Gene detail

Detailed information of ENSDLIP00000005391.1 in Diadumene lineata

Genomic Location: chr1:16697318...16705533
NR annotation: KXJ16535.1, Histone acetyltransferase type B catalytic subunit [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSDLIT00000005838

agggatataggggataacaagggatatatgggataattAGGGATATAGTGGATATAGTATAGCTATAGCTATCGTATTATAAATAAGGCCTTTTGATACACTTGGTGCTGCATACACCAAGTACTTACCCTCTCGTCCCAGATTTGGCGCGAAGCAGCTCAAAATGGCTGACTTACAAATGGCCGCTGCGGAGGATTTTCTTGCAGCATACAGATGCAGTGCAAACACTGCAGTTTGCTTCAAATTAGTGAATGAAGAGAAAGATGTATTTGACAAGGACAAGGTGTTTCATCCTGAGTTTACTCATCAATTCTTCGGTGACAGTGAATCCATCTTTGGTTATAAGGGATTAGAGATCCAGcTACACTGTCATGCAGGCAGTTTGTTGACATATTTAGGGAAGAGCTGTGATAGCGATGTCAATGGGCAACTTGATGGTATTGAGcctGACcctgttttgaaaattgtgTCAGAACAGCTTACAGGAGGTTTTCTAAGCAATCTTGATGAATTTATTGCAAAATTACCATCAGAAAACAGTTTTCGACCAATGGGTGAAATGATTCATTCATATAAAAGAAAGGATGTTGACTATGAAATCTATTCTGCTGATGTGTTTACACCAAAATTCAAGGATTATCACAATAGACTGCAACCATTTGTACTTTGGTTTATTGATGCTGCATCATATATAGATATTGATGATGAGAGGTGGCACTTTTTCCTATTGTATGAAAAGAAGAATGTGTGTGGTGAAGCAAGATACAACATAGCAGGATATGTGACAGTCTATCACTACTATGCATATCCAAATCAAATACGACCAAGAATAGGtcaAATGCTTATTCTTCCACCTTATCAAAAAATGGGACATGGAGCTGAACTTTTACGAGTTGTTGAAGAGCATTATATCAAGGACCCTAAAGTCTTAGATATTACTGttgaagATCCTTCAGATAATTTCCTTCGTCTCAGAGACTTTGTGGATTCATTAGCATGCAGTAAACTTGATTGCTTCTCACCAgaaaatctcaaaaaaggTTTCACAGACACATTAGTCAGTGAAGCtcaaaaaataagaaaaatgaaCAAGCTTCAGTGCCGGAGAGTGTATGAAATACTACGTCTTAAAGCAACTGATAGAAGTAACCCTAAGGAATACAAGGAATACAGGCTGGAAGTGAAAGGAAGACTAAATACTGCATACCAGAAAGAAAAATCAGACTTTGAAAAGTTAAAGAAGTACATATCATCTGAAGAGCTTACTGCTATGGTGCATTTACAATCAGCTAGTGAACGACGCAAACAACTGGAACAAATATATGACGAAGTAGAAACAGGATACCTTAAAACTATCGAAAGACTTGTTGCTAGCTGAATATATCCATGTAGCATGTAAAATAATGCTTCATGCTCTAGAGCAAGTTACACAAACATTGTCTGGACTGCAAATTACGAGGCCAGACAAAACTTGACATGTGTTGGATAAcaactgtttttgtgaaaCAGATAACTGTGAACATTGTACAAATGTATAGAAATgagcttttttaaaaaaaccctttattttgtttgatcaACTGtaatattagagtgcaaatactaaaagtgtacaacataacTACAACTAAATAGTAATTCTgtcgttttcttttgtttaattagtgctatgtactactaaatagtgacgactattgcacacatttagtgtttgcactctagtagtTTATTTAGCCCTGTTAAGAAGAAAACAGAAGAATTTGGAGTCTACTAACATTTATTATTCTGAATCCAATGCAAATCAAACTATTTACATGACTGATTTTGTTTGTGCTTCATAGATGCTTTTGACGAAGTAAAAAGTCACAATGTGATGTGTTGCAACTGTAGCAAGAATgttataataacaataaaggTTGTGCTTGTCCAACTTTGAACCACTGTTGGTATTATTTGGTATCAAGTGAGAACATTTAATGTACTACAATACATACTGAATAGTGTTCACTCAGCGATATGTTGACATAGTCTTTTAGTATGTAAACTGAACAAATGAAATCAAGAATTCAAATGAACGTAGTGGAGAACTGTTGGAAATGGTTTTCAGGATTCTTTGCtctaaatgttttgttgttgttgttatgcatgTACACAATATGCTATGTTTTATAGATTCCTTGCAGTTTGTTGggatgcagctcaacctgaaGGGCAAAAGAacggatttcagctcccaagagaggaaaaagcttttgttttgtcctccagatggggctgctttgacgtcacatgcaagggatctattgCGTTGTAACGTCTTCATATTTCCTGAAGATACCTGAGATTAAATAAATCAagctttattcattcattgttg

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O14929	Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=2
Q8BY71	Histone acetyltransferase type B catalytic subunit OS=Mus musculus OX=10090 GN=Hat1 PE=1 SV=1
Q5M939	Histone acetyltransferase type B catalytic subunit OS=Rattus norvegicus OX=10116 GN=Hat1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004509 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF10394 all species →	Hat1_N	Histone acetyl transferase HAT1 N-terminus	Domain	Interproscan
PF00583 all species →	Acetyltransf_1	Acetyltransferase (GNAT) family	Family	Interproscan
PF21183 all species →	HAT1_C	Histone acetyltransferase type B catalytic subunit, C-terminal	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR019467 all species →	Domain	Histone acetyl transferase HAT1 N-terminal	Interproscan
IPR013523 all species →	Homologous_superfamily	Histone acetyltransferase HAT1, C-terminal	Interproscan
IPR017380 all species →	Family	Histone acetyltransferase type B, catalytic subunit	Interproscan
IPR037113 all species →	Homologous_superfamily	Histone acetyl transferase 1, N-terminal domain superfamily	Interproscan
IPR016181 all species →	Homologous_superfamily	Acyl-CoA N-acyltransferase	Interproscan
IPR000182 all species →	Domain	GNAT domain	Interproscan
IPR048776 all species →	Domain	Histone acetyltransferase type B catalytic subunit, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12046 all species →	HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006325 all species →	Biological Process	chromatin organization	Interproscan
GO:0042393 all species →	Molecular Function	histone binding	Interproscan
GO:0004402 all species →	Molecular Function	histone acetyltransferase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0031509 all species →	Biological Process	subtelomeric heterochromatin formation	Interproscan
GO:0016747 all species →	Molecular Function	acyltransferase activity, transferring groups other than amino-acyl groups	Interproscan
GO:0010485 all species →	Molecular Function	histone H4 acetyltransferase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11303	HAT1, KAT1; histone acetyltransferase 1	EC:2.3.1.48	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →