Gene detail

Detailed information of ENSDLIP00000018803.1 in Diadumene lineata

Genomic Location: chr3:13772795...13814265
NR annotation: XP_020915465.1, microtubule-associated serine/threonine-protein kinase 2 isoform X1 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSDLIT00000020679

ATGGAGAGCTCAGATAGGACTGACAAGGAGGGAAGCTCGTTTAGTCAAGATAGGCTGGCCTTGCGAGCTTATCTCGAAAAGGAATCTTTACTTCACCTCGATAAAATATTCCCCGATTATATATCGTTGGACTACTTCAAAACTGTGACAGATGACGATCTTGAGCATGACTTCCATATTAAAGACGCGAAGCTTCGGCTTGAAATTATGAAAGCTGTTATAAAATGCAGGGACGATGATAATAATTCGGGCAATGAACACGAGGAGTCTGACTGTGAGCTTGGCCTGCAATTAAGTGCTGGTTCTCAATCTGATGTTTTTGTGTCATCTACTCTACCAAAGGATTTCCGATTCCGGCACAATAGACTTTCTGATGACTTTGGCCGATATAGAGGTGAAAGCATTGGAGGATATCATAGTTCACGGGGTGAAGAAACATCTAACTTAGTTCGCATGAGAGCAAACCCATCGCTTGGTAACTCAGAACCAAACCTGTCTGGAAGTTGTGGAGACCTAAGTAGAAGACTAAGcACCTGTAACATTAATGGACGAGCAAAAACTAAGAGCTTTATAGAAAATACCAGCTCAGCCTTCCAGCCTCCACCTGCTAATAATGGAAACCATTTTATGTTCTCTGGTGTTAGAAAGGCTGATGGTGGTGGTCGTAGATGGTCTGTAGCATCGCTAACTTCATCTGGATATGGAACACATACGCCTTGCTCATCATCATACTCAtcTTTGTCATCTTCACAAGAAAAGATCCAGCAGTGGGGTCAAATGTATCAGGATGAGTTAAACTTCTTAGGTTTAAGTGCTGAAAGTGATCAAGAAGAAGATAGTGGATGGAAATCACCTAAACCAAGGCTGCAGAGATCAAGAAGTCTTAGTCCCACTAGGTCATTCATTGCTCATGAAGATGATTTACAGCTTCTTAATAACTTATACAAAGAACGATTTCCAAAGGCTGTGCAGCAGATGGAAGAAATGCTACAGGAGTTTATTGATGATTACACAAGCGAGACATATGGCAGTATGTTCGGTTGCGATGGAGTGTTAAACTTTGTTTGGCATCAAGTGGTAGAAACAGCAAGGGATGTTCTCAAACAGTCACAGGATAACTCACTGACAAGCAGATATTTCTATGACTTGTCAGAAACCATGGATAGGTTGTTATTTGAgTCCAAACAAAAGACTGATGTTGATCTTACTCCTATCATACGAATCATGAGAAAGTTGCTGATAATAGTGTCAAGGCCTGCTAGACTATTAGAGTGCCTGgAATTCAAGCCAGGAGAGTTCTATAATATGCTGGAAAATGAATCTAGAGAAATGGTATACACTAAAGAAAACTTAGATATCACAAAATATGTCAAAGCACATCTAGGTATTCCTGATGCTAGTGATTTAGACCAAGAACAgcttgataatgatgatacgCCAGCTGCTAAACCTGTTGCCCAACCTGCAGAAGATGATTTTGATTACATCAAACTCATCAGCAATGGAGCTTATGGCGCTGTATATCTTGTTAAGCATAAAACCACCCAGATTAGGTTTGCAATGAAGAAGATCAGTAAACATGTCATGATGCTGAAGAACCAAGTGGAACAAGTATTTGCGGAGAGAGACATCTTAACCTTTGCTGAAAACCCTTTTGTAGTTGGACTTTGGTGCTGTTTTGAAACAAAGAAACATTTATGTATGGTAATGGAATATGTAGAAGGTGGTGATTGTGCTTCATTGTTAAAGAACATCGGTGCTTTGCCAGCGGATCTAGCAAGGATGTACTTTGCTGAAACGGTTCTAGCTGTTGAATATCTTCACAGTTATGGTATTGTTCACAGAGACATCAAACCTGACAATTTACTAATCACTTCACTTGGCCATATCAAGCTGACAGACTTTGGGCTTTCAAAGATAGGATTAATGAACTcAACAACAAGAATGTATGAACATTCACTGGACCACGACGTCCATCAGTTTACTGATCAGCAAGTCTTTGGCACACCAGACTATCTAGCCCCAGAGGTTATTCTACGGCAGGGTTATGGACGGGCTGTAGACTGGTGGTCCATGGGGATTATTCTGTATGAATTCCTTGTTGGTGTGCCTCCATTTTATGGGGAGACCCCTGAGGAACTATTTGCACATACATTGAGTGGTGACATTGAATGGCCAGATGGTGAAGAAGGTTTCCCAGAGGACGCACAGGACTTGATTAAGAAATTGCTTGAGCAGGACCCCACATCCAGACTGGGCACTGTTGGTGCCATAGAGGTAAAGGAGCATTGCTTCTTTGAGGGAGTCAATTGGACAGCTTTGTTAAGACAGAAAGCTGAGTTTATTCCTCAGTTagatggtgaagatgataCCAGCTACTTTGACACTCGCACTGACCGCTACAATCATAGCTTCGAGAcagatgctgatgatgatgatgaagattatGACGACATACCAGACTTCACCAATTTCTCAACCTGTTCTCCACGATACTCCAGAATTCTAGCTTCTCCAGTTCCCTCAACTCCTGATTCACCAAGTCCAAAGGGAACCCAAAAGTTCAACAAAAGTGAATCACCAACGTTAAACCGTAAACGTTCAGACAGCTCACCACCAATGGTTCGACGGCACCGTCCGCAAGAAGAGCTGGACCTTAAAATTGATGAGTCGCCGTTACCAAGGCTACGGCCTCGTAGTGAGAGTGGCTCAGATGTTGAATCAACAAGGCAGACTATATCGCCATTGATCTTTGAttcTCCTCCAGGTCATACAAGCTCACCAGACTCCCCACCCACCCCTCCCACTGTAAGACTACGTAAAAAAGGTTCAAATTCGCGATTCACACCGCTGCTGACCACCATGTCCATGGATGGTGTAGGCACAGACTCGCGTCATGATATCTCGCCAAAAGAACACAAACCTGTGGATCTACGCGTAGCCTTACATCGTACCCAGTCTCTCCCACCACGGTCAAGACCGTCAGTACCGAAATTGGAACTGCCAAGCTGCGATATCAGTGGTAAAAATAGCCCACCTGCCTCACCACGATATGACTCGACACCACCAGCGTCTCCTCGTAGACGTCGTACCAGTACGTTATCCATGTGCCTAAGACCACCTATTGTGATAGAGAAGGGGCCACGTGGCTATGGGTTTACTCTACAAGCAATACGAGTGTACTATGGTGACTCCAATTACTTTACTGTTCATCACTTAGTCTCGAGCGTGGACCACGGCAGCTCAGCGTTCGAGGCTGGTCTTCGTCCTGGTGATCTACTAACACATGTCAACGATGAGTCCGTAACGGGGCTGACGCATCGTCAAGTAGTGGAACTAATCCTGGGAGGAGGTAGCCGAGTGAAGCTGAATGCTACAGAGCTATCGAAAACATCCATTAAAACTGGCGGTCGACGACGTTTACCATCTGCCATCAAACGAGTACGAAAAAGAACACGAAGATCAAGAAAGAATACATCATCACCAACCAATCACCGACCTTCTACACCAGAAGTCGAGAAAACACCTACGAAACATCGACCATTCTGGAAGCGGTTTGGTCGACGAAGTAGCCATGCGGGATTAAGAAGAACCAGTTCACTCAAAAAGGTTGGATCTTTCGAAAATAAAGGCAATCGACCTAGTTCGCCGAAATTCGGTTCGCCGTCGTTTGACTTTCGTAATGTGTCCGACAACTCTTCGTCGTCGTCTTTGAGTAGCAGTGGGCCCTCGTCACCAAGCTCCCCAACGGCGTTATCGTTAGGAAGGCCTGGTATGTGGAAGATACGGATTCAGCAAATcattcaaaagatattttctgTGATGAATCggAGGGCAACAGTTTCATGGCAACAAGCCTGGCAACACAAATATGAATTACAAGCCATCATATGA

Transcript

ENSDLIT00000020679

GCAAATAGTATTGGAAAAAGGTATTGCGGTATTTTTCTCGTGAAAAATGCTCTAACACCGCAACAAATCGATGTGGAATTTGAGCTAGGACTTGCTCTTTGTGATGTTGAACGGCAAGAGGGAATAGACGACGAATACGAGACATTTGTTGTTAAATGTGAAGGTGTTCGCCTCGGCTCTGGTGTTTGTTCCAAGCATGTCGACCTGGCTACAAGATAAATCTAGCTCGGTTTTGCTTGAAACTCGATTTCACATGATTTTATTGAAAGCTACGGTGTAAAGAAACGTACTAGTTTAGTATGGAGAGCTCAGATAGGACTGACAAGGAGGGAAGCTCGTTTAGTCAAGATAGGCTGGCCTTGCGAGCTTATCTCGAAAAGGAATCTTTACTTCACCTCGATAAAATATTCCCCGATTATATATCGTTGGACTACTTCAAAACTGTGACAGATGACGATCTTGAGCATGACTTCCATATTAAAGACGCGAAGCTTCGGCTTGAAATTATGAAAGCTGTTATAAAATGCAGGGACGATGATAATAATTCGGGCAATGAACACGAGGAGTCTGACTGTGAGCTTGGCCTGCAATTAAGTGCTGGTTCTCAATCTGATGTTTTTGTGTCATCTACTCTACCAAAGGATTTCCGATTCCGGCACAATAGACTTTCTGATGACTTTGGCCGATATAGAGGTGAAAGCATTGGAGGATATCATAGTTCACGGGGTGAAGAAACATCTAACTTAGTTCGCATGAGAGCAAACCCATCGCTTGGTAACTCAGAACCAAACCTGTCTGGAAGTTGTGGAGACCTAAGTAGAAGACTAAGcACCTGTAACATTAATGGACGAGCAAAAACTAAGAGCTTTATAGAAAATACCAGCTCAGCCTTCCAGCCTCCACCTGCTAATAATGGAAACCATTTTATGTTCTCTGGTGTTAGAAAGGCTGATGGTGGTGGTCGTAGATGGTCTGTAGCATCGCTAACTTCATCTGGATATGGAACACATACGCCTTGCTCATCATCATACTCAtcTTTGTCATCTTCACAAGAAAAGATCCAGCAGTGGGGTCAAATGTATCAGGATGAGTTAAACTTCTTAGGTTTAAGTGCTGAAAGTGATCAAGAAGAAGATAGTGGATGGAAATCACCTAAACCAAGGCTGCAGAGATCAAGAAGTCTTAGTCCCACTAGGTCATTCATTGCTCATGAAGATGATTTACAGCTTCTTAATAACTTATACAAAGAACGATTTCCAAAGGCTGTGCAGCAGATGGAAGAAATGCTACAGGAGTTTATTGATGATTACACAAGCGAGACATATGGCAGTATGTTCGGTTGCGATGGAGTGTTAAACTTTGTTTGGCATCAAGTGGTAGAAACAGCAAGGGATGTTCTCAAACAGTCACAGGATAACTCACTGACAAGCAGATATTTCTATGACTTGTCAGAAACCATGGATAGGTTGTTATTTGAgTCCAAACAAAAGACTGATGTTGATCTTACTCCTATCATACGAATCATGAGAAAGTTGCTGATAATAGTGTCAAGGCCTGCTAGACTATTAGAGTGCCTGgAATTCAAGCCAGGAGAGTTCTATAATATGCTGGAAAATGAATCTAGAGAAATGGTATACACTAAAGAAAACTTAGATATCACAAAATATGTCAAAGCACATCTAGGTATTCCTGATGCTAGTGATTTAGACCAAGAACAgcttgataatgatgatacgCCAGCTGCTAAACCTGTTGCCCAACCTGCAGAAGATGATTTTGATTACATCAAACTCATCAGCAATGGAGCTTATGGCGCTGTATATCTTGTTAAGCATAAAACCACCCAGATTAGGTTTGCAATGAAGAAGATCAGTAAACATGTCATGATGCTGAAGAACCAAGTGGAACAAGTATTTGCGGAGAGAGACATCTTAACCTTTGCTGAAAACCCTTTTGTAGTTGGACTTTGGTGCTGTTTTGAAACAAAGAAACATTTATGTATGGTAATGGAATATGTAGAAGGTGGTGATTGTGCTTCATTGTTAAAGAACATCGGTGCTTTGCCAGCGGATCTAGCAAGGATGTACTTTGCTGAAACGGTTCTAGCTGTTGAATATCTTCACAGTTATGGTATTGTTCACAGAGACATCAAACCTGACAATTTACTAATCACTTCACTTGGCCATATCAAGCTGACAGACTTTGGGCTTTCAAAGATAGGATTAATGAACTcAACAACAAGAATGTATGAACATTCACTGGACCACGACGTCCATCAGTTTACTGATCAGCAAGTCTTTGGCACACCAGACTATCTAGCCCCAGAGGTTATTCTACGGCAGGGTTATGGACGGGCTGTAGACTGGTGGTCCATGGGGATTATTCTGTATGAATTCCTTGTTGGTGTGCCTCCATTTTATGGGGAGACCCCTGAGGAACTATTTGCACATACATTGAGTGGTGACATTGAATGGCCAGATGGTGAAGAAGGTTTCCCAGAGGACGCACAGGACTTGATTAAGAAATTGCTTGAGCAGGACCCCACATCCAGACTGGGCACTGTTGGTGCCATAGAGGTAAAGGAGCATTGCTTCTTTGAGGGAGTCAATTGGACAGCTTTGTTAAGACAGAAAGCTGAGTTTATTCCTCAGTTagatggtgaagatgataCCAGCTACTTTGACACTCGCACTGACCGCTACAATCATAGCTTCGAGAcagatgctgatgatgatgatgaagattatGACGACATACCAGACTTCACCAATTTCTCAACCTGTTCTCCACGATACTCCAGAATTCTAGCTTCTCCAGTTCCCTCAACTCCTGATTCACCAAGTCCAAAGGGAACCCAAAAGTTCAACAAAAGTGAATCACCAACGTTAAACCGTAAACGTTCAGACAGCTCACCACCAATGGTTCGACGGCACCGTCCGCAAGAAGAGCTGGACCTTAAAATTGATGAGTCGCCGTTACCAAGGCTACGGCCTCGTAGTGAGAGTGGCTCAGATGTTGAATCAACAAGGCAGACTATATCGCCATTGATCTTTGAttcTCCTCCAGGTCATACAAGCTCACCAGACTCCCCACCCACCCCTCCCACTGTAAGACTACGTAAAAAAGGTTCAAATTCGCGATTCACACCGCTGCTGACCACCATGTCCATGGATGGTGTAGGCACAGACTCGCGTCATGATATCTCGCCAAAAGAACACAAACCTGTGGATCTACGCGTAGCCTTACATCGTACCCAGTCTCTCCCACCACGGTCAAGACCGTCAGTACCGAAATTGGAACTGCCAAGCTGCGATATCAGTGGTAAAAATAGCCCACCTGCCTCACCACGATATGACTCGACACCACCAGCGTCTCCTCGTAGACGTCGTACCAGTACGTTATCCATGTGCCTAAGACCACCTATTGTGATAGAGAAGGGGCCACGTGGCTATGGGTTTACTCTACAAGCAATACGAGTGTACTATGGTGACTCCAATTACTTTACTGTTCATCACTTAGTCTCGAGCGTGGACCACGGCAGCTCAGCGTTCGAGGCTGGTCTTCGTCCTGGTGATCTACTAACACATGTCAACGATGAGTCCGTAACGGGGCTGACGCATCGTCAAGTAGTGGAACTAATCCTGGGAGGAGGTAGCCGAGTGAAGCTGAATGCTACAGAGCTATCGAAAACATCCATTAAAACTGGCGGTCGACGACGTTTACCATCTGCCATCAAACGAGTACGAAAAAGAACACGAAGATCAAGAAAGAATACATCATCACCAACCAATCACCGACCTTCTACACCAGAAGTCGAGAAAACACCTACGAAACATCGACCATTCTGGAAGCGGTTTGGTCGACGAAGTAGCCATGCGGGATTAAGAAGAACCAGTTCACTCAAAAAGGTTGGATCTTTCGAAAATAAAGGCAATCGACCTAGTTCGCCGAAATTCGGTTCGCCGTCGTTTGACTTTCGTAATGTGTCCGACAACTCTTCGTCGTCGTCTTTGAGTAGCAGTGGGCCCTCGTCACCAAGCTCCCCAACGGCGTTATCGTTAGGAAGGCCTGGTATGTGGAAGATACGGATTCAGCAAATcattcaaaagatattttctgTGATGAATCggAGGGCAACAGTTTCATGGCAACAAGCCTGGCAACACAAATATGAATTACAAGCCATCATATGATAGCTGTTCTATTCCCAGCAAAAGACCAAGATTCTAACCAATGTCTGTATACTCTGTCACTAAAACGTATATGGT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q60592	Microtubule-associated serine/threonine-protein kinase 2 OS=Mus musculus OX=10090 GN=Mast2 PE=1 SV=1
Q6P0Q8	Microtubule-associated serine/threonine-protein kinase 2 OS=Homo sapiens OX=9606 GN=MAST2 PE=1 SV=2
Q9R1L5	Microtubule-associated serine/threonine-protein kinase 1 OS=Mus musculus OX=10090 GN=Mast1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002397 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00595 all species →	PDZ	PDZ domain	Domain	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF08926 all species →	DUF1908	Domain of unknown function (DUF1908)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR023142 all species →	Homologous_superfamily	Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR036034 all species →	Homologous_superfamily	PDZ superfamily	Interproscan
IPR001478 all species →	Domain	PDZ domain	Interproscan
IPR037711 all species →	Domain	Microtubule-associated serine/threonine-protein kinase, catalytic domain	Interproscan
IPR050236 all species →	Family	Serine/threonine-protein kinases, AGC	Interproscan
IPR000961 all species →	Domain	AGC-kinase, C-terminal	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR015022 all species →	Domain	Microtubule-associated serine/threonine-protein kinase, pre-PK domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24356 all species →	SERINE/THREONINE-PROTEIN KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0018105 all species →	Biological Process	peptidyl-serine phosphorylation	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0000287 all species →	Molecular Function	magnesium ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08789	MAST, IREH1; MAST-subfamily protein kinase	EC:2.7.11.37	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →