Gene detail

Detailed information of ENSIHXP00000022153.1 in Madracis auretenra

Genomic Location: not available for this species
NR annotation: KAJ7330171.1, hypothetical protein OS493_022690 [Desmophyllum pertusum]
Species Madracis auretenra · all data for this species · gene families

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q2KIH7	Phenylalanine-4-hydroxylase OS=Bos taurus OX=9913 GN=PAH PE=2 SV=1
P16331	Phenylalanine-4-hydroxylase OS=Mus musculus OX=10090 GN=Pah PE=1 SV=4
P04176	Phenylalanine-4-hydroxylase OS=Rattus norvegicus OX=10116 GN=Pah PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002500 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00351 all species →	Biopterin_H	Biopterin-dependent aromatic amino acid hydroxylase	Domain	Interproscan
PF01842 all species →	ACT	ACT domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR019774 all species →	Domain	Aromatic amino acid hydroxylase, C-terminal	Interproscan
IPR045865 all species →	Homologous_superfamily	ACT-like domain	Interproscan
IPR041912 all species →	Domain	Eukaryotic phenylalanine-4-hydroxylase, catalytic domain	Interproscan
IPR019773 all species →	Family	Tyrosine 3-monooxygenase-like	Interproscan
IPR036951 all species →	Homologous_superfamily	Aromatic amino acid hydroxylase superfamily	Interproscan
IPR036329 all species →	Homologous_superfamily	Aromatic amino acid monoxygenase, C-terminal domain superfamily	Interproscan
IPR002912 all species →	Domain	ACT domain	Interproscan
IPR018301 all species →	Binding_site	Aromatic amino acid hydroxylase, iron/copper binding site	Interproscan
IPR001273 all species →	Family	Aromatic amino acid hydroxylase	Interproscan
IPR005961 all species →	Family	Phenylalanine-4-hydroxylase, tetrameric form	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11473 all species →	AROMATIC AMINO ACID HYDROXYLASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016714 all species →	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	Interproscan
GO:0004497 all species →	Molecular Function	monooxygenase activity	Interproscan
GO:0005506 all species →	Molecular Function	iron ion binding	Interproscan
GO:0009072 all species →	Biological Process	aromatic amino acid metabolic process	Interproscan
GO:0004505 all species →	Molecular Function	phenylalanine 4-monooxygenase activity	Interproscan
GO:0006559 all species →	Biological Process	L-phenylalanine catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00500	phhA, PAH; phenylalanine-4-hydroxylase	EC:1.14.16.1	Folate biosynthesis	ko00790	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.