Gene detail

Detailed information of ENSDLIP00000006272.1 in Diadumene lineata

Genomic Location: chr1:12707830...12715228
NR annotation: KXJ13080.1, EF-hand domain-containing family member C2 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSDLIT00000006730

ATGGCGCTTCCTTTCTTACCGGGACAAGTTTTCGACCGAAAACTTGGTAAAACTAAATTTCACAAAACTCATCAGTTTGACTATCGTAATGATGTGTCTTCTTATGTTGGAGAGGCAAAATGTGGAATAGGCGGCGACCCCTTGCCAGGGCAAAAGCTGAGTCCCAAACACAGTGTATTTCCAAAAGGAGTAGGACCAGAAGCACCTTCGTGGGTCGCTTTTGACAGACAAGTTTTATGCTTTGACGCATACTTTCAAGAAGCTGTGCATGAGAAAAGAGAAGAGCAGTATAGGATTAGAAGatgtaaaatatatttctaccTAGAAGATGACAGCATACAAGTTATTGAACCAAAAGTCGAAAATAGTGGAATACCACAAGGAACTCTACTTCGACGTCATCGCATACCTCTTCCTCCTCCTTACGATGAACAGTTTTACACAGTGGAACATTTCAATGTTGGCAaagaaatttcattttattccaAAGTCTTCAAGATTACAGGCTGTGATGAATTCACGCATAACTTCCTCAGAAAACTTGGTGTTAGAGTTAACAACTCATCTAATATCCCAACCGACCCTTATTCTGATCATCGACAAAagTTGGTTGAGAGCATGCAACCTTTGAGACCATATGAAAAGCAAGATACTTTGAAACAGTTCCTACAATATGACCGTCAAGTATTACGTTTCTACTGTCTGTGGGATGATACTGATAGTATGTTTGGTGATGCAAGAGAGATGATACTACACTACTTCCTTGCTGATGATACAGTGGAGATACGTGAAGTGATTCCTGCTAACTCAGGCCGTGATGCTGCACCAATGTTTTTACGCAGACAAAAACTACCTAAGGAACCGGCACAGCTTCGACAGCCTGGAGAGATTACTGGTCGTACTGTATTAAATGTGTTTGGCCCTATGGGTCATGGTGGACGATGGATTCTTGACAGTTTGAAGACTGGTGCAGTGCACACAGACTACTATCTCGACAGTGATCTGACTATTGGATCTTTCATCAATGTTTGGGGAAGAAAGTTCCAGATTTGTGACTGTGATGATTTCACTAAAGACTTTTACAAAACCAAATATGGATTAGATGTGTTTGATTCCATCAAGTACAAGGCTCCACCAGGTGTATTCCCACCTCGTGAAATTCCACCATACAATGGATTTGGTTCAGAGGAAGATTCACTCTGTAACTGCCTCAGTCTTATTCCTAAACCACCTAAGAGAGACTTTAtcaaatttatggaaaaagACAGGGATGGACTTGAGAGTAATGTTCTTCGATTCATGGGTCGTCTCAACACAACTCGCCCTATTGATATGGACAGAAGGTTTATCATTTCCTACTTCCTATCTGATGACACTATCCTGGTCTATGAACCTCAGCAAAGAAATTCAGGAATCCTTGGTGGCAAGTTCTTGGAGAGAAGAAGAATCAAGAGAGACAACCGAGATAATTACTTTTCTGCTCAGGATCTATTCATTGGAGCCCATGTAAATTTCTATAACCATGAGTTTGTCCTGATCGATGCTGATGAATATGCTGTTGACTACATGGAGAATCATCAAGATGAGTTCGTACAAGCCAATATGAGATACATTCTTCCCAAACTAAAGGGAATTGCTGATAATTACTATGAAGAGCTTAAGGCTGTATTCAATGAGCATGATGACAAAGGAACAGGACAGCTAACCTTCAATGCTTTCtggTCCGTCTTAAAGAGGTTTGGTGGCAATCTGACAGAACATGAAATGCTTACAATATGCAGATATTATTCTGAGGCCAAGGATATGGATGATAACATGACAATGGTCATTGCGTCAGTACAAGAACAACTCAGAAAAGCAAACTTTGAAGACTTCACCGCTATGAAAGAGGCTTGCCAGTATGAGGATATACAGGGtTGTGGTCATCTACCAACCAAAGACATCCATAACCTATGTATGAGATTCAAGGTACCAGCTAAACAACAATTACTTGACACAGTATTAGCAGGAACGAGTACAAACCAACAAGGATTGACCAGTTATAACGAATTCCTAACGTTAATCAACTGGAGAGACTCGCCAGTGAGTCTTCAAAAGTTCGTCCCAGTACAGGCCCCAGAAGCTAAACCATCGGAACGAGTTGGTCCAAAGCAAAGAGTTCGACTCATAAACTACAAGAACCTTCTACAACAACTGCTTTCAaccgaataa

Transcript

ENSDLIT00000006730

TGCTACAAGAACGCCAGTATATCTGACAGTCCCCCCATAAATGTCTCCTCTCCATAAAACCTCTACTCGAGCTTTAACATTGATATTTTGGAACAAAACCATCTCACCAATTCCAAAATGGAAGTTTTTCCACTGCGAGCATTGTAGCGTAGCCTCGTTTTGATGTTTGTTGCTACGATAAACACGCTCCCTTAGTAACCGATTGTCTAACACCAAAGCAGTGCGAGTAAACATTCATTTCTGCATCAAACTAGAATCATGGCGCTTCCTTTCTTACCGGGACAAGTTTTCGACCGAAAACTTGGTAAAACTAAATTTCACAAAACTCATCAGTTTGACTATCGTAATGATGTGTCTTCTTATGTTGGAGAGGCAAAATGTGGAATAGGCGGCGACCCCTTGCCAGGGCAAAAGCTGAGTCCCAAACACAGTGTATTTCCAAAAGGAGTAGGACCAGAAGCACCTTCGTGGGTCGCTTTTGACAGACAAGTTTTATGCTTTGACGCATACTTTCAAGAAGCTGTGCATGAGAAAAGAGAAGAGCAGTATAGGATTAGAAGatgtaaaatatatttctaccTAGAAGATGACAGCATACAAGTTATTGAACCAAAAGTCGAAAATAGTGGAATACCACAAGGAACTCTACTTCGACGTCATCGCATACCTCTTCCTCCTCCTTACGATGAACAGTTTTACACAGTGGAACATTTCAATGTTGGCAaagaaatttcattttattccaAAGTCTTCAAGATTACAGGCTGTGATGAATTCACGCATAACTTCCTCAGAAAACTTGGTGTTAGAGTTAACAACTCATCTAATATCCCAACCGACCCTTATTCTGATCATCGACAAAagTTGGTTGAGAGCATGCAACCTTTGAGACCATATGAAAAGCAAGATACTTTGAAACAGTTCCTACAATATGACCGTCAAGTATTACGTTTCTACTGTCTGTGGGATGATACTGATAGTATGTTTGGTGATGCAAGAGAGATGATACTACACTACTTCCTTGCTGATGATACAGTGGAGATACGTGAAGTGATTCCTGCTAACTCAGGCCGTGATGCTGCACCAATGTTTTTACGCAGACAAAAACTACCTAAGGAACCGGCACAGCTTCGACAGCCTGGAGAGATTACTGGTCGTACTGTATTAAATGTGTTTGGCCCTATGGGTCATGGTGGACGATGGATTCTTGACAGTTTGAAGACTGGTGCAGTGCACACAGACTACTATCTCGACAGTGATCTGACTATTGGATCTTTCATCAATGTTTGGGGAAGAAAGTTCCAGATTTGTGACTGTGATGATTTCACTAAAGACTTTTACAAAACCAAATATGGATTAGATGTGTTTGATTCCATCAAGTACAAGGCTCCACCAGGTGTATTCCCACCTCGTGAAATTCCACCATACAATGGATTTGGTTCAGAGGAAGATTCACTCTGTAACTGCCTCAGTCTTATTCCTAAACCACCTAAGAGAGACTTTAtcaaatttatggaaaaagACAGGGATGGACTTGAGAGTAATGTTCTTCGATTCATGGGTCGTCTCAACACAACTCGCCCTATTGATATGGACAGAAGGTTTATCATTTCCTACTTCCTATCTGATGACACTATCCTGGTCTATGAACCTCAGCAAAGAAATTCAGGAATCCTTGGTGGCAAGTTCTTGGAGAGAAGAAGAATCAAGAGAGACAACCGAGATAATTACTTTTCTGCTCAGGATCTATTCATTGGAGCCCATGTAAATTTCTATAACCATGAGTTTGTCCTGATCGATGCTGATGAATATGCTGTTGACTACATGGAGAATCATCAAGATGAGTTCGTACAAGCCAATATGAGATACATTCTTCCCAAACTAAAGGGAATTGCTGATAATTACTATGAAGAGCTTAAGGCTGTATTCAATGAGCATGATGACAAAGGAACAGGACAGCTAACCTTCAATGCTTTCtggTCCGTCTTAAAGAGGTTTGGTGGCAATCTGACAGAACATGAAATGCTTACAATATGCAGATATTATTCTGAGGCCAAGGATATGGATGATAACATGACAATGGTCATTGCGTCAGTACAAGAACAACTCAGAAAAGCAAACTTTGAAGACTTCACCGCTATGAAAGAGGCTTGCCAGTATGAGGATATACAGGGtTGTGGTCATCTACCAACCAAAGACATCCATAACCTATGTATGAGATTCAAGGTACCAGCTAAACAACAATTACTTGACACAGTATTAGCAGGAACGAGTACAAACCAACAAGGATTGACCAGTTATAACGAATTCCTAACGTTAATCAACTGGAGAGACTCGCCAGTGAGTCTTCAAAAGTTCGTCCCAGTACAGGCCCCAGAAGCTAAACCATCGGAACGAGTTGGTCCAAAGCAAAGAGTTCGACTCATAAACTACAAGAACCTTCTACAACAACTGCTTTCAaccgaataaatgaattatacaATATTAATTATCGCTGATATTGATGGAATTCTTTAACTTTTACTTCTAGATTCAGTAGTTTCCAAGGAAccaacaaacttttttttctggatttGATTTGTATTGTATATAAAAAGTAATTATCCACGATGTATACGAGGCATTTtaagcaaaaattaaaaaagaaaatgatacAGAAATACAATAAAGATATTTTCGTGCTTCATATGGTGTAAAtgctattttttgttaaaCCATGTTTATATATGTTACAGGCAGAgaatttcaatcaattttgggacggac

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q32TG3	EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=2 SV=1
Q32TF8	EF-hand domain-containing family member C2 OS=Danio rerio OX=7955 GN=efhc2 PE=2 SV=2
Q5JST6	EF-hand domain-containing family member C2 OS=Homo sapiens OX=9606 GN=EFHC2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001921 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF06565 all species →	DM10_dom	DM10 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR040193 all species →	Family	EF-hand domain-containing protein EFHC1/EFHC2/EFHB	Interproscan
IPR006602 all species →	Domain	DM10 domain	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12086 all species →	EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0000281 all species →	Biological Process	mitotic cytokinesis	Interproscan
GO:0005874 all species →	Cellular Component	microtubule	Interproscan
GO:0005930 all species →	Cellular Component	axoneme	Interproscan
GO:0007052 all species →	Biological Process	mitotic spindle organization	Interproscan
GO:0010975 all species →	Biological Process	regulation of neuron projection development	Interproscan
GO:0043014 all species →	Molecular Function	alpha-tubulin binding	Interproscan
GO:0060285 all species →	Biological Process	cilium-dependent cell motility	Interproscan
GO:0072686 all species →	Cellular Component	mitotic spindle	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSDLIP00000006272.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →