Genomic Location: :...
NR annotation: XP_047140440.1, ras-specific guanine nucleotide-releasing factor 1-like isoform X2 [Hydra vulgaris]
| CDS | |||||
| ENSDJXT00000056398 | |||||
| Transcript |
| ENSDJXT00000056398 |
| Protein |
| ENSDJXP00000048963.1 |
| Uniprot term | Description |
|---|---|
| A2CEA7 | Ras-specific guanine nucleotide-releasing factor 2 OS=Danio rerio OX=7955 GN=rasgrf2 PE=3 SV=1 |
| Q99JE4 | Ras-specific guanine nucleotide-releasing factor 2 OS=Rattus norvegicus OX=10116 GN=Rasgrf2 PE=1 SV=1 |
| O14827 | Ras-specific guanine nucleotide-releasing factor 2 OS=Homo sapiens OX=9606 GN=RASGRF2 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00618 | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| PF00621 | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF00169 | PH | PH domain | Domain | Interproscan |
| PF00617 | RasGEF | RasGEF domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000651 | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR000219 | Domain | Dbl homology (DH) domain | Interproscan |
| IPR001895 | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR023578 | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR019804 | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| IPR008937 | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR036964 | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR035899 | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04349 | RASGRF1; Ras-specific guanine nucleotide-releasing factor 1 | - | Focal adhesion | ko04510 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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