Gene detail

Detailed information of ENSDLIP00000029366.1 in Diadumene lineata

Genomic Location: not available for this species
NR annotation: XP_031555460.1, ADAM 17-like protease isoform X2 [Actinia tenebrosa]
Species abbreviation DLINE · all data for this species · gene families

Sequence

CDS

ENSDLIT00000032427

ATGACTGGTAGATCAGCTAAAAAAGTGATCATCTACTTATTTATGCTCCTGCTAGGATTTTCTAATGGTACTATCAGAGATATTTTAAAGGATTATAATACGTTAACAAAGACAGATATTCATCACTTGGTAACAAGACGAGATGCAGAAGGACAAGTTGAGAAagttatttcatttaaaacCCTTGGAAGAAAATTTCTCCTTCATCTGTCACCTAATGAAGGTCTTTTCTCTGAGAACTTTAACGCAGTAGTCGTCAGTGACGATAAAGAAGAGAATATTGTGATAGATAAACTGAGTTTTTACAGGGGATATGTTGAAGGTGAAGATCAATCCCAGGTCAGTGTTCATCTACAAGATGGAATGATGACAGCATCTATAGCAACATCCAATGAGACATATGTCATTGAGCCATCTTGGAGACATTTAGATCATCCTCGCCAAGAGGAGATGATTGCTTACAGACACTCTGACGTCAAGTTTAACTTTACTGATGGGCACACCAAAGATGGCAAAGGAAAAGTTAGTTTTTGTGGACATACGTCACCACCAACTGCAAACCAAAAATATGCTCAACAACAGAGTCATGACCATAGTCACAGAAGCCGCCGTGCTACAACACCAACAAAGCTGCGATGTCCACTAATGCTTGTTGCTGACTATAGATTCTTCCAGAAGATGGGTCAGTCAAATAAAGCCAACACTGTCAATTATATGATTGGTGTGATTGACCGAGTGGACAGAATCTACAAAACGACAACTTGGAGCATTGGATATGGAAATTATGGCTTTGAAATTGAGGAGGTAAAAGTACACCAAGCACCCACACGTACATCTGGTGTTGCACAACATTACAACCAAAAGAAAGACCTTTGGAATATCAAGGAACTACTAGAGGTGTTCAGCTATCAATCTGACTGGAAGAAGTACTGTTTGGCACATCTGTTTACCTATCAAGACTTTGCTGATGGAGTTATTGGATTGGCATATGTTGGTAATCCAAGACGGTCAGCTGTTGGTGGAATATGCACTGAAGATTACAAGACGGGTGGTCGTACGTTGTATTTGAACACTGGTTTAAGTAGTAGTGTTAACTGGGGAAGAAGAATCTTGACGGAGGAAGCAGACATTGTCACTGCTCATGAGTTTGGTCATAACTTTGGTAGTGAACACGATCCTGACAATGATGAGTGTGCTCCCAGTGAAAGAGATGGTGGAAAGTTTATCATGTATCCTGCATCAGTCAGTGGACAGAGGTCTAATAACAAGCTGTTTTCAGTTTGTAGTAGGAGACAGATTACATCAGTTTTAcagtcaaaatcaaaatactgCTTTACAGAACCAAGAGAAAAGATCTGTGGAAACTACAAGAAAGAATCAGGAGAGGAATGTGATCCTGGAAATTTAGGAACCATTGATTCAGCCTGTTGTACTAAAGACTGTAAATTGAAAGAGAATGCGCAATGCAGtgATGGCTATGACTCTCCCTGCTGCAAGAACTGCAAGTTTGCTACAGGAGAAGTATGTCGCAGAGCAGATGAAAACTCTTGTCAAGCCAAGACAGTTTGTAGAGGAAATAATCCACACTGTCCTGATGCCGACCCTCTGCCTGACAACACAACATGTATTGAAAGgGGTAAGTGTAGATCTGGTAAATGTGTAGAGTTCTGTGTAGCAGAGGGAATGCAGCCATGTTTGTGTGTGGACTCTCAGTATGCCTGCAAAGTATGTTGCAAGAAAATCAACTCTGAATGTCTACCATGGAAAAATGTGACTAGCGGTACAATGATTACCATGTTAGATGGACGACCATGTGCATCGGGCAGCTGTTTAaagGGAAAATGTGAGAAGATATCTCAAGATGTAGTGGAGAAGTTTTGGACATTTCTAACCAACCTGGATGTTAATGCATTTGTAGAGTTCATGAGAGCTAATATCGTTGgcactattttgtttttctctctgTGTATTTGGATTCCAGCAAGTTGTATTGTGCATAGAATTgaTAAGCGTAATGAAAAAGTAGAAGCTAAAGAACAGGAGTGGCGAGACCCTAAGAATACCCAGCTACTTCGTACTGTTCAGACAACCAAGAAAGGGGAATACATTTATCGTCAGGATTCCTTTGCCAGACCAAGCCAGCCAATGAAACCATTAAAACTAAGACCTGTATATGTCCGCACTCGCCAGAAACCACCACAGTTAGATGTTGCAACTGTCAATGAAGTCAGTGTTTAG

Transcript

ENSDLIT00000032427

GAACTCCAGTATTATTTTATGGTGGGTCTCTCTGTTATGGCTGGTCTGTACCTCTAAACTCCCTGTAAAAATGACTGGTAGATCAGCTAAAAAAGTGATCATCTACTTATTTATGCTCCTGCTAGGATTTTCTAATGGTACTATCAGAGATATTTTAAAGGATTATAATACGTTAACAAAGACAGATATTCATCACTTGGTAACAAGACGAGATGCAGAAGGACAAGTTGAGAAagttatttcatttaaaacCCTTGGAAGAAAATTTCTCCTTCATCTGTCACCTAATGAAGGTCTTTTCTCTGAGAACTTTAACGCAGTAGTCGTCAGTGACGATAAAGAAGAGAATATTGTGATAGATAAACTGAGTTTTTACAGGGGATATGTTGAAGGTGAAGATCAATCCCAGGTCAGTGTTCATCTACAAGATGGAATGATGACAGCATCTATAGCAACATCCAATGAGACATATGTCATTGAGCCATCTTGGAGACATTTAGATCATCCTCGCCAAGAGGAGATGATTGCTTACAGACACTCTGACGTCAAGTTTAACTTTACTGATGGGCACACCAAAGATGGCAAAGGAAAAGTTAGTTTTTGTGGACATACGTCACCACCAACTGCAAACCAAAAATATGCTCAACAACAGAGTCATGACCATAGTCACAGAAGCCGCCGTGCTACAACACCAACAAAGCTGCGATGTCCACTAATGCTTGTTGCTGACTATAGATTCTTCCAGAAGATGGGTCAGTCAAATAAAGCCAACACTGTCAATTATATGATTGGTGTGATTGACCGAGTGGACAGAATCTACAAAACGACAACTTGGAGCATTGGATATGGAAATTATGGCTTTGAAATTGAGGAGGTAAAAGTACACCAAGCACCCACACGTACATCTGGTGTTGCACAACATTACAACCAAAAGAAAGACCTTTGGAATATCAAGGAACTACTAGAGGTGTTCAGCTATCAATCTGACTGGAAGAAGTACTGTTTGGCACATCTGTTTACCTATCAAGACTTTGCTGATGGAGTTATTGGATTGGCATATGTTGGTAATCCAAGACGGTCAGCTGTTGGTGGAATATGCACTGAAGATTACAAGACGGGTGGTCGTACGTTGTATTTGAACACTGGTTTAAGTAGTAGTGTTAACTGGGGAAGAAGAATCTTGACGGAGGAAGCAGACATTGTCACTGCTCATGAGTTTGGTCATAACTTTGGTAGTGAACACGATCCTGACAATGATGAGTGTGCTCCCAGTGAAAGAGATGGTGGAAAGTTTATCATGTATCCTGCATCAGTCAGTGGACAGAGGTCTAATAACAAGCTGTTTTCAGTTTGTAGTAGGAGACAGATTACATCAGTTTTAcagtcaaaatcaaaatactgCTTTACAGAACCAAGAGAAAAGATCTGTGGAAACTACAAGAAAGAATCAGGAGAGGAATGTGATCCTGGAAATTTAGGAACCATTGATTCAGCCTGTTGTACTAAAGACTGTAAATTGAAAGAGAATGCGCAATGCAGtgATGGCTATGACTCTCCCTGCTGCAAGAACTGCAAGTTTGCTACAGGAGAAGTATGTCGCAGAGCAGATGAAAACTCTTGTCAAGCCAAGACAGTTTGTAGAGGAAATAATCCACACTGTCCTGATGCCGACCCTCTGCCTGACAACACAACATGTATTGAAAGgGGTAAGTGTAGATCTGGTAAATGTGTAGAGTTCTGTGTAGCAGAGGGAATGCAGCCATGTTTGTGTGTGGACTCTCAGTATGCCTGCAAAGTATGTTGCAAGAAAATCAACTCTGAATGTCTACCATGGAAAAATGTGACTAGCGGTACAATGATTACCATGTTAGATGGACGACCATGTGCATCGGGCAGCTGTTTAaagGGAAAATGTGAGAAGATATCTCAAGATGTAGTGGAGAAGTTTTGGACATTTCTAACCAACCTGGATGTTAATGCATTTGTAGAGTTCATGAGAGCTAATATCGTTGgcactattttgtttttctctctgTGTATTTGGATTCCAGCAAGTTGTATTGTGCATAGAATTgaTAAGCGTAATGAAAAAGTAGAAGCTAAAGAACAGGAGTGGCGAGACCCTAAGAATACCCAGCTACTTCGTACTGTTCAGACAACCAAGAAAGGGGAATACATTTATCGTCAGGATTCCTTTGCCAGACCAAGCCAGCCAATGAAACCATTAAAACTAAGACCTGTATATGTCCGCACTCGCCAGAAACCACCACAGTTAGATGTTGCAACTGTCAATGAAGTCAGTGTTTAGCTAAGGAATGGATGTCTTGCTCAAGCATTAGCATGTATCTGTTCAAAGGAACAAAATCTAAAAGTGTTGGTCATAGgaagaaattataaatataaaagatgaaaaaaaaaaactagctCTGCATGAATTTTAAGAtagcaatttattttattctagtATGTCGGGAATTTGATAGAAAATCTTACAAAATCTGGATATAGTGTGAATTTTATTGAGAGACAAGGAAATTAGTCCAAATCGTTTAAATTCTGTAAGAACTGACCGCCATGCATTTAGTTGTTGTTTAGTCAAGAAACAAGAATGCTATTTTAATATGTCCATCcagacaacattttttacaaatttgatgggcttcctgttttgaaAGAACAGAAGAGGGAGAGTGGTTAGAGATGGTACCCAAATAACTTGGCCATAGCAAAGGAATCCCAATGTTATGTGATATCAGAACTTGATCCAATAGAGTATCATATTAAACTCCAAATAGCTTGAATGTTGATGGCAGTTAGTTAAATGTATGTTAAGTGTTTTGCTTAAAGGTTTAATGGCACAATAGTATTGTATATAAAGTAAAATAGTTTCTTTTTCTAGATTGAAGTAtgaatgtattttgtattaaaaatgttaaataattattgaatgGAGGAGTTAAGCACAGTAAGTGTACTTGTTACTGCAAGTTTCCGTTATCTGCAAACTCAGACACAGAGATAATAGTGTTTCTTCTTCTGCACTCTTGCACTCACTACCTTGTTCTACATTTGTTTTGCAACTCATAAAATTGCTCactgttttgatgtttgtGGAGGAAGGAAAACCAGAGAGCttggagaaaaacccttgtggTATGAGAGAGGGAAACAACTATAAATGCTTACTACCAGTAGGCGTTTTTGCTCCCATCAATCAAACCTCTGATTgtgaaacaattaaaaactaaccaatcatgattcaaaTTTAAACATGAGTATAAGTTTAGACAAAATTCAGAGCCTTTTG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9VAC5	ADAM 17-like protease OS=Drosophila melanogaster OX=7227 GN=Tace PE=2 SV=2
P78536	Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ADAM17 PE=1 SV=1
Q9Z0F8	Disintegrin and metalloproteinase domain-containing protein 17 OS=Mus musculus OX=10090 GN=Adam17 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000695 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16698 all species →	ADAM17_MPD	Membrane-proximal domain, switch, for ADAM17	Domain	Interproscan
PF13574 all species →	Reprolysin_2	Metallo-peptidase family M12B Reprolysin-like	Domain	Interproscan
PF00200 all species →	Disintegrin	Disintegrin	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001762 all species →	Domain	Disintegrin domain	Interproscan
IPR051489 all species →	Family	Disintegrin and Metalloproteinase Domain-Containing	Interproscan
IPR036436 all species →	Homologous_superfamily	Disintegrin domain superfamily	Interproscan
IPR032029 all species →	Domain	ADAM17, membrane-proximal domain	Interproscan
IPR024079 all species →	Homologous_superfamily	Metallopeptidase, catalytic domain superfamily	Interproscan
IPR001590 all species →	Domain	Peptidase M12B, ADAM/reprolysin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45702 all species →	ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004222 all species →	Molecular Function	metalloendopeptidase activity	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006509 all species →	Biological Process	membrane protein ectodomain proteolysis	Interproscan
GO:0007219 all species →	Biological Process	Notch signaling pathway	Interproscan
GO:0008237 all species →	Molecular Function	metallopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K06059	ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17	EC:3.4.24.86	CD molecules	ko04090	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.