Gene detail

Detailed information of ENSDKPP00000024217.1 in Plumapathes pennacea

Genomic Location: :...
NR annotation: XP_020608686.1, hepatocyte growth factor-regulated tyrosine kinase substrate-like [Orbicella faveolata]

Gene Structure

Sequence

Uniprot

Gene family

Uniprot term	Description
Q99LI8	Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Mus musculus OX=10090 GN=Hgs PE=1 SV=2
Q9JJ50	Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Rattus norvegicus OX=10116 GN=Hgs PE=1 SV=1
O14964	Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1

Gene family	Subfamily
Ubiquitin Family	UBD\|Alpha-Helix\|VHS

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01363	FYVE	FYVE zinc finger	Domain	Interproscan
PF00790	VHS	VHS domain	Repeat	Interproscan
PF12210	Hrs_helical	Hepatocyte growth factor-regulated tyrosine kinase substrate	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008942	Homologous_superfamily	ENTH/VHS	Interproscan
IPR011011	Homologous_superfamily	Zinc finger, FYVE/PHD-type	Interproscan
IPR017455	Domain	Zinc finger, FYVE-related	Interproscan
IPR000306	Domain	FYVE zinc finger	Interproscan
IPR017073	Family	Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27	Interproscan
IPR024641	Domain	Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain	Interproscan
IPR002014	Domain	VHS domain	Interproscan
IPR013083	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan
IPR003903	Conserved_site	Ubiquitin interacting motif	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46275	HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0046872	Molecular Function	metal ion binding	Interproscan
GO:0005769	Cellular Component	early endosome	Interproscan
GO:0031623	Biological Process	receptor internalization	Interproscan
GO:0032456	Biological Process	endocytic recycling	Interproscan
GO:0043130	Molecular Function	ubiquitin binding	Interproscan
GO:0035091	Molecular Function	phosphatidylinositol binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K12182	HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate	-	Membrane trafficking	ko04131	deepkoala