Genomic Location: chr10:8785589...8802583
NR annotation: XP_020913854.1, E3 ubiquitin-protein ligase UHRF1 isoform X3 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families
| CDS |
| ENSDLIT00000006111 |
| Transcript |
| ENSDLIT00000006111 |
| Protein |
| ENSDLIP00000005661.1 |
| UniProt accession | Description |
|---|---|
| E7EZF3 | E3 ubiquitin-protein ligase UHRF1 OS=Danio rerio OX=7955 GN=uhrf1 PE=1 SV=1 |
| F6UA42 | E3 ubiquitin-protein ligase UHRF1 OS=Xenopus tropicalis OX=8364 GN=uhrf1 PE=3 SV=2 |
| B6CHA3 | E3 ubiquitin-protein ligase UHRF1 OS=Xenopus laevis OX=8355 GN=uhrf1 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001740 (this species only) · gene tree & orthology |
| Ubiquitin family | ULD|UBL|NEDD8 · all ubiquitin genes in this species |
| Ubiquitin family | ULD|UFD/UBQ|UBQ_Other · all ubiquitin genes in this species |
| Ubiquitin family | ULD|UFD/UBQ|UBQ_PIM · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12148 all species → | TTD | Tandem tudor domain within UHRF1 | Domain | Interproscan |
| PF00240 all species → | ubiquitin | Ubiquitin family | Domain | Interproscan |
| PF00628 all species → | PHD | PHD-finger | Domain | Interproscan |
| PF02182 all species → | SAD_SRA | SAD/SRA domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR021991 all species → | Domain | UHRF1, tandem tudor domain | Interproscan |
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR045134 all species → | Family | UHRF1/2-like | Interproscan |
| IPR000626 all species → | Domain | Ubiquitin-like domain | Interproscan |
| IPR036987 all species → | Homologous_superfamily | SRA-YDG superfamily | Interproscan |
| IPR003105 all species → | Domain | SRA-YDG | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR001841 all species → | Domain | Zinc finger, RING-type | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR019787 all species → | Domain | Zinc finger, PHD-finger | Interproscan |
| IPR017907 all species → | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR001965 all species → | Domain | Zinc finger, PHD-type | Interproscan |
| IPR015947 all species → | Homologous_superfamily | PUA-like superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14140 all species → | E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0010216 all species → | Biological Process | obsolete negative regulation of gene expression via chromosomal DNA cytosine methylation | Interproscan |
| GO:0016567 all species → | Biological Process | protein ubiquitination | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10638 | UHRF1, NP95; E3 ubiquitin-protein ligase UHRF1 | EC:2.3.2.27 | Chromosome and associated proteins | ko03036 | deepkoala |
Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
