Genomic Location: chr1:31502782...31545827
NR annotation: XP_020904542.2, tensin-1 isoform X1 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families
| CDS |
| ENSDLIT00000005587 |
| Transcript |
| ENSDLIT00000005587 |
| Protein |
| ENSDLIP00000005142.1 |
| UniProt accession | Description |
|---|---|
| Q68CZ2 | Tensin-3 OS=Homo sapiens OX=9606 GN=TNS3 PE=1 SV=2 |
| Q5SSZ5 | Tensin-3 OS=Mus musculus OX=10090 GN=Tns3 PE=1 SV=1 |
| Q9HBL0 | Tensin-1 OS=Homo sapiens OX=9606 GN=TNS1 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001591 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00130 all species → | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| PF00102 all species → | Y_phosphatase | Protein-tyrosine phosphatase | Domain | Interproscan |
| PF00017 all species → | SH2 | SH2 domain | Domain | Interproscan |
| PF10409 all species → | PTEN_C2 | C2 domain of PTEN tumour-suppressor protein | Domain | Interproscan |
| PF08416 all species → | PTB | Phosphotyrosine-binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR046349 all species → | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| IPR016130 all species → | Active_site | Protein-tyrosine phosphatase, active site | Interproscan |
| IPR000980 all species → | Domain | SH2 domain | Interproscan |
| IPR002219 all species → | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR035892 all species → | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR036860 all species → | Homologous_superfamily | SH2 domain superfamily | Interproscan |
| IPR013087 all species → | Domain | Zinc finger C2H2-type | Interproscan |
| IPR029023 all species → | Domain | Tensin-type phosphatase domain | Interproscan |
| IPR033929 all species → | Domain | Tensin, phosphotyrosine-binding domain | Interproscan |
| IPR014020 all species → | Domain | Tensin phosphatase, C2 domain | Interproscan |
| IPR000242 all species → | Domain | Tyrosine-specific protein phosphatase, PTPase domain | Interproscan |
| IPR003595 all species → | Domain | Protein-tyrosine phosphatase, catalytic | Interproscan |
| IPR029021 all species → | Homologous_superfamily | Protein-tyrosine phosphatase-like | Interproscan |
| IPR051484 all species → | Family | Tensin Phosphatase | Interproscan |
| IPR000387 all species → | Domain | Tyrosine-specific protein phosphatases domain | Interproscan |
| IPR013625 all species → | Domain | Tensin/EPS8 phosphotyrosine-binding domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45734 all species → | TENSIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0016311 all species → | Biological Process | dephosphorylation | Interproscan |
| GO:0004725 all species → | Molecular Function | protein tyrosine phosphatase activity | Interproscan |
| GO:0006470 all species → | Biological Process | protein dephosphorylation | Interproscan |
| GO:0005925 all species → | Cellular Component | focal adhesion | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K18080 | TNS; tensin | - | Protein phosphatases and associated proteins | ko01009 | deepkoala |
Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |