Gene detail

Detailed information of ENSDTNP00000014222.1 in Metridium senile

Genomic Location: chr13:33016...37203
NR annotation: XP_020895543.1, E3 ubiquitin-protein ligase KCMF1 [Exaiptasia diaphana]
Species Metridium senile · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSDTNT00000014843

CTGTTGTCACCTCGGTCAGGAATCAGTCTGCCGTTCTTCTCCAAACCATGGATTTGTCAAGTTGTTAACAATTTCTCTTTGATTGTACGCAGCCAGAGTGATTCTGTTAACTAGAAATAACAAATGAGCTTCTTTCAGAGTTCAATTCAACGGTTTCTGGCGGTGAAAGAGGTTCAAATATTTTGTTCTGTGCTGTGCTATGTCTCGTCATGAAGGTGTTAGTTGCGACTCATGCAGTAAAGGGAATTTTAGAGGAAAAAGATTTAAATGTTTAATatgttatgattatgatttgtGCTCTACTTGCTATGAAAATGGAGCAACAACAACTAGACACACAGCTGAACACCCTATGCAATGTATCCTGACCAGGGCTGATTTTGatTTATATTATGGTGGAGAAGCGTTCACAGCTGATCAACCACAAGCATTTACTTGTCCTTATTGTAGTAAAATTGGTTTTACTGAAGCTCTTTTACAAGAACATGTAACATCAGATCACACAGATGCTTCCATGGAAGTTGTATGTCCTGTGTGTGCTGCATTACCTGGTGGTGATCCCAATCATGTAACCGATGACTTTGCTGCACATTTAACCTTAGAACACAGAGCTCCAAGGGACATTGATGAATCAGTGAGTGGGAGGCAAGTTAGACGGATGTTTCACCCAGGTCGTGGTGTGGGGGGTCCCAGACCTCCAAGACCTAGAACAGGAGCTATGAACTATAGCAGTTCCAACAGTGGTTCTTATGGCCCTTCCACAACATCAGCATCATCTGCTTCAAGTTTTCGAGAAAGTATGGATCCTATTGCTGAGCTGTTATCTCAGTTATCAGGTGTGCGAAGAGCTgcacaacaagcacaacccccAGTACAATCTCAGTTACAGTTactacagcaacaactacaactTGAACGACAGCAAGTCCAACAAACCAGAGAGAGACTGGAAAGACTTCCCCAAAGACGACAAGCAGCAGCTAACAATAACCAGGCAACTAGTACCACTTCaaatcaagataaaagtaattcTTCAAATTCACAGTTTTTATTATCCAGAGCCAATGAGCCAGCACTGTCAGACAGTGACCAGGAGGAGCTAGAAGTAGAAAGAGCTGATCGCTCActatttgttcaagatttaaTAGTTTCAAGTCTGGGCTCAATATCTATCAGAAGAGAGTCCAAACGCCAGGGAATAATGGAGGAATTGTTTTCGCTGCAAGGAAATGAACAAGGTGGTGCAATTGGAGGTGGAGATATCGCATGTCACAATAAACCAGATAGTATGCCAATATTAGAAAGAGAAGAGACTAACCAAGACATTGAAGTCATATCATTAGAAACACAAGATGACAAAGACTCCTAACAGCACTAGAGACACATATTGGATTGTTAAAATAAACTCTACCTGTAGCAGAAACAAACTGTTTTTACATAGAATGCAATGTTTGCTTGTAAACATTCAAGAACCATGTTGAACAAAggcaataattaataatttgtttatcttttgtgtatttgttttgttgataaatgaatgacatGATGATTACCTAAAGATGGTAATTTGTTGTACTTGTATCATAGTGAGATAAGGTATGTTGTATAAAAGATGATTGATACTTTTAACTGTTGCTAAGATATCAATGGATAGTAAAACTCCACAACTACTGAAACAAACCCTAACTttattcatcgttatcatagACATAGTGTTCAAACATGTATTTGACAGCAGCATCAAAATGACTCATGTTGACAGAAGTTTGTAGTATATTATGGCATACAATCATGTAATTGTCTTTTGATGTTTGTGCAAACAGTTGTCTGAGATGCTGGTGGATATCTATATGGTTAAAGTCAGCTTGAAAATAGATTTGATTTGATTCATTACTTGACAAATTACTAATGCTCTTCAATTCTTCAAGAAACAGTTTACGTTTAGCATTTTCTTCCTCAGCAAGGGTTTTCATCTGGTGTTTTGTGTATCCTCC

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9P0J7	E3 ubiquitin-protein ligase KCMF1 OS=Homo sapiens OX=9606 GN=KCMF1 PE=1 SV=2
Q80UY2	E3 ubiquitin-protein ligase KCMF1 OS=Mus musculus OX=10090 GN=Kcmf1 PE=1 SV=1
Q7T321	E3 ubiquitin-protein ligase KCMF1 OS=Danio rerio OX=7955 GN=kcmf1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004852 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00569 all species →	ZZ	Zinc finger, ZZ type	Domain	Interproscan
PF05605 all species →	zf-Di19	Drought induced 19 protein (Di19), zinc-binding	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000433 all species →	Domain	Zinc finger, ZZ-type	Interproscan
IPR008598 all species →	Domain	Drought induced 19 protein type, zinc-binding domain	Interproscan
IPR043145 all species →	Homologous_superfamily	Zinc finger, ZZ-type superfamily	Interproscan
IPR050774 all species →	Family	KCMF1 and Dystrophin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12268 all species →	E3 UBIQUITIN-PROTEIN LIGASE KCMF1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0099536 all species →	Biological Process	synaptic signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K22376	KCMF1, FIGC; E3 ubiquitin-protein ligase KCMF1	EC:2.3.2.27	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Metridium senile tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Metridium senile, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →