Genomic Location: chr11:186825...199713
NR annotation: AAK27303.1, peptidylglycine alpha-hydroxylating monooxygenase [Calliactis parasitica]
Species Diadumene lineata · all data for this species · gene families
| CDS |
| ENSDLIT00000011761 |
| Transcript |
| ENSDLIT00000011761 |
| Protein |
| ENSDLIP00000010582.1 |
| UniProt accession | Description |
|---|---|
| P12890 | Peptidyl-glycine alpha-amidating monooxygenase B OS=Xenopus laevis OX=8355 GN=pam-b PE=2 SV=1 |
| P08478 | Peptidyl-glycine alpha-amidating monooxygenase A OS=Xenopus laevis OX=8355 GN=pam-a PE=1 SV=3 |
| O01404 | Peptidylglycine alpha-hydroxylating monooxygenase OS=Drosophila melanogaster OX=7227 GN=Phm PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001140 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01082 all species → | Cu2_monooxygen | Copper type II ascorbate-dependent monooxygenase, N-terminal domain | Domain | Interproscan |
| PF03712 all species → | Cu2_monoox_C | Copper type II ascorbate-dependent monooxygenase, C-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036939 all species → | Homologous_superfamily | Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily | Interproscan |
| IPR008977 all species → | Homologous_superfamily | PHM/PNGase F domain superfamily | Interproscan |
| IPR000323 all species → | Domain | Copper type II, ascorbate-dependent monooxygenase, N-terminal | Interproscan |
| IPR020611 all species → | Conserved_site | Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site | Interproscan |
| IPR024548 all species → | Domain | Copper type II ascorbate-dependent monooxygenase, C-terminal | Interproscan |
| IPR000720 all species → | Family | Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase | Interproscan |
| IPR014784 all species → | Homologous_superfamily | Copper type II, ascorbate-dependent monooxygenase-like, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10680 all species → | PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004497 all species → | Molecular Function | monooxygenase activity | Interproscan |
| GO:0005507 all species → | Molecular Function | copper ion binding | Interproscan |
| GO:0016715 all species → | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | Interproscan |
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0006518 all species → | Biological Process | peptide metabolic process | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0005576 all species → | Cellular Component | extracellular region | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00504 | PHM; peptidylglycine monooxygenase | EC:1.14.17.3 | Enzymes with EC numbers | - | deepkoala |
Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
