Gene detail

Detailed information of ENSDLIP00000018750.1 in Diadumene lineata

Genomic Location: chr2:28393323...28406194
NR annotation: XP_028516142.1, protein inturned isoform X2 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSDLIT00000020611

ATGCGTCAAGACAACAGCGTCGTTTTTCACCGCAGCACCGTTTCAAGATGGCCGCAACCCAGAAGACGGACATCACACTGCAAAAGACTGAAACTTCTGCAAATACTTCGCACCCGttATGAAGAGCCTCCATGGGTAGGACAAGTGAACGAGAAAGGAGACCTGTTCTATATTGAACCACTAAGAGAACCGTCCCCACCACCAATAAATGGCATTGACAACTTACAGATTAGTGGAAACGCAGGAAAAGACAAGCAAGCCAAAGacaaagatgttttcaaaaagctGAACAATGTCAAGAAAATTTTACCTAATTTAAAACGGGATAAAAacaatgagaaaaaaacagaTGAGAAAAACGTGAAGAATAATCTTGTAGTTGATGGACATGACATGTCTAAGAaacattaccaccaccatgaTAATCATAGCTCAAGTAGAACTTCATTAAAGAAAGATATACATTTAATAGTTTCACCACCAAAGCTTGGGTCTGGACGACATCAAGATCTGGAAACATTGCTTGGTATCATTCCTGGCCGTGATAAGACAGGACGGCTTTCTCAGAATGATAGCTACTCTGGGTCAAGGATTTACATTAAGGGGTTTGTGCCTGATGGACCAGCATTAAAATGTGGAGAACTTAAGATAGGAGACATTATTCTATCATTAAATAAGCTAGATCTCAACTCCAGCAATGTGCATACAATATTGGCAGCTATTACAGGCCCTATGGAGATCATCCTGACAATTCAAAGAACACAGCATCCACCTAAACCAGTGGTGTTGCCAGCTCCTGTCAATAAAGATGATAGTCATTTGATTAAACTGATCAGTGGTCCACCCAGTGGCAGTAGCAATACAAGAACTGATCTTAGAGATCAACCACATGCTGTATTTTATCTTAGCATGACAAGCAGTGAAGATGATGAACCCAACAAGGATATTCTCTACCAGAATCCTGCATCAGATGAAGCCACACAGTTACTAGCATTGAGGGGTGTATTTCTGACATTGAGTGATTTATTAGTGTCAGTCACCGGTACAACTCCGCAAAGCTCCACAGTTATGGTAAAGAAGGAACTGGTGAATGTTGGCTATCACAAGACTGGCAAGCAGCAAGTGATGATTATATGTCTTCCATCAGATAAGGTGTCACTGGTACAGCTTCACCAACTAGTGTCTGATATAACCAAGgtacttcaagtggtattTGGTACAGTTGACAGAGCATTTTGTGGAAGAGGTAACAGACAAAGACTAGATCATTTCTTCTCACTTTTATTTGAGAGCATATTAGGACGTTCTTCTGGCTCATCAAGTAAAGGAAAGACAACTCTTAGTAATTATAGTTTTTTGGAATGCTTACCTGGAGTTCAGTGTCTAAATCTTCCAACTACGTCAATGGTGAATATCAACTGCTGCTTGAGTGACTTGGAGGCTGCTGATTATGGTGAACTTGTAGatgaattatttcaaattagaAGATTATACACAATTTTAGGATCATGCATATTTTATAAGgGTATGCTGTTGGCAAATCATTTAATTTCAGAGGATTTTCaagatattttattatattgtaaatattattgtttgttggatgttggacaaaaacaaaaaataggaCAACTTGTTGTATGGAAAGAGATATTTTTAACCAGACGGCATAACAAAAGAGACAACAGAACAGAATATAGGGAACCATCTGGTAGACATTTTGTGCTGATTGTTGGACAGAAGCATATGCTGCTTTGTGTAGTGCTTGAGGCTGGAGGAGTAGCGAGAAAGGCTGAAGGCTTTCCAGGACCAGATTCCTACTATGTGGAACAGCTGAAAAATACATTGATGCAGATAGAAACAATGGATATATCATCAGTTTGTGAAGCAAGTCTTCGCAGTGCACCAAACCCACCAATCATTTCTGCTGACCTTGTTTTGTCAAATTCTGCAACTGTCTCCACAAGTGAACGCAACAGCTCTTTCAACCTTGCAAATCCAGCTACCCCACCACAAGGCAGAAGATATGGTAGCCTTGATAGCTTGAAACTACCTGGTGATGAGCTTGATTCATCTGACAGTGGTAGTCTGCCATTCAAACGGAGAGGTTCTGATAGCTCTGGTAGCCAAAACAGTCTCTCAGCTAAAGGCAAACTAAGATCGTACAGATCATTATCTTCTTTAACTTGTGTGGGAACTTTGAGAAAGAGTTTTACTGAAAGTCCTTTTGACTTAGCACAGTCTAACAACTCCAGATTGACATTCGGTAAAGAGAATACCCTGTTCAACTATGTAACTTTTGATTCATTCAGTGGAGTTCTAATGTGTCCTACCTCTACGGACAATGTGTCAAGATCTGGAAGTGTTCATACTGAAGTCATGCAGAATTTTTACAACACTTGTCTTACTATTCGAAAATATTTTCTTCCATATTATAAACAGAGGTTAAAATCAACAAGTAGCAAAAGTAGAGATAAGTCCAATTTTTCAAATCCATATCAAGAAACCACACTCGAACGTGGTGTATTATTTCATCGTATGCCAGACACTACAGAACAGAAAAAGACTGCACCCACATTGAAATATTGGGTAATTGGccGACTGTTTCCAGATGAACATCCCAGAGAGTTCTACGTTTGTTATCACAGTAAAATACCTCAGAACATGGTAGAAATGGCATTTAAACTGGGATTTGGAGTAGCAATATGA

Transcript

ENSDLIT00000020611

TTACGCCCGAGGGAAGGAAAAGGGCAGACTGCATAGACTTCTGCCAGTAAGCAATGACTACAGCTGTCATGACTAATTACTAGAACCACAGTAGCATACAAAGGACGGTGTATCGTCAAACATAACAGTTAGAGTTTtaaagtgacaaaaaaaacCGTCAAAGACGCAGAGATAGCTCGGACAAATGCGTCAAGACAACAGCGTCGTTTTTCACCGCAGCACCGTTTCAAGATGGCCGCAACCCAGAAGACGGACATCACACTGCAAAAGACTGAAACTTCTGCAAATACTTCGCACCCGttATGAAGAGCCTCCATGGGTAGGACAAGTGAACGAGAAAGGAGACCTGTTCTATATTGAACCACTAAGAGAACCGTCCCCACCACCAATAAATGGCATTGACAACTTACAGATTAGTGGAAACGCAGGAAAAGACAAGCAAGCCAAAGacaaagatgttttcaaaaagctGAACAATGTCAAGAAAATTTTACCTAATTTAAAACGGGATAAAAacaatgagaaaaaaacagaTGAGAAAAACGTGAAGAATAATCTTGTAGTTGATGGACATGACATGTCTAAGAaacattaccaccaccatgaTAATCATAGCTCAAGTAGAACTTCATTAAAGAAAGATATACATTTAATAGTTTCACCACCAAAGCTTGGGTCTGGACGACATCAAGATCTGGAAACATTGCTTGGTATCATTCCTGGCCGTGATAAGACAGGACGGCTTTCTCAGAATGATAGCTACTCTGGGTCAAGGATTTACATTAAGGGGTTTGTGCCTGATGGACCAGCATTAAAATGTGGAGAACTTAAGATAGGAGACATTATTCTATCATTAAATAAGCTAGATCTCAACTCCAGCAATGTGCATACAATATTGGCAGCTATTACAGGCCCTATGGAGATCATCCTGACAATTCAAAGAACACAGCATCCACCTAAACCAGTGGTGTTGCCAGCTCCTGTCAATAAAGATGATAGTCATTTGATTAAACTGATCAGTGGTCCACCCAGTGGCAGTAGCAATACAAGAACTGATCTTAGAGATCAACCACATGCTGTATTTTATCTTAGCATGACAAGCAGTGAAGATGATGAACCCAACAAGGATATTCTCTACCAGAATCCTGCATCAGATGAAGCCACACAGTTACTAGCATTGAGGGGTGTATTTCTGACATTGAGTGATTTATTAGTGTCAGTCACCGGTACAACTCCGCAAAGCTCCACAGTTATGGTAAAGAAGGAACTGGTGAATGTTGGCTATCACAAGACTGGCAAGCAGCAAGTGATGATTATATGTCTTCCATCAGATAAGGTGTCACTGGTACAGCTTCACCAACTAGTGTCTGATATAACCAAGgtacttcaagtggtattTGGTACAGTTGACAGAGCATTTTGTGGAAGAGGTAACAGACAAAGACTAGATCATTTCTTCTCACTTTTATTTGAGAGCATATTAGGACGTTCTTCTGGCTCATCAAGTAAAGGAAAGACAACTCTTAGTAATTATAGTTTTTTGGAATGCTTACCTGGAGTTCAGTGTCTAAATCTTCCAACTACGTCAATGGTGAATATCAACTGCTGCTTGAGTGACTTGGAGGCTGCTGATTATGGTGAACTTGTAGatgaattatttcaaattagaAGATTATACACAATTTTAGGATCATGCATATTTTATAAGgGTATGCTGTTGGCAAATCATTTAATTTCAGAGGATTTTCaagatattttattatattgtaaatattattgtttgttggatgttggacaaaaacaaaaaataggaCAACTTGTTGTATGGAAAGAGATATTTTTAACCAGACGGCATAACAAAAGAGACAACAGAACAGAATATAGGGAACCATCTGGTAGACATTTTGTGCTGATTGTTGGACAGAAGCATATGCTGCTTTGTGTAGTGCTTGAGGCTGGAGGAGTAGCGAGAAAGGCTGAAGGCTTTCCAGGACCAGATTCCTACTATGTGGAACAGCTGAAAAATACATTGATGCAGATAGAAACAATGGATATATCATCAGTTTGTGAAGCAAGTCTTCGCAGTGCACCAAACCCACCAATCATTTCTGCTGACCTTGTTTTGTCAAATTCTGCAACTGTCTCCACAAGTGAACGCAACAGCTCTTTCAACCTTGCAAATCCAGCTACCCCACCACAAGGCAGAAGATATGGTAGCCTTGATAGCTTGAAACTACCTGGTGATGAGCTTGATTCATCTGACAGTGGTAGTCTGCCATTCAAACGGAGAGGTTCTGATAGCTCTGGTAGCCAAAACAGTCTCTCAGCTAAAGGCAAACTAAGATCGTACAGATCATTATCTTCTTTAACTTGTGTGGGAACTTTGAGAAAGAGTTTTACTGAAAGTCCTTTTGACTTAGCACAGTCTAACAACTCCAGATTGACATTCGGTAAAGAGAATACCCTGTTCAACTATGTAACTTTTGATTCATTCAGTGGAGTTCTAATGTGTCCTACCTCTACGGACAATGTGTCAAGATCTGGAAGTGTTCATACTGAAGTCATGCAGAATTTTTACAACACTTGTCTTACTATTCGAAAATATTTTCTTCCATATTATAAACAGAGGTTAAAATCAACAAGTAGCAAAAGTAGAGATAAGTCCAATTTTTCAAATCCATATCAAGAAACCACACTCGAACGTGGTGTATTATTTCATCGTATGCCAGACACTACAGAACAGAAAAAGACTGCACCCACATTGAAATATTGGGTAATTGGccGACTGTTTCCAGATGAACATCCCAGAGAGTTCTACGTTTGTTATCACAGTAAAATACCTCAGAACATGGTAGAAATGGCATTTAAACTGGGATTTGGAGTAGCAATATGAGAATTCTCTTAGTTGTCAACCAAATTAGAGCAAGATACCCAAAACTATGACCATCCAGTGATCAGtatttttcatacttttaaGCCTACATTTCAGTCATCATTTGCACTGCAATCTAAACATTGTGCTAATGCAAAGTAGACATCTATAGCAGTTAGCTTATTGACTGGTCATATTTTTCAGCTTCAAGCTGTAAATCATATATAGGTTTTGTGAAAGTTAATGAGGTGGACATTGATAGCAAAATAGTAAAATggtgaaatcaataaaaatgggAAACTATACTATGGTGTAAAGGTTGTTACACACGACGGCAAGTCGTAGTGACTTTTCCCTGAGACAGGTCGCAGTGACAATTTTTCCCAGTGTGTACTAAGCATTTTGATGGAGATTGTAGTCGCtgtgacagaattttgtcgctgtgATTTgccaaatgaaatcaaatctcCCTCAGGCCAAAGAGATGTCTAGGCAATGAATGTTGAACCAGTGTACACTGAGGTGACCTGTTGCAGGGACATGTCACAGCAACTTGTCAAGTAGTGTGTACCAACCTTAAAGCTAGAAGTCAACTCCATATGTGCAATTATCGTCAAAAAGCTATTTAGTCATTCATGCTTATCCATAATGACATATTTTCCTTTACAATGCCTAgtataattacaaaacaatcaatatcatcactaAAATTATgtacataaaaatataaatcacagacaatattttgttattcatcTATAAAGATGTTATAGTAGTTCTAATGCAATTGCTCCACAATAAAACACAAGAAATATA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
F1MDL2	Protein inturned OS=Bos taurus OX=9913 GN=INTU PE=3 SV=2
E7FCN8	Protein inturned OS=Danio rerio OX=7955 GN=intu PE=3 SV=1
Q2I0E5	Protein inturned OS=Xenopus laevis OX=8355 GN=intu PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002132 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF19033 all species →	Intu_longin_3	Intu longin-like domain 3	Domain	Interproscan
PF19031 all species →	Intu_longin_1	First Longin domain of INTU, CCZ1 and HPS4	Domain	Interproscan
PF00595 all species →	PDZ	PDZ domain	Domain	Interproscan
PF19032 all species →	Intu_longin_2	Intu longin-like domain 2	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036034 all species →	Homologous_superfamily	PDZ superfamily	Interproscan
IPR043989 all species →	Domain	CCZ1/INTU/HPS4, third Longin domain	Interproscan
IPR043987 all species →	Domain	CCZ1/INTU/HSP4, first Longin domain	Interproscan
IPR001478 all species →	Domain	PDZ domain	Interproscan
IPR043988 all species →	Domain	CCZ1/INTU, second Longin domain	Interproscan
IPR039151 all species →	Family	Protein inturned	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR21082 all species →	PROTEIN INTURNED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0016192 all species →	Biological Process	vesicle-mediated transport	Interproscan
GO:0001736 all species →	Biological Process	establishment of planar polarity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005929 all species →	Cellular Component	cilium	Interproscan
GO:0007399 all species →	Biological Process	nervous system development	Interproscan
GO:0060271 all species →	Biological Process	cilium assembly	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K22862	INTU, CPLANE4, PDZD6; protein inturned	-	Domain-containing proteins not elsewhere classified	ko04990	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →