Gene detail

Detailed information of ENSDLIP00000021379.1 in Diadumene lineata

Genomic Location: chr3:9997556...10001632
NR annotation: KXJ11064.1, Dimethylaniline monooxygenase [N-oxide-forming] 5 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSDLIT00000023646

GCACGAACAAACTGTATCAGCTGCAGAATTCGAAAGAGATATTTGGTTAAAGAGTCTTATTCTTCTATCAAAGGTACAAGTATTCTACAATTTGCAGTCCAAACGAGGCTGAAAAATCAACGACACAAAAGAGGAAAAACATTTGAGTTTTTCTAAAAAACAGATTTCGTAGTTGGCAAACTACGAAATTGAACTAGAACTGAAATACAAGAGCATTTCCAtctctgtttttttaaagaagagaaaattaaaacatagCTGTCACGATAAACTGCCGTAGTTTAAAACTGGAAACCAAGAtggaaaacaagcaaaaaactGTCGCTATCATCGGCGCAGGGGCCAGCGGTTTAACATCCATCAAAGCCTGTCTCGAAGAAAACCTTCTTCCAGTCTGCTACGAAAAAGAAAGTTCTCTTGGCGGACTATGGAACTACAACGAAAACTCCAGCCGCACTTCAGTGTACAAATCGGCTGTCATTAACACCAGCCGCGCAATGAGTGGATTTTCTGATTTTCCAATCCCAAAACGATATCCGATATTTATGCCACACGGACAAGTCTTAGAGTACTTGCATCTTTACGCGTCTCGATTTGAACTATATGATTATATTCACTTTAGCACCAGTGTGGTACAGGTTTCTAAAGCAGAGAATTACGAAGTTACTGGCCAATGGATTGTATGTTATCGTTCTGAAGGCTCAGAAGTTAAGTCGAGGGTTGTTGATAGTGTGTTGGTCTGCAGTGGTCATTTGTGGAGTCCGTCATATCCGAGCTTTCATGGCATGAATCTGTTTGAAGGTCTTCAAATGCACAGTCACTCGTACAGGAACCATGAAGATTTCAAAGACAAGAGAGTTTTGGTAGTTGGTCTTGGCAACTCTGCTGCAGACGTCGCCACAGAACTAAGTCACTGCGCTTCACAAGTCTATCTAAGCACCCGCAGAGGCGCATGGGTTATCTCTAGATTGTCCAATCAGGGAGTCCCGTGGGATCATTACTATGAAAGAAGAGTCTATGACAGGCTTCCCAGCAAGATTCTTGAATggatgtttttgaaatgtgcACAAGGAAGATTTGATCACAGTAGTTACGGCCTTCGGCCGAAACACGGAATTCTCAATGCACCTTGTGTCATCAGCGACGAGCTACCACATCGCATCGCCAACGGCTCCCTAAAGCTGACACCAAACATCTCACGTTTTACACAAACCGGCGTCGTCTTCGAAGACGGGAGTGCAGTTGACGACCTCGATGTCGTTATCTTCTGCACTGGCTACAAAATAACGTTTTCGTTTCTTAGCAACGAGGTCATTAAAGTCCAGAATAATCACGTGACTTTATACAAGTATATGTTTCCACCTGATCATGCGCATCCAACAATGGCGTTTATTGGTCTGACCCAGTCCTCCGGAGCCATGTTCTCCTTAATGGAGATTCAGGCACGCTGGGCATCACGGGTAATATCTGGGAAGTGTAGTCTTCCTTCGAAGGACGTAATGTCACGTGATATAAAGAGCAAGAGGGAGGATATGGAGGATAGTTTTATTCGCACAAAGAGATGTACGATTCAGGTTTCAAGCATTGCTTACAAAGACGAAATTGCTGATCTAATCGGCTGCAAGCCTGCACTTTTCAAACTCCTTTTCACGGATCCATTTCTTGCTCTGCTGTGCTTCTTTGGTCCTTGTACGCCTTCACAGTATCGTCTGCACGGCCCAGGGTCCTGGGATAAAGCCAGGGATGCCATCACAAGCGCATGCGCCGATATCACTCCTGCTCGACCTAAGCATCAAGGACAAAGGAAAGGACTTTTAAGACGCTGTATTGCTGATGTAATAACATGTGTTGTGATCGATGTTGCTACGTCAATTGTTACACCAGTGTTTAGCTTTATCAGTGATCTGTTTTTTACGTGACAGTGGAGCTTCCTGTGGTACATTTTGATGAAGATCTATTTTTTACGGGAcacttgggcttcctgtggtacattttgataaagatctatttttttacgcgacagttgggcttcctgtggtacaTTTTGATAAAGATCTATTTTTACGTGAcacttgggcttcctgtggtacaTTGTGATAATGCACGTGAtttctagagtgcacgcactaaaagtgtgcaacgtaaataccactaaatagtgctatcagtttatgctaattctattgttttcttttatttaattatcgctatttactactaaataatgacaactgttgcacacatttagagtgcaaacaatttatccgtgaaactttagttaTACTAAATAGTACGATGTTATACAAATtctattgatttcttttgtttaattaacactattttgtactaaattgtaattagtgtttcacggatttattgtttgcactctagtgtttgcactctaaattTATCTTTGATTTTGACTATGTTTTTGTTGGCTCACCCTCATTAGAATGCACGTCGCATTAGTGTCTGGACCTGGAGAAATGCTAGAGTGTACGACACATTAACTtttagtgctagataagatttagtttaATACTCTCCCTTAGGGGGGCAAAATTGCTGAGGGTAAGCAATGGATGAGCAAGAATGCAAACGTTCAACTAGTGTTGTACAAACTGGCTAGAGAATCAATTGATTTAGTGTTCCATTCTGAAAATCCAAATATAACGTTCGCAGACTTTTTCAACTCTTCAATATTTAagatttacattttgtttaataatatCTTTACTgaaatttaatataatatgatgaatatatttttcttagaTTGGACatatcaaaaacataaaag

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8K4C0	Flavin-containing monooxygenase 5 OS=Rattus norvegicus OX=10116 GN=Fmo5 PE=1 SV=3
Q6IRI9	Dimethylaniline monooxygenase [N-oxide-forming] 2 OS=Rattus norvegicus OX=10116 GN=Fmo2 PE=2 SV=3
Q8K2I3	Dimethylaniline monooxygenase [N-oxide-forming] 2 OS=Mus musculus OX=10090 GN=Fmo2 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000875 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00743 all species →	FMO-like	Flavin-binding monooxygenase-like	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036188 all species →	Homologous_superfamily	FAD/NAD(P)-binding domain superfamily	Interproscan
IPR020946 all species →	Family	Flavin monooxygenase-like	Interproscan
IPR000960 all species →	Family	Flavin monooxygenase FMO	Interproscan
IPR002253 all species →	Family	Flavin monooxygenase (FMO) 1	Interproscan
IPR050346 all species →	Family	Flavin-containing Monooxygenases	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23023 all species →	DIMETHYLANILINE MONOOXYGENASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004499 all species →	Molecular Function	N,N-dimethylaniline monooxygenase activity	Interproscan
GO:0050660 all species →	Molecular Function	flavin adenine dinucleotide binding	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan
GO:0004497 all species →	Molecular Function	monooxygenase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00485	FMO; dimethylaniline monooxygenase (N-oxide forming) / hypotaurine monooxygenase	EC:1.14.13.8 EC:1.8.1.-	Drug metabolism - cytochrome P450	ko00982	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →