Genomic Location: chr14:12798678...12822477
NR annotation: XP_020916928.1, ubiquitin carboxyl-terminal hydrolase 48 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families
| CDS |
| ENSDLIT00000008583 |
| Transcript |
| ENSDLIT00000008583 |
| Protein |
| ENSDLIP00000007798.1 |
| UniProt accession | Description |
|---|---|
| Q5ZM45 | Ubiquitin carboxyl-terminal hydrolase 48 OS=Gallus gallus OX=9031 GN=USP48 PE=2 SV=1 |
| A0A0R4IB93 | Ubiquitin carboxyl-terminal hydrolase 48 OS=Danio rerio OX=7955 GN=usp48 PE=3 SV=1 |
| Q86UV5 | Ubiquitin carboxyl-terminal hydrolase 48 OS=Homo sapiens OX=9606 GN=USP48 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003475 (this species only) · gene tree & orthology |
| Ubiquitin family | DUB|USP|USP · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06337 all species → | DUSP | DUSP domain | Domain | Interproscan |
| PF00443 all species → | UCH | Ubiquitin carboxyl-terminal hydrolase | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR035927 all species → | Homologous_superfamily | DUSP-like superfamily | Interproscan |
| IPR006615 all species → | Domain | Peptidase C19, ubiquitin-specific peptidase, DUSP domain | Interproscan |
| IPR018200 all species → | Conserved_site | Ubiquitin specific protease, conserved site | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR028889 all species → | Domain | Ubiquitin specific protease domain | Interproscan |
| IPR050164 all species → | Family | Ubiquitin carboxyl-terminal hydrolases | Interproscan |
| IPR038765 all species → | Homologous_superfamily | Papain-like cysteine peptidase superfamily | Interproscan |
| IPR033841 all species → | Domain | Ubiquitin-specific peptidase 48 | Interproscan |
| IPR044743 all species → | Domain | Ubiquitin-specific-processing protease 48, Ubl domain | Interproscan |
| IPR001394 all species → | Domain | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | Interproscan |
| IPR000626 all species → | Domain | Ubiquitin-like domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24006 all species → | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004843 all species → | Molecular Function | cysteine-type deubiquitinase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0016579 all species → | Biological Process | protein deubiquitination | Interproscan |
| GO:0004197 all species → | Molecular Function | cysteine-type endopeptidase activity | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11858 | USP48; ubiquitin carboxyl-terminal hydrolase 48 | EC:3.4.19.12 | Ubiquitin system | ko04121 | deepkoala |
Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
