Genomic Location: :...
NR annotation: CAH3104699.1, unnamed protein product [Pocillopora meandrina]
| CDS | |||||
| ENSDKPT00000004321 | |||||
| Transcript |
| ENSDKPT00000004321 |
| Protein |
| ENSDKPP00000004321.1 |
| Uniprot term | Description |
|---|---|
| Q14191 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2 |
| O93530 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN OS=Xenopus laevis OX=8355 GN=wrn PE=1 SV=1 |
| O09053 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN OS=Mus musculus OX=10090 GN=Wrn PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00270 | DEAD | DEAD/DEAH box helicase | Domain | Interproscan |
| PF16124 | RecQ_Zn_bind | RecQ zinc-binding | Domain | Interproscan |
| PF00271 | Helicase_C | Helicase conserved C-terminal domain | Domain | Interproscan |
| PF14493 | HTH_40 | Helix-turn-helix domain | Domain | Interproscan |
| PF00570 | HRDC | HRDC domain | Domain | Interproscan |
| PF09382 | RQC | RQC domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR014001 | Domain | Helicase superfamily 1/2, ATP-binding domain | Interproscan |
| IPR001650 | Domain | Helicase, C-terminal domain-like | Interproscan |
| IPR011545 | Domain | DEAD/DEAH box helicase domain | Interproscan |
| IPR036390 | Homologous_superfamily | Winged helix DNA-binding domain superfamily | Interproscan |
| IPR036388 | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR004589 | Family | DNA helicase, ATP-dependent, RecQ type | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR044876 | Homologous_superfamily | HRDC domain superfamily | Interproscan |
| IPR018982 | Domain | RQC domain | Interproscan |
| IPR032284 | Domain | ATP-dependent DNA helicase RecQ, zinc-binding domain | Interproscan |
| IPR010997 | Homologous_superfamily | HRDC-like superfamily | Interproscan |
| IPR002121 | Domain | HRDC domain | Interproscan |
| IPR029491 | Domain | Helicase Helix-turn-helix domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13710 | DNA HELICASE RECQ FAMILY MEMBER | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000723 | Biological Process | telomere maintenance | Interproscan |
| GO:0000724 | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005654 | Cellular Component | nucleoplasm | Interproscan |
| GO:0005694 | Cellular Component | chromosome | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0006268 | Biological Process | DNA unwinding involved in DNA replication | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0006310 | Biological Process | DNA recombination | Interproscan |
| GO:0009378 | Molecular Function | four-way junction helicase activity | Interproscan |
| GO:0032508 | Biological Process | DNA duplex unwinding | Interproscan |
| GO:0043138 | Molecular Function | 3'-5' DNA helicase activity | Interproscan |
| GO:0044806 | Biological Process | G-quadruplex DNA unwinding | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0004386 | Molecular Function | helicase activity | Interproscan |
| GO:0006260 | Biological Process | DNA replication | Interproscan |
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0044237 | Biological Process | obsolete cellular metabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10900 | WRN, RECQL2; werner syndrome ATP-dependent helicase | EC:5.6.2.4 | DNA repair and recombination proteins | ko03400 | deepkoala |