Gene detail

Detailed information of ENSKFPP00000022191.1 in Condylactis gigantea

Genomic Location: chr3:21429674...21441085
NR annotation: XP_031549168.1, phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta-like [Actinia tenebrosa]
Species Condylactis gigantea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSKFPT00000024038

ATGTTCCCAGTCGATGCGATGGAGTTGTTAAAGGTCAACTTCCCTGACTGCAAAGTGCGGGCAATGGCGGTCAAATGGATGGGGAACTTCAGCGATGATGAGCTGTGTGACTATCTACCACAGCTAGTCCAAGCACTAAAGTATGAGATTTATCACGATTCACCGCTGGCTCGGTTTCTTGTGCGGCGGGCGCTTGGGAACGTCAGGCTGATGCATATGCTGTTCTGGTATTTGAAGGACAAGATCAATGAACCTCAGTTTGGACAACGGTTTCAGGTCATCCTAGCGGGTCTACTTAACATTTGCGGCGAGGCACAAAGAGAGGAATTCACTTTTGAAGACGAACTCGTAGCCGAACTCGTTAAGGTTGCGCAGAAAGTGAAAAATGCTCGAGATTCAAGCCGCACAAGCATTCTTCAGCAGGAGCTGGCTGCATTAGCTGGCAGTCTTCCACGTGTATTCCGTCTGCCTTTGACCCCCAGCATGGAGGTGTCAGGGCTAGACGTCAAGTCCTGTGGTTACTTCACATCCAACTCTGCTCCCCTGAGGTTGACCTTCAAGAACACCGATGGTTTTGGTGAAAATGTCCATGTCATTTTCAAGATGGGAGATGACATGCGTCAAGACACGCTGACCATGCAGCTCGTGGGCATCATGAGTAAGATCTGGTTCCGTGAGGGCCTGGACTTGAAGATGATAACGTACCAGTGCATGGCGACGGGGCCTGGGATGGGGATGATTGAGATCGTCAGTGATGCACAGACTCTTCGTGAGATCCAAACCGAGTTTGGCCTGACAGGTTCCTTCAAGGACGAACCAATCGCCCGTTGGCTGCTCAAACACAACCCAGTGGAGAAGGACTACCGAATTGCAGTAGATAACTTCATCGCTTCATGCGCGGGCTACTGCGTCGCTACCTACGTACTGGGCATCTGTGATCGCCACAATGACAACATCATGATCAGAAAAAGCGGCCATCTTTTCCATATCGACTTTGCTAAGATCCTTGGGCATGCGCAAATGTTCGGTACGTTTCGCCGGGATCGTGCTCCCTTTGTCCTGACGTCAGATATGGCATACGTCATCAATGGTGGATACCAACCAAGCCCTCGATTCCAACACTTTGTTGATCTCTGCTGCAGGGCTTTCAATCTTGTTCGACGACATGCCAACCTGTTCTTGAATCTCTTGTCGCTGATGTTGAACTCCGGCATCCCATCCCTGAGCAGCGTGCACGATTTAAAGTACATCCGTGATTCCTTGATGCCCAATGCAAGCGATGCCGACGCAACGGCGGCATTCACTCGGCTAATCCATTCTAGTCTCTCCTCCACCTTCACGCAAGTGAACTTCTTCATCCACAATGTGGCACAAATCCGTGACGTCAGTCAGCTCAAGCGACCCAGTGCAGGCAACCCCAACTCTGTTCTTTCCTTCGCTCCTAAGACTCACAGTGCACACTTGGATGGGTACATAGACTCAGCCCGGGTGGTCGACATCCAGAAACGCCACATCCCTGGAGAAAAGTATTATATCTATGTCATCAACGTCTGCCGTGTGGCCGACACCAAGCCAACTTTTGTGTTTCGTCGCTTTGAGCACTTCCAAGAGCTGCACTCCAAACTCGCCGACGTATACCCCGAGGTTCACCTTCCTAGACTTCCTGCAAAGATTTTGCTCGGGAGGTCCCAGATTCGTACAGTCGCTGAGAAGAGAAGAGTGGAGTTGGATGATTACATCCAGCATCTCTTGATGATGCCCAGCGAGATCTCGGAGTCGGATGTTGTTTACACGTTCTTGCACTCCTTATTGATCGACGAAGAAGAGGCGTCCAAGTTTTCCATCCATTTGCTACCTGAAGAGAAAGCCACGAGGCCTATCACGGGACAGATCAAGCTTTCTTTGCGCTTCGAGCGAGATTCTCTTCGTGTGATGGTGATGCATGCGAAAGATTTGTCTCCACGCAGTCCAGGTGGCTCGGCGGATCCTTACGTCAAGTTATATCTGCTGCCAGACCCAGAGAAAGTCACCAAGATTAAAACCAAGATCGCAAAAAAGACTTTAAACCCCACGTACAATGAGACCCTAGTGTACAGTAACCGTCATAAAGCAGAACTCGAACGCCGTCAACTGCAAGTAACCGTGTGGGATCATGACAGGGTTGGTGAGAATGACTTCCTTGGCGGTGTCTTGATTGATCTTGCTAATGTGGACCTCAGCATTACTATCACTGGCTGGTACAACCTCTTGGATCTTAGGAAATAA

Transcript

ENSKFPT00000024038

CGTCTTTTAAACGTCTGGACGCCAATGTTCCCAGTCGATGCGATGGAGTTGTTAAAGGTCAACTTCCCTGACTGCAAAGTGCGGGCAATGGCGGTCAAATGGATGGGGAACTTCAGCGATGATGAGCTGTGTGACTATCTACCACAGCTAGTCCAAGCACTAAAGTATGAGATTTATCACGATTCACCGCTGGCTCGGTTTCTTGTGCGGCGGGCGCTTGGGAACGTCAGGCTGATGCATATGCTGTTCTGGTATTTGAAGGACAAGATCAATGAACCTCAGTTTGGACAACGGTTTCAGGTCATCCTAGCGGGTCTACTTAACATTTGCGGCGAGGCACAAAGAGAGGAATTCACTTTTGAAGACGAACTCGTAGCCGAACTCGTTAAGGTTGCGCAGAAAGTGAAAAATGCTCGAGATTCAAGCCGCACAAGCATTCTTCAGCAGGAGCTGGCTGCATTAGCTGGCAGTCTTCCACGTGTATTCCGTCTGCCTTTGACCCCCAGCATGGAGGTGTCAGGGCTAGACGTCAAGTCCTGTGGTTACTTCACATCCAACTCTGCTCCCCTGAGGTTGACCTTCAAGAACACCGATGGTTTTGGTGAAAATGTCCATGTCATTTTCAAGATGGGAGATGACATGCGTCAAGACACGCTGACCATGCAGCTCGTGGGCATCATGAGTAAGATCTGGTTCCGTGAGGGCCTGGACTTGAAGATGATAACGTACCAGTGCATGGCGACGGGGCCTGGGATGGGGATGATTGAGATCGTCAGTGATGCACAGACTCTTCGTGAGATCCAAACCGAGTTTGGCCTGACAGGTTCCTTCAAGGACGAACCAATCGCCCGTTGGCTGCTCAAACACAACCCAGTGGAGAAGGACTACCGAATTGCAGTAGATAACTTCATCGCTTCATGCGCGGGCTACTGCGTCGCTACCTACGTACTGGGCATCTGTGATCGCCACAATGACAACATCATGATCAGAAAAAGCGGCCATCTTTTCCATATCGACTTTGCTAAGATCCTTGGGCATGCGCAAATGTTCGGTACGTTTCGCCGGGATCGTGCTCCCTTTGTCCTGACGTCAGATATGGCATACGTCATCAATGGTGGATACCAACCAAGCCCTCGATTCCAACACTTTGTTGATCTCTGCTGCAGGGCTTTCAATCTTGTTCGACGACATGCCAACCTGTTCTTGAATCTCTTGTCGCTGATGTTGAACTCCGGCATCCCATCCCTGAGCAGCGTGCACGATTTAAAGTACATCCGTGATTCCTTGATGCCCAATGCAAGCGATGCCGACGCAACGGCGGCATTCACTCGGCTAATCCATTCTAGTCTCTCCTCCACCTTCACGCAAGTGAACTTCTTCATCCACAATGTGGCACAAATCCGTGACGTCAGTCAGCTCAAGCGACCCAGTGCAGGCAACCCCAACTCTGTTCTTTCCTTCGCTCCTAAGACTCACAGTGCACACTTGGATGGGTACATAGACTCAGCCCGGGTGGTCGACATCCAGAAACGCCACATCCCTGGAGAAAAGTATTATATCTATGTCATCAACGTCTGCCGTGTGGCCGACACCAAGCCAACTTTTGTGTTTCGTCGCTTTGAGCACTTCCAAGAGCTGCACTCCAAACTCGCCGACGTATACCCCGAGGTTCACCTTCCTAGACTTCCTGCAAAGATTTTGCTCGGGAGGTCCCAGATTCGTACAGTCGCTGAGAAGAGAAGAGTGGAGTTGGATGATTACATCCAGCATCTCTTGATGATGCCCAGCGAGATCTCGGAGTCGGATGTTGTTTACACGTTCTTGCACTCCTTATTGATCGACGAAGAAGAGGCGTCCAAGTTTTCCATCCATTTGCTACCTGAAGAGAAAGCCACGAGGCCTATCACGGGACAGATCAAGCTTTCTTTGCGCTTCGAGCGAGATTCTCTTCGTGTGATGGTGATGCATGCGAAAGATTTGTCTCCACGCAGTCCAGGTGGCTCGGCGGATCCTTACGTCAAGTTATATCTGCTGCCAGACCCAGAGAAAGTCACCAAGATTAAAACCAAGATCGCAAAAAAGACTTTAAACCCCACGTACAATGAGACCCTAGTGTACAGTAACCGTCATAAAGCAGAACTCGAACGCCGTCAACTGCAAGTAACCGTGTGGGATCATGACAGGGTTGGTGAGAATGACTTCCTTGGCGGTGTCTTGATTGATCTTGCTAATGTGGACCTCAGCATTACTATCACTGGCTGGTACAACCTCTTGGATCTTAGGAAATAAAATGCTTCAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O00750	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta OS=Homo sapiens OX=9606 GN=PIK3C2B PE=1 SV=2
Q61194	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Mus musculus OX=10090 GN=Pik3c2a PE=1 SV=2
O00443	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001304 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00454 all species →	PI3_PI4_kinase	Phosphatidylinositol 3- and 4-kinase	Family	Interproscan
PF00613 all species →	PI3Ka	Phosphoinositide 3-kinase family, accessory domain (PIK domain)	Repeat	Interproscan
PF00787 all species →	PX	PX domain	Domain	Interproscan
PF00168 all species →	C2	C2 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001683 all species →	Domain	Phox homology	Interproscan
IPR001263 all species →	Domain	Phosphoinositide 3-kinase, accessory (PIK) domain	Interproscan
IPR018936 all species →	Conserved_site	Phosphatidylinositol 3/4-kinase, conserved site	Interproscan
IPR036871 all species →	Homologous_superfamily	PX domain superfamily	Interproscan
IPR000403 all species →	Domain	Phosphatidylinositol 3-/4-kinase, catalytic domain	Interproscan
IPR036940 all species →	Homologous_superfamily	Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily	Interproscan
IPR015433 all species →	Family	Phosphatidylinositol kinase	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR042236 all species →	Homologous_superfamily	Phosphoinositide 3-kinase, accessory (PIK) domain superfamily	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR000008 all species →	Domain	C2 domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10048 all species →	PHOSPHATIDYLINOSITOL KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0035091 all species →	Molecular Function	phosphatidylinositol binding	Interproscan
GO:0016301 all species →	Molecular Function	kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0005942 all species →	Cellular Component	phosphatidylinositol 3-kinase complex	Interproscan
GO:0014065 all species →	Biological Process	obsolete phosphatidylinositol 3-kinase signaling	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016303 all species →	Molecular Function	1-phosphatidylinositol-3-kinase activity	Interproscan
GO:0016477 all species →	Biological Process	cell migration	Interproscan
GO:0035005 all species →	Molecular Function	1-phosphatidylinositol-4-phosphate 3-kinase activity	Interproscan
GO:0036092 all species →	Biological Process	phosphatidylinositol-3-phosphate biosynthetic process	Interproscan
GO:0046854 all species →	Biological Process	phosphatidylinositol phosphate biosynthetic process	Interproscan
GO:0048015 all species →	Biological Process	phosphatidylinositol-mediated signaling	Interproscan
GO:0052742 all species →	Molecular Function	phosphatidylinositol kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSKFPP00000022191.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →