Detailed information of ENSDLIP00000007387.1 in Diadumene lineata

Genomic Location: chr13:11216579...11245408
NR annotation: XP_031559820.1, myotubularin-related protein 13-like [Actinia tenebrosa]
Species Diadumene lineata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O95248Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4
Q6ZPE2Myotubularin-related protein 5 OS=Mus musculus OX=10090 GN=Sbf1 PE=1 SV=2
Q86WG5Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002736 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00130
all species →
C1_1Phorbol esters/diacylglycerol binding domain (C1 domain)DomainInterproscan
PF00169
all species →
PHPH domainDomainInterproscan
PF12335
all species →
SBF2Myotubularin protein FamilyInterproscan
PF02141
all species →
DENNDENN (AEX-3) domainFamilyInterproscan
PF06602
all species →
Myotub-relatedMyotubularin-like phosphatase domainDomainInterproscan
PF03456
all species →
uDENNuDENN domainDomainInterproscan
PF02893
all species →
GRAMGRAM domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR005112
all species →
DomaindDENN domainInterproscan
IPR043153
all species →
Homologous_superfamilyDENN domain, C-terminal lobeInterproscan
IPR029021
all species →
Homologous_superfamilyProtein-tyrosine phosphatase-likeInterproscan
IPR002219
all species →
DomainProtein kinase C-like, phorbol ester/diacylglycerol-binding domainInterproscan
IPR005113
all species →
DomainuDENN domainInterproscan
IPR001849
all species →
DomainPleckstrin homology domainInterproscan
IPR022096
all species →
DomainSBF1/SBF2 domainInterproscan
IPR001194
all species →
DomaincDENN domainInterproscan
IPR010569
all species →
DomainMyotubularin-like, phosphatase domainInterproscan
IPR011993
all species →
Homologous_superfamilyPH-like domain superfamilyInterproscan
IPR004182
all species →
DomainGRAM domainInterproscan
IPR037516
all species →
DomainTripartite DENN domainInterproscan
IPR030564
all species →
FamilyMyotubularin familyInterproscan
IPR046349
all species →
Homologous_superfamilyC1-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10807
all species →
MYOTUBULARIN-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005085
all species →
Molecular Functionguanyl-nucleotide exchange factor activityInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K18061SBF1_2, MTMR5_13; myotubularin-related protein 5/13-Protein phosphatases and associated proteinsko01009deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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