Gene detail

Detailed information of ENSDLIP00000008782.1 in Diadumene lineata

Genomic Location: chr12:4420640...4429689
NR annotation: XP_020893850.1, bone morphogenetic protein receptor type-1B isoform X1 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSDLIT00000009749

ACGGCATCTACGTCACATAAACATAAGCTAGTCAAATGGACGACGATTATCTGTGGCGATTTACAGCGAAAATATGTGGCATTTTCAAGCTTTAAATctaattttctttatattgttTAGTATTTTACAAGTTTCAACAGGTTTACTGTGTAAATGCACACAGCATGCATGTCCCGTTGAAGCCAATGAGACATGTACAACAGGTGGCAAGTGTTTCAAAAAGATTGAAGAATTAGATGGCTATGAGCTTATTACCTATGGCTGTCTTTCCCCTGGAGAAAAATCTGATATGCAGTGCAAGACTCCTAGCAAAATATTTAACACAAAGGTGTCGTTGCTCTGCTGTAAGGAGTATGACTTGTGTAATTATGAACTAGAGCCTACATTCCCACCACCCACAATATCTACTTTGGGAGTTCAAGCCAAACAGCAAGAGTCAGTGACCAGTAAACAGTATTTCTATCTGTTTATTACAGCTGGGGCATGTTCATTTGTGTTTGCGGTCTTTCTTGTTGTTCTCTACATGAGGTTCCGAGAGATGAGACGTCGATTGCCTACTCATTTCTCATATGAACGTCACAGCACATTTGTTAGTTCTGGTGAAACACTGAAGGATTACTTTGATCAGAGTTCGGGAAGTGGTTCCGGGCTGCCATTactgGTGCAAAGAACAATTGCCAAACAAGTTACACTTATTCAAAGTGTTGGGAAAGGTCGCTATGGTGAGGTGTGGAAAGCAAGATGGCATGGCGAGGATGTTGCCGTCAAAATATTCCTGTCTCACTGCGAGACTTCTTGGATGAGAGAAACTGAAATTTATCAAACAGTACTACTGCGACATGATAGCATTTTGGGCTTTGTTGCCTCTGACATTATTGGCAGTGGACAAGTAACAAAGTTATACCTTATCACAGACTATCACAGTTTAGGATCCCTGTACGATTTCCTACGGGTTCACAAACTTGACAAGAAGGTCATGTGcaaattggtattttctgctGCAGCTGGTATAGCGCACCTGCATGCAGAGATCCGAGGAACACAAGGAAAACCTATGATAGCCCACAGAGAcattaaaagtaaaaacattCTTGTCAAAGACAATTTAACATGCTGTATAGCAGACTTTGGTCTTGCAGTGAAATATCTACCAGAAAGCAAAGCAATTGATGTGAAGTCTGACAATAGAGTTGGCACCAAGAGGTACATGAGCCCTGAGGTACTCTCACATACACTGGACACAAAGAGCTTTGATGCTTACAGAATGGCCGACATGTATTCATTTGGTCTGGTCTTGTGGGAGATTGCAAGACGTTGCATTActgatgAAACAGGACTTTGTGAAGACTATGAAGTTCCCTACTATGATAATGTTCCACATGATCCCAGTTTTGATGATATGAAGAAAGTAGTAGTGATGGATAGAACAAGACCAGATATTCCAAACAGATGGCACAGAGATGAGacacTAAGAGTCATGGGTAGACTGATGTCTGAGTGTTGGTCTCATCATCCATCAGCAAGAGTTACAGCTCTAAGAGTGAAGAAATCACTGGACAAAATTGTAACAATGAACATGGACACTCCAAATGCCTAATGGTAATCATGGTAATATTGATCTCAAAGTCATGCCACCCATGCATACAAAGTGCGTCTTCTGCTTATttgcaatgagaaaataaaacactaaAGGTTGTATCTATTGCCATACATGCATTTCAGCAACTTAGTGAAGTGTGAAGTCAAGGCATGGCAAGATGATATTGATCAATCATGATaacaaattgaacaaatgCATCATCAGCAATGCCTGTTGGGTTGCTGTGCTGCCCTTTACACACGGATTGTCACTATTACTGGAATACCTAATATGAAACCACTGAAAATCAGGACAATTTTTGCCAAGTGTTTCATGAGGTTTTAATGGGTTTTACTTATGAAAtgcatattattatatatacactcttttgcaagaacgttgtggtatacatttatacaaatatctaatttattcagtacatttaatgatatgcaaagcAATAAACttgctttgtttattgtttgtttcattcgacaaatgtcaaaatatagtTTTCCTATCTATTACAACCTACAAATTATAAACATTTGGTTTCATGTGtaaaaaaatgcttattttCCATTTGGCTTCTcgttagatatttgtataaatgtatactacaatgTTCTTGCAAATGAGggatataaatatatattttcgtGGGTTTTTCAGAGTTTTCATAGCATTCACATGTACcttatgaaattattttaaataacattCTTTCTTGGCTAATAACTATGAAAAACGCATGGAAAAAAAGCATTTCCAGGTTCAAACCCATAAAGACCTATGAAACAGTGTCCCAGTTTTCATTGTGTTTTCATAAGTACTGCAGTGTCTTAATTTGGGCCGATTATTATCCATTTGTTTTGAATCCTGTCTCTTTTTTATCCACAATGAATTATCAGTGGTGGTATTAGAGAGAAATTCAGTATTTGTCATTTCAATAATGAAATAAGAGAGAGAATCTGATGTAAGGGATCAACAGATATGGCACAAATAGACAACCACTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q05438	Bone morphogenetic protein receptor type-1B OS=Gallus gallus OX=9031 GN=BMPR1B PE=1 SV=1
O00238	Bone morphogenetic protein receptor type-1B OS=Homo sapiens OX=9606 GN=BMPR1B PE=1 SV=1
P36898	Bone morphogenetic protein receptor type-1B OS=Mus musculus OX=10090 GN=Bmpr1b PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000505 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01064 all species →	Activin_recp	Activin types I and II receptor domain	Domain	Interproscan
PF08515 all species →	TGF_beta_GS	Transforming growth factor beta type I GS-motif	Family	Interproscan
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR000333 all species →	Family	Ser/Thr protein kinase, TGFB receptor	Interproscan
IPR003605 all species →	Domain	GS domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR045860 all species →	Homologous_superfamily	Snake toxin-like superfamily	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR000472 all species →	Domain	Activin types I and II receptor domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23255 all species →	TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0004675 all species →	Molecular Function	transmembrane receptor protein serine/threonine kinase activity	Interproscan
GO:0005025 all species →	Molecular Function	transforming growth factor beta receptor activity, type I	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007178 all species →	Biological Process	cell surface receptor protein serine/threonine kinase signaling pathway	Interproscan
GO:0009953 all species →	Biological Process	dorsal/ventral pattern formation	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0030509 all species →	Biological Process	BMP signaling pathway	Interproscan
GO:0043235 all species →	Cellular Component	receptor complex	Interproscan
GO:0046332 all species →	Molecular Function	SMAD binding	Interproscan
GO:0071363 all species →	Biological Process	cellular response to growth factor stimulus	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K13578	BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B	EC:2.7.11.30	CD molecules	ko04090	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →