Genomic Location: chr9:12192217...12215490
NR annotation: XP_020894593.1, GATOR complex protein NPRL2 [Exaiptasia diaphana]
Species Diadumene lineata · all data for this species · gene families
| CDS |
| ENSDLIT00000033330 |
| Transcript |
| ENSDLIT00000033330 |
| Protein |
| ENSDLIP00000030129.1 |
| UniProt accession | Description |
|---|---|
| Q5E9U9 | GATOR1 complex protein NPRL2 OS=Bos taurus OX=9913 GN=NPRL2 PE=2 SV=1 |
| Q9WUE4 | GATOR1 complex protein NPRL2 OS=Mus musculus OX=10090 GN=Nprl2 PE=1 SV=1 |
| Q8WTW4 | GATOR1 complex protein NPRL2 OS=Homo sapiens OX=9606 GN=NPRL2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004011 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06218 all species → | NPR2 | Nitrogen permease regulator 2 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR009348 all species → | Family | Nitrogen permease regulator 2-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12991 all species → | NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005096 all species → | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005774 all species → | Cellular Component | vacuolar membrane | Interproscan |
| GO:0010508 all species → | Biological Process | positive regulation of autophagy | Interproscan |
| GO:0034198 all species → | Biological Process | cellular response to amino acid starvation | Interproscan |
| GO:1904262 all species → | Biological Process | negative regulation of TORC1 signaling | Interproscan |
| GO:1990130 all species → | Cellular Component | GATOR1 complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K20405 | NPRL2, NPR2; nitrogen permease regulator 2 | - | Membrane trafficking | ko04131 | deepkoala |
Genes whose expression across the transcriptome samples of Diadumene lineata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Diadumene lineata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |