Genomic Location: not available for this species
NR annotation: XP_020903595.1, E3 ubiquitin-protein ligase CBL-B-B isoform X2 [Exaiptasia diaphana]
Species abbreviation DLINE · all data for this species · gene families
| CDS |
| ENSDLIT00000002416 |
| Transcript |
| ENSDLIT00000002416 |
| Protein |
| ENSDLIP00000002004.1 |
| UniProt accession | Description |
|---|---|
| Q8K4S7 | E3 ubiquitin-protein ligase CBL-B OS=Rattus norvegicus OX=10116 GN=Cblb PE=1 SV=1 |
| Q6NRE7 | E3 ubiquitin-protein ligase CBL-B-B OS=Xenopus laevis OX=8355 GN=cblb-b PE=2 SV=1 |
| Q13191 | E3 ubiquitin-protein ligase CBL-B OS=Homo sapiens OX=9606 GN=CBLB PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006313 (this species only) |
| Ubiquitin family | E3|E3 activity RING|RING · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02761 all species → | Cbl_N2 | CBL proto-oncogene N-terminus, EF hand-like domain | Domain | Interproscan |
| PF02262 all species → | Cbl_N | CBL proto-oncogene N-terminal domain 1 | Domain | Interproscan |
| PF13920 all species → | zf-C3HC4_3 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| PF02762 all species → | Cbl_N3 | CBL proto-oncogene N-terminus, SH2-like domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR014741 all species → | Domain | Adaptor protein Cbl, EF hand-like | Interproscan |
| IPR024162 all species → | Family | Adaptor protein Cbl | Interproscan |
| IPR001841 all species → | Domain | Zinc finger, RING-type | Interproscan |
| IPR003153 all species → | Domain | Adaptor protein Cbl, N-terminal helical | Interproscan |
| IPR036860 all species → | Homologous_superfamily | SH2 domain superfamily | Interproscan |
| IPR024159 all species → | Domain | Adaptor protein Cbl, PTB domain | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR017907 all species → | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR036537 all species → | Homologous_superfamily | Adaptor protein Cbl, N-terminal domain superfamily | Interproscan |
| IPR011992 all species → | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR014742 all species → | Domain | Adaptor protein Cbl, SH2-like domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23007 all species → | CBL | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0007175 all species → | Biological Process | negative regulation of epidermal growth factor-activated receptor activity | Interproscan |
| GO:0017124 all species → | Molecular Function | SH3 domain binding | Interproscan |
| GO:0023051 all species → | Biological Process | regulation of signaling | Interproscan |
| GO:0030971 all species → | Molecular Function | receptor tyrosine kinase binding | Interproscan |
| GO:0045121 all species → | Cellular Component | membrane raft | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0007166 all species → | Biological Process | cell surface receptor signaling pathway | Interproscan |
| GO:0001784 all species → | Molecular Function | phosphotyrosine residue binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K04707 | CBL; E3 ubiquitin-protein ligase CBL | EC:2.3.2.27 | Ubiquitin system | ko04121 | deepkoala |
