Gene detail

Detailed information of ENSKFPP00000017569.1 in Condylactis gigantea

Genomic Location: chr2:9270514...9279121
NR annotation: XP_031552852.1, histone-lysine N-methyltransferase EZH2-like [Actinia tenebrosa]
Species Condylactis gigantea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSKFPT00000018924

ATGGAGACAGAATTCATGAAAATAGTTCGTCTGGAATATGTGAAGCTCCGTGAAAGCGCACAGCAGCAGAAAAAAGAATCATGCAAGAGAAACTTCACGGCGAACCGTCAAAAAATACGTGAACagttgaagaaaagaaagcaacTTAGCAAAGCTGTTGCATCTTGTCCTCTCGTTGCTACAACCATCTCTGCAGATCAAACACATGCTGGAGCTAAGAAGTGTAGTGCTGTCAGTGGCTTCAATCATCCAACCCAGCACACCTTACTGAGATCCATGCCATATGTCCATCCAATACCACAGTTCTTCACCTGGTCTCTCCTGCAACAAAACTTCATGGTAGAAGACGAGACCGTTTTACACAATATTCCATACATGGGTGAAGATGTTCTTGATCAAGATGGGTCATTCATAGAAGAACTGATCAAGAACTATGATGGAAAAGTACACAATGCACATGTGTTTGATGAGTACACCCTGACAGACAGTTTGCTGGTTGAACTGATTGACAATGTCATGAAAACtcttaaacaaaagaaatctgACAAGGATAGTGAAGGTAAAGAAATTGAAGAAGGTGCTACTCGAGAAACAACAACATCAGAAAGTAATGAGtctagaaaagacaagaaggaagagaaggaaaaaaagactgATGCCGCGGCTCCTCCTGATGAAGTTTTCCGGACCATTGTAAACCTGTTCCCAGAAAAATCCTGGACAGTCGAAGACATCAAAAATAGGTATTTTGAAGAAGTCAATCGCAAGAAGGGTCTTCTTCCTCCTGAGTGTACTCCAAACATTGACAGCTCAGAGGCTCAATCAGTATCCAGAGAGCAAAGCTTGCATTCCTTCCACATGTTGTTTTGCCGCCGATGCTACAAGTATGACTGCTTTATGCATGGATGGAAGCCCTTGCCAAACCTAGCAAAGCGAAAGagtcCTGTTGATCTGCCAGAATCATCTCCATGTGGAGCTGACTGCTACATGCATCTAAAGAGTACTACTGGCAGTCCTGTCAATTCACCTGGTAAATCTGAAATCACACCCAGGAAACGAAGTAGAGGCAAGAGTAAATCAGGCGCCCAGCAACCAGGTGGCTCGACCCCTGTGGCTAGTCCTTCCAAACCTGATTCTCGACCACTAGTGGATTCATCTGAATGGACTGGTGCTGAGTTGTCCCTTTTCCGTGTACTGCGAACTGTGTATTTCAATAATTACTGTACGATAGCCAATCTGATCGAAACCAAGAATTGCAAAGAGGTGTACCAACACGCACAAGTAGAACTAACCGAACCGCTTCCCGTGACAGATGACCAACACAGCACTCCACCCAGAAAACGAAAACGAAAGCACAGGATGTGGTCCCTTCATTGTCGCAAGATTCAACTTAAAAAAGACAGCACATCGACTCACGTGTACAACTACATCCCTTGTGACCATCCCGGCCAACCATGTGACCAAACATGCATCTGTGTGATGACGCAGAACTTCTGCGAGAAATTCTGCCAGTGTAATGTTGAGTGCCAGAATCGTTTCCCCGGCTGTCGCTGTAAGGCGCAATGTACCACCAAACAGTGTCCATGTTTCTTGGCCGTAAGGGAGTGTGATCCTGATCTCTGTTTTACTTGCGGTGCTGACAATTTCGAGGAAAACGCCGAGATCTGCTGCAAGAATGTCAGCCTTCAACGAGGACAGAGAAAGCATATGCTGTTAGCACCATCGGACGTGGCAGGATGGGGTATTTATATCAAGGAATCTTGTAAAAAGAACGATTTCATTGGGGAATATTGTGGAGAGGTTATTTCACAAGATGAAGCTGATCGGCGCGGCAAAGTTTACGATAAATACATGTGTAGTTTCTTGTTCAATCTCAATAATGACTTCGTGGTGGATGCTACTCGTAAAGGCAATAAGATCCGATTCGCAAACCATTCGATCAGTCCAAACTGCTATGCTAAAGTCATGATGGTTAATGGTGATCACCGCATTGGGATCTTTGCTAAACGGGACATCGAGAAAGGAGACGAGTTGTTCTTCGATTACCGATACAGCGCCACTGATGCTCTAAAGTTCGTGGGGATCGAACGAGATGTTGAGTTCGCTGTCCGATAA

Transcript

ENSKFPT00000018924

TAGCGAACCTTGGATAAGCAGAATCTTTTACTGAAATCAACGTAGCCGGCCCGACCAACATATAACCGAACTTATATCTCAAGTGGTATTGTGGTCGGCAGTCTTGAGAACGAATATGCGTATAATCTCTAATCTCTGGAGGATTTTTTGACAACCGATGAAATATCGAATGTTTATCGATTAGCAATCGATCGCGAAGTTCAATCGATCGAGTTCGAAGCACATGCTTTGTTGTTGTGCCGAAGACAAGAAAGCCAGCGAAGCGAATTTTCAGGATTTCCATTAGAAATTGTTCGAAAATGGAGACAGAATTCATGAAAATAGTTCGTCTGGAATATGTGAAGCTCCGTGAAAGCGCACAGCAGCAGAAAAAAGAATCATGCAAGAGAAACTTCACGGCGAACCGTCAAAAAATACGTGAACagttgaagaaaagaaagcaacTTAGCAAAGCTGTTGCATCTTGTCCTCTCGTTGCTACAACCATCTCTGCAGATCAAACACATGCTGGAGCTAAGAAGTGTAGTGCTGTCAGTGGCTTCAATCATCCAACCCAGCACACCTTACTGAGATCCATGCCATATGTCCATCCAATACCACAGTTCTTCACCTGGTCTCTCCTGCAACAAAACTTCATGGTAGAAGACGAGACCGTTTTACACAATATTCCATACATGGGTGAAGATGTTCTTGATCAAGATGGGTCATTCATAGAAGAACTGATCAAGAACTATGATGGAAAAGTACACAATGCACATGTGTTTGATGAGTACACCCTGACAGACAGTTTGCTGGTTGAACTGATTGACAATGTCATGAAAACtcttaaacaaaagaaatctgACAAGGATAGTGAAGGTAAAGAAATTGAAGAAGGTGCTACTCGAGAAACAACAACATCAGAAAGTAATGAGtctagaaaagacaagaaggaagagaaggaaaaaaagactgATGCCGCGGCTCCTCCTGATGAAGTTTTCCGGACCATTGTAAACCTGTTCCCAGAAAAATCCTGGACAGTCGAAGACATCAAAAATAGGTATTTTGAAGAAGTCAATCGCAAGAAGGGTCTTCTTCCTCCTGAGTGTACTCCAAACATTGACAGCTCAGAGGCTCAATCAGTATCCAGAGAGCAAAGCTTGCATTCCTTCCACATGTTGTTTTGCCGCCGATGCTACAAGTATGACTGCTTTATGCATGGATGGAAGCCCTTGCCAAACCTAGCAAAGCGAAAGagtcCTGTTGATCTGCCAGAATCATCTCCATGTGGAGCTGACTGCTACATGCATCTAAAGAGTACTACTGGCAGTCCTGTCAATTCACCTGGTAAATCTGAAATCACACCCAGGAAACGAAGTAGAGGCAAGAGTAAATCAGGCGCCCAGCAACCAGGTGGCTCGACCCCTGTGGCTAGTCCTTCCAAACCTGATTCTCGACCACTAGTGGATTCATCTGAATGGACTGGTGCTGAGTTGTCCCTTTTCCGTGTACTGCGAACTGTGTATTTCAATAATTACTGTACGATAGCCAATCTGATCGAAACCAAGAATTGCAAAGAGGTGTACCAACACGCACAAGTAGAACTAACCGAACCGCTTCCCGTGACAGATGACCAACACAGCACTCCACCCAGAAAACGAAAACGAAAGCACAGGATGTGGTCCCTTCATTGTCGCAAGATTCAACTTAAAAAAGACAGCACATCGACTCACGTGTACAACTACATCCCTTGTGACCATCCCGGCCAACCATGTGACCAAACATGCATCTGTGTGATGACGCAGAACTTCTGCGAGAAATTCTGCCAGTGTAATGTTGAGTGCCAGAATCGTTTCCCCGGCTGTCGCTGTAAGGCGCAATGTACCACCAAACAGTGTCCATGTTTCTTGGCCGTAAGGGAGTGTGATCCTGATCTCTGTTTTACTTGCGGTGCTGACAATTTCGAGGAAAACGCCGAGATCTGCTGCAAGAATGTCAGCCTTCAACGAGGACAGAGAAAGCATATGCTGTTAGCACCATCGGACGTGGCAGGATGGGGTATTTATATCAAGGAATCTTGTAAAAAGAACGATTTCATTGGGGAATATTGTGGAGAGGTTATTTCACAAGATGAAGCTGATCGGCGCGGCAAAGTTTACGATAAATACATGTGTAGTTTCTTGTTCAATCTCAATAATGACTTCGTGGTGGATGCTACTCGTAAAGGCAATAAGATCCGATTCGCAAACCATTCGATCAGTCCAAACTGCTATGCTAAAGTCATGATGGTTAATGGTGATCACCGCATTGGGATCTTTGCTAAACGGGACATCGAGAAAGGAGACGAGTTGTTCTTCGATTACCGATACAGCGCCACTGATGCTCTAAAGTTCGTGGGGATCGAACGAGATGTTGAGTTCGCTGTCCGATAACTAAAGCAcgcgtctgtctgtctgtctgccacTATCTGTCTGCGCATGACAGATAAATCCTCTAtctgtccgtccgtctgtctgtctgtgcCAGTCTTTGGTGGACGGTCATACAAATGTACCGCACACTCCCATCACTCGAGTTACACAGCGCTAACATATTCCCTGCGTATTGTAATGATTCTTTATCATCAAACTTTATTAAacattgattttcaaaaa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q4V863	Histone-lysine N-methyltransferase EZH2 OS=Xenopus laevis OX=8355 GN=ezh2-b PE=2 SV=1
Q61188	Histone-lysine N-methyltransferase EZH2 OS=Mus musculus OX=10090 GN=Ezh2 PE=1 SV=2
Q15910	Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004254 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00856 all species →	SET	SET domain	Family	Interproscan
PF18264 all species →	preSET_CXC	CXC domain	Domain	Interproscan
PF21358 all species →	Ezh2_MCSS	Ezh2, MCSS domain	Domain	Interproscan
PF18118 all species →	PRC2_HTH_1	Polycomb repressive complex 2 tri-helical domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001214 all species →	Domain	SET domain	Interproscan
IPR046341 all species →	Homologous_superfamily	SET domain superfamily	Interproscan
IPR041355 all species →	Domain	Pre-SET CXC domain	Interproscan
IPR033467 all species →	Domain	Tesmin/TSO1-like CXC domain	Interproscan
IPR048358 all species →	Domain	EZH1/2, MCSS domain	Interproscan
IPR026489 all species →	Domain	CXC domain	Interproscan
IPR041343 all species →	Domain	Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain	Interproscan
IPR045318 all species →	Family	Histone-lysine N-methyltransferase EZH1/2-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45747 all species →	HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0003682 all species →	Molecular Function	chromatin binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006338 all species →	Biological Process	chromatin remodeling	Interproscan
GO:0031507 all species →	Biological Process	heterochromatin formation	Interproscan
GO:0035098 all species →	Cellular Component	ESC/E(Z) complex	Interproscan
GO:0042054 all species →	Molecular Function	histone methyltransferase activity	Interproscan
GO:0046976 all species →	Molecular Function	histone H3K27 methyltransferase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11430	EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2	EC:2.1.1.356	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →