAAGTTTTATCTCCGAAAAAAGAGAGCCATGCATTACATGAAAACGAATTGAAATCAGTGTATTTGACAGTTTTCCAAagtacaaaagaagaaataacaacACAAGACGAACTATTATTATTGTTACAGTATGCGGGTTGCAATCCATCAAAGAAAGTTCTGCAAAAGTTCTGGGGACCTAAGACAGACTCGATCTCGTTCCAACAGTTCTGTTCAATCGTCGATCAAGTGTCTCAAACATCCAAACAAGATTTGTTGAAAGCGTTTCGCAAGATTGACGTCAACGGGGATGGTTTCATTACGCACGATGAATTGTTCAAAGTACTTACAAAGCGAGGCGAAAGAATGACAAAGCAAGAAGTGAAGACAATGATAGAGGATGCAGACTGCAACGGAGACAGTAAGCTCGACTACCATGAGttttgcgCATTGATGGATTCAACAATCAGTAAATGTAAAAAGCTCTACTCTACCAGCacttatgaaaatgaaaacgagCGTTCAACCAAAAGCAGTAAAAGCAGAACATCGTTGATCGAGTCTTCAGTTTCAAAGACACCTCCAGCGAAGCAAAGTGCTTTTTCTAAATCCCAGTTTGATGAAAAACGTTCTTCTAGTTTAGAatctattaaagaaaatacttcaAGGTCTCAAGATAGAAAAAAGCAGTCAATAACATCGAAATTGTcgatgaaaaaagaagaagaaaaattacatttgaaataCGAGAAACTGACGTCAGAGCCACCAGATTTGAATCGCTGGCATTTTCATTCGATCAAAGGTTCCTTTTACAAAGAAGATGATGGCATAATCGAAAGTCATTCTTACGAATTGAAAATAATGCAACCTACGCGTTTGTGGATGTCTGTCAAAACTATCGCTCCTAAATATGGTAAATTCTACAACAATATACTTAATATTGATACCACAATCTACCTACTCGATAATCAATCACGGTTGGTGGCTTTTTCAAACTCCATTGTTGAAGATAGATCCTGCCTTCAGTGTGAAGTTGACATTGGTGTTTATACGGTTTATGTATTCTCAAGTGGTGCTCAGTTGCTTTCAGACAGTAGTGGCAGTGGAGAACTGACCATTGTCAAGGGATCTGGAGATGAAGCACGGTTAACGAAAGCTTGCAAAGACACCCTGATGGAGATATTCTATCGTTGTGACTTGAATGGTAATGGTTACCTCAGTAGAGAAGAatttgacatatttcaaaaaaggacCAGTGGAGAAGAGTGTGATGATGCAGCATGGCAAGTTGTTCAAGAAAATTGTGATGTAACGCCACAAATGGAACTAACACCCAGAGGATTTATCGAATTGAACTTGATGGAGGCATGTGACCCAGAAGGAGGACAGGATGAATTATGGGTGACATTAGAAAGTATGGGATACTCAAGAACTCTACAACTGGCAAAGGGTTGTCCGTTCCAGTTGGAAGTCTTCACCAAACAGTCAGATCACGAGGTGTCAGCGGTTGATGTCAGCGGTGTGAACAAAGAGTTAGAGCAAGCCTTGCATGAATCTATATCAATGATctcaaagaaaactttaataaaaaataagaaagatttgATTCTGCATGTGGCAGAATTTGATCAAAGGATTTCATTAGCCATTGAGAATCAgTCTCACAAGGCTGTCAGTGTGATTGTGGATTGTAATGGTAGTGAGAACTTGATGTCTGATAAAGGTTCATTACGTCATTCTGTCGATGTGGAGCCGAAGACAGTGAAGGTGATCCATCATTTGGTACCAGAGAACAAGAATCATGGTGTAAAACTTGATCACAAGGAAACTATCTCCAGTTAAttcatttcagaagcagttcCCTGGAGTTGTTCCGTTGACAAGAtttatgtaaagattttgaaaattttcaggaaacatcCCCGATTTAGTCTTATTTTaggtaaaaagagactccatcacaagtaTTTCCTGTTAAGTTTGCGAAATGTCTCATACCAATTCGCAAATCATcctaaaaataggtgttcttaaaaatttcgtaagtGTCAGAGTCTATTTtgtggtaaagttgcaggcttgaggcctgcaagattattaaaaaagagacatcgGCACaagtgtcttcctgtgaattttgcaaaattttaacgAACAGTATagctccgggcaactgcttctgaacacCCGTAAACTGTTGCTACTGCCATTTGATTTGCCGACATGTTCACCAAACTCACTCGacaactttttcaatgaaatcgtTGTATTAGaagtaaattatttgaagaatcatttcattattttgttatgaGACATTATTTTAACAGACTCAAGCCGCGCAAGGTTACTTAGAATTTGTAAATATCTTGAATTGGATTTCATGTAAATAAACGTAATTTATTGAACAAACGCGAAAGAAAACGAACAAGTGAACTAGCACATTTGATTGGAAAAGAGTGCTTACTTTGAAACAATCAGTGCACTTTTGTTATCAGTAATTTTGGAAAAAGGAACTAGCCCTCAGAAgcaaaaattttaagcaactttgtAACGATGGTCCTAGATAACGAATACTTGAAAGAAAATGatactaaaatttcaaaagattcgagaacaaattttacatatgaagcagtttttgattttaagaagaatttaacattcattaattaaac

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6DCF6	EF-hand calcium-binding domain-containing protein 7 OS=Xenopus laevis OX=8355 GN=efcab7 PE=2 SV=1
Q8VDY4	EF-hand calcium-binding domain-containing protein 7 OS=Mus musculus OX=10090 GN=Efcab7 PE=1 SV=1
A8K855	EF-hand calcium-binding domain-containing protein 7 OS=Homo sapiens OX=9606 GN=EFCAB7 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005216 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13202 all species →	EF-hand_5	EF hand	Domain	Interproscan
PF13499 all species →	EF-hand_7	EF-hand domain pair	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR018247 all species →	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR052266 all species →	Family	Mitochondrial Rho GTPase/EF-hand domain-containing protein	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46819 all species →	EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0060170 all species →	Cellular Component	ciliary membrane	Interproscan
GO:0098797 all species →	Cellular Component	plasma membrane protein complex	Interproscan
GO:1903569 all species →	Biological Process	positive regulation of protein localization to ciliary membrane	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K23852	EFCAB7; EF-hand calcium-binding domain-containing protein 7	-	Cilium and associated proteins	ko03037	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Millepora alcicornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Millepora alcicornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →