Genomic Location: :...
NR annotation: XP_029189471.2, protein patched homolog 1-like isoform X2 [Acropora millepora]
| CDS | |||||
| ENSEWQT00005034815 | |||||
| Transcript |
| ENSEWQT00005034815 |
| Protein |
| ENSEWQP00005024309.1 |
| Uniprot term | Description |
|---|---|
| Q98864 | Protein patched homolog 1 OS=Danio rerio OX=7955 GN=ptch1 PE=2 SV=1 |
| Q90693 | Protein patched homolog 1 OS=Gallus gallus OX=9031 GN=PTCH1 PE=1 SV=1 |
| Q13635 | Protein patched homolog 1 OS=Homo sapiens OX=9606 GN=PTCH1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12349 | Sterol-sensing | Sterol-sensing domain of SREBP cleavage-activation | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000731 | Domain | Sterol-sensing domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46022 | PROTEIN PATCHED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005119 | Molecular Function | smoothened binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0008158 | Molecular Function | hedgehog receptor activity | Interproscan |
| GO:0045879 | Biological Process | negative regulation of smoothened signaling pathway | Interproscan |
| GO:0097108 | Molecular Function | hedgehog family protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K06225 | PTCH1; patched 1 | - | Basal cell carcinoma | ko05217 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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