Gene detail

Detailed information of ENSDLIP00000014683.1 in Diadumene lineata

Genomic Location: not available for this species
NR annotation: XP_020914146.1, sestrin-1 [Exaiptasia diaphana]
Species abbreviation DLINE · all data for this species · gene families

Sequence

CDS

Transcript

ENSDLIT00000016144

ACCAACACTATTACATAGACACAAAGGTTAAAAGGCATCTATTATATACAGAGAAAGCTGTCGAACAATGATTGGGAGAGTTGGTTTCAATATGTCTTCTGACAGGAAAAGgTTTCCTCCCattgatactgatgatgaacAAACTCACTCTCTGTTAGTTGAAGCATTTCTATCTACTGGGCGTGTGTCCAGTGTAACGGCAGTACTGTCAATCCACCCACAGTatttagagttgttttcaagAACAGAGTTCCACATCATGCAAGGGGAAGGCCCATTGCCGTTTGACTGGAGACATTATATCGCAATCATGGCTGCAAGTCGGCACCAGTGTTGTTATCTTGTACATATGTATGAGATGGAGTTTTTAAGATATAATGGTAACAAAGAATGGTTAAAAGGAATTAAACACATACCAAGAAAACTACAGAAACTATCGGATATCAACAAGTATTTAGCTCATCAGCCTTGGCTTATTGAACCAAAACATATCGAGGCATTGCTGAAAGGACAAGACAACTGGTCATTATCAGAACTGATTCAAGCCATCGTTATACTGGCTCATTTTCATTCACTATCAAGTTTATTATTTGGCTGCGGTGTAGTTGAAGAAATAGACCATATTTCAGGACACACATTAAGACCTCCGTCATTAACTGATACTAGTAATGTTAGTATGGACAATCATAACTCTGGAAATAGTGATGTTATTGCAGCAAATGACTTTATGACAGGAGAAGAGCTACTTGAGAGAATGAAACAGGTTTTGGCTGAACAGGACATGATTATGGAAGCCTCACAAGAGGagttatttcaacattttgaaAAGCTTGAAAGTGGAGAACTGGCACAATCTACAAATGATTCAGCCAAGAATGCTCAGAAGCCACAAGACTGTTTAGCGTCAGATGTTGAACACTACTTAGATGACTCCAAATTCCATTACAAGGACTTTGCAAGCCGAGAACACACTGAAATATCAACGTTTCGTATCGGTGATTGTTCTTGGGAGGAGCATGGGTATTCGTTAGTTAATCGACTTTATCCTGATATTGGGACAGTTTTGGATGACAAGTTTAATGTCACTCTTGGTCTAACCTATTTGACTCTTGGTGACAAGACCAATGTTGATACCACTCTATTTCGACGAGCAACATGGAATTATATCCATCTTATATTTGGTATTTACCATGACGACTACCTGTACACTGAGGTCAATAAATTGTTGGAAAGATCATATAAAAGATATATTAAAATGgcAGCAACATGTCCTGAGAAAGTGACTCAACAATGTTACATGGAGTTTATGCCTCAACTAACACATTCTGAAAAGGTTCACGTCAACCTTCTGTTACTAGAAGCAAGACTACAAGCTGAGTTACTTTACGCAGTCCGAGCCATCCTCAAGtatctaaaataaatatatagtcACTTGctaatcatattattattattagaaacGTTGAGAGATTTTTTggtgaaattgtaaaaatgaCAACCACAAATGGAAACAGTGAAAAGAAATTCTATATCAAAAGACAGCAGCAAATCACTTCACTGGAattcttttgtatttgtcCTTCTTTTCCAGTTTTCCATGTCTATTTCATGTGGTTGTTGTGCCTTGGCCATGATAATGTTTAGTACATGAGTCATGGTGACTAAAGGTCAAATGGTTtttgaactgagaaacattgaattcaaaataaagaaaagtgaaaaatgaaGAAGGTGGTTATCAAGGCATCTTAGCTGGCTAGACACTTTTAAGCTATCACGACTCATagttttactattttttcacggtcatatgacAATCACTCTATTAAACATTATCCAGGCTGAGGTTCAATCTTCATTTTTCAACCATAAAATGATCTCTAAGGACTGGAGCTCTATTGCAGTGTTGTCATGGCAACTATAATACATAACTGCCGTAGTAACAAACTGTATCAATGAGGCACATGAAGTGTTCAAATATTAGTCTAAAATGATGTTGGTTACATTTGGTTGcactaaatttattttgttcaaaaatttagtttttttgcaaaaagttttttatataatttgtcttttttgttttgatatgcaAAGCATAAAATTAATATGTATATAGGAGCAGGTATTGTTTTTAcaagtttatttgttattattgataCAGCAACCAATAGTGTCTACATTTCTTTGAGTCATGTAGTCTAGCCAGTGCTAGAAATTAAACCATGTCTGttgattgatcaatttttcCTAAAAATCATACTATTTCTTTTGGTATGAACCCAGGTGTTAGTGATGTTTACATGTTGTGATTgactgggtgtgtgtagtct

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P58003	Sestrin-1 OS=Xenopus laevis OX=8355 GN=sesn1 PE=2 SV=1
Q4R6P7	Sestrin-1 OS=Macaca fascicularis OX=9541 GN=SESN1 PE=2 SV=1
Q9Y6P5	Sestrin-1 OS=Homo sapiens OX=9606 GN=SESN1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006469 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF04636 all species →	PA26	PA26 p53-induced protein (sestrin)	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029032 all species →	Homologous_superfamily	AhpD-like	Interproscan
IPR006730 all species →	Family	Sestrin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12474 all species →	P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:1901031 all species →	Biological Process	regulation of response to reactive oxygen species	Interproscan
GO:0016239 all species →	Biological Process	positive regulation of macroautophagy	Interproscan
GO:0016684 all species →	Molecular Function	oxidoreductase activity, acting on peroxide as acceptor	Interproscan
GO:0070728 all species →	Molecular Function	L-leucine binding	Interproscan
GO:0071233 all species →	Biological Process	cellular response to L-leucine	Interproscan
GO:1904262 all species →	Biological Process	negative regulation of TORC1 signaling	Interproscan
GO:1990253 all species →	Biological Process	cellular response to leucine starvation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10141	SESN1_3; sestrin 1/3	-	Longevity regulating pathway	ko04211	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.