Gene detail

Detailed information of ENSDTNP00000023283.1 in Metridium senile

Genomic Location: :...
NR annotation: XP_028517085.1, folylpolyglutamate synthase, mitochondrial [Exaiptasia diaphana]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

ENSDTNT00000024339

CCGTGTAGACACGAGGATACGTGAAAATGGCCTCCTCAAAACCTGTTTAAAAGTCATGCTTTACATCATCAAACTTTGCTGCTTGGAGTCGTTTTAGAACCTCAGTGAAAGTACTATTGGATGGTTTACGGTCTGGTTGCCCGAGGCTTTCAAAATAGCCGTATTTTTGGCAGATTTTGTTCGCTTTCTGCAGCTATTAACATGGAGTCTCGTTCTTACGAAGATGCTATCAAAGCACTCAACAGTCTTCAGACTAATGCCCAGGTTCTGGCACAGATAAGAAAGACCCGGGGTAGACTGGCCCGAGATAACTTAGTTGACATGAAGATGTTCACGCAACGTGCTGGAGTAACCATGGAGATGCTTGACAAGCTGTCTGTTATTCACGTCAGTGGAACCAAGGGCAAGGGCTCAACGTGTGCCTTCACTGAGAGTATTCTACGACATGCTGGTTACACGACTGGCTTTTACAGTTCACCACATCTGATTGAAGTACGAGAAAGAATAAGACTGAACGGCAAACCTCTAAGCAAGGAACTGTTTACAAAATACTTCTTTCATTGTTGGGACAACCTTCAAGCTACACTGgATCAACATGAAGATAAGATGCCTGCTTACTTTAGGTTTATGACTCTTATGTCCTTCTATGTCTTCGTCAAAGAAAagGTTGATGTTGTTGTCTTAGAGGTTGGGCTTGGTGGAGCCTATGACTCTACTAACATTATAAGGAAGCCAGTTGTCTGTGGTGTTACATCGTTAGGAATGGATCACGTTGAAACACTGGGTGGTTCTCTGGAGAGCATTGCTTGGCAGAAAGCTGGCATCTTCAAGCCTGGTGTTCCAGCTTTCACCGTTGACCAAGAAGATAGTGCTTTACAAGTAGTGAAAGAGAGAGCAAGAGAAATCAATaaTCCCTTACAAGTTATCCCAAAGCTTGAAGCCTACCCAGGCTCAACACCAGtgtTGGGTTTGGACGGTAAACATCAACATGTGAACGCTTCATTGGCGTTACAGCTGACACACACATGGCTAGAGAATAGAACAAAAGTTAATAACAACAGTACCACCACTCCACTAGATGAAGCTCCACCAGCCAAGAAACCAAGACACCAATTCCAAGTAGCAGAGACGTTCGAGATAACAGAGGCAATCAGAGAAGGTTTAAGAAGTACTGTCTGGTTGGGAcgcaatcaaacaatcaaacgaCCAAACATCACCTTTTACCTTGATGGCGCCCACACGCCTAAAAGCATTGAGGCTTGCGTGGAGTGGTTTAAAGAGAAAGCAGATAAAGAAATGGCTGAAACAAATGGTTCTGTAAGTCGAGTTCTCTTGTTTAATCTTACTGGAGGAAGAGATCCACATGGGTTACTGCGTCCTTTAGTGAATCTCAAGTTTGACCATGCTGTATTCTCGCCAAATGCCGTCCAACTGGAACGAGTCGATAGTTCAGATTTATCCAACTTCACCGTGACGCGTGACAGTCAGTTACGCTGGTGTGTCGAGAACCAGCGTGTCTGGATGGCGTTACGCGGGGCTGGTTTCCAGGCCCACCCGACCTCGGATGAAGATCACGTGATCCAAAATGGTCACGATGATGGTCAATACTCAGCTATATTCCCTTGTGTTGCCCAGGCAACGCGGTGGATCGCGGCTGGCCGTGACCCATTAATTCCCACAATTAATAGCGCCGATCTAGAGCCACCGGAGTGTTTCGTAAAGTCAACCCATTTGCAAGTGCTGGTGGTTGGGAGTATTCATTTGGTAGGGTCGGTAATGAAAGTACTAGGGACAGAAGTTACTGGAGATATTTAGAATAtacttggacaacctttttggaataggtgtatgcctataattcctttccatcttggaatggcacatcgccttggacaacctttttggaataggtgtatgcctataattcctttccatcttggaatggcacatcgccttggacaacctttttggaataggtgtatgcctataattcctttccatcttggaatggcacatcgccttggacaacctttttggaataggtgtatgcctataattcctttccatcttggaatggcatatcgccttggacaacctttttgaaaattcATGACGTAGCTGAAGCTGCAGTCCACGCTCTGAAGCCTGCCAAGGATGTTGGTAGTATGAATATaaattttgatttgtttcatcatctaccgcTGCAACAACtttttatggtcatataacacaaacacgtacaaccaaaaaatgccatgaataaatcaatatcaAGAGAAGAGataccgaaatcctttgcaggcttcagagtgtggactgttgctTTGATTGTGACgacgatttttttaaattgatgtaaATTAAATTGTAGCTTCGTGCCGTACATTGCTTCTATcgccgctgtactatttaacaaaaggcgcatttgcacagactAAGCCGTCGATatattgtcaaaatattcacaaattccaagcaaagcacgaaaaaatgttatcgcttaacaatagaaaacacatctgaattgacttgaattgaggctatccctgtgcaaatacgcctttagtcaaattgtacagcggtgctagataacatgaaactggtctctTTGTGCGACTTATTGTATCGGGTcgatggtcacttaccagcatgctttgcgttgtgtattttgatttgagtgttataattcctTCGCAGTaggtcgtattacgagaaaacaaataaaacaaacactaaacgatttagtaaaagcataaatacccactcacagcgtaaaagatatcaaaatgatttgatttgagtactagtgttata

Protein

Uniprot

Uniprot term	Description
Q924L9	Folylpolyglutamate synthase, mitochondrial OS=Cricetulus griseus OX=10029 GN=FPGS PE=2 SV=1
Q05932	Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=FPGS PE=1 SV=3
A6H751	Folylpolyglutamate synthase, mitochondrial OS=Bos taurus OX=9913 GN=FPGS PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08245	Mur_ligase_M	Mur ligase middle domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036565	Homologous_superfamily	Mur-like, catalytic domain superfamily	Interproscan
IPR023600	Family	Folylpolyglutamate synthase, eukaryota	Interproscan
IPR036615	Homologous_superfamily	Mur ligase, C-terminal domain superfamily	Interproscan
IPR001645	Family	Folylpolyglutamate synthetase	Interproscan
IPR018109	Conserved_site	Folylpolyglutamate synthetase, conserved site	Interproscan
IPR013221	Domain	Mur ligase, central	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11136	FOLYLPOLYGLUTAMATE SYNTHASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005524	Molecular Function	ATP binding	Interproscan
GO:0009058	Biological Process	biosynthetic process	Interproscan
GO:0004326	Molecular Function	tetrahydrofolylpolyglutamate synthase activity	Interproscan
GO:0009396	Biological Process	folic acid-containing compound biosynthetic process	Interproscan
GO:0016881	Molecular Function	acid-amino acid ligase activity	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan
GO:0005739	Cellular Component	mitochondrion	Interproscan
GO:0005829	Cellular Component	cytosol	Interproscan
GO:0046901	Biological Process	tetrahydrofolylpolyglutamate biosynthetic process	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01930	FPGS; folylpolyglutamate synthase	EC:6.3.2.17	Antifolate resistance	ko01523	deepkoala