Gene detail

Detailed information of ENSIHXP00000028508.1 in Madracis auretenra

Genomic Location: not available for this species
NR annotation: XP_027041486.1, 3-hydroxyisobutyrate dehydrogenase, mitochondrial-like [Pocillopora damicornis]
Species Madracis auretenra · all data for this species · gene families

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q99L13	3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Hibadh PE=1 SV=1
P31937	3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBADH PE=1 SV=2
Q5R5E7	3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Pongo abelii OX=9601 GN=HIBADH PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004016 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03446 all species →	NAD_binding_2	NAD binding domain of 6-phosphogluconate dehydrogenase	Domain	Interproscan
PF14833 all species →	NAD_binding_11	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015815 all species →	Family	3-hydroxyisobutyrate dehydrogenase-related	Interproscan
IPR036291 all species →	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR002204 all species →	Conserved_site	3-hydroxyisobutyrate dehydrogenase-related, conserved site	Interproscan
IPR006115 all species →	Domain	6-phosphogluconate dehydrogenase, NADP-binding	Interproscan
IPR008927 all species →	Homologous_superfamily	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily	Interproscan
IPR011548 all species →	Family	3-hydroxyisobutyrate dehydrogenase	Interproscan
IPR013328 all species →	Homologous_superfamily	6-phosphogluconate dehydrogenase, domain 2	Interproscan
IPR029154 all species →	Domain	3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22981 all species →	3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan
GO:0008442 all species →	Molecular Function	3-hydroxyisobutyrate dehydrogenase activity	Interproscan
GO:0051287 all species →	Molecular Function	NAD binding	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0006574 all species →	Biological Process	valine catabolic process	Interproscan
GO:0016616 all species →	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00020	HIBADH, mmsB; 3-hydroxyisobutyrate dehydrogenase	EC:1.1.1.31	Valine, leucine and isoleucine degradation	ko00280	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.