Gene detail

Detailed information of ENSKFPP00000025565.1 in Condylactis gigantea

Genomic Location: chr4:10808345...10822920
NR annotation: XP_031556889.1, GATOR complex protein DEPDC5-like [Actinia tenebrosa]
Species Condylactis gigantea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSKFPT00000027799

ATGAAGCTTTTCAAGCTTTGGGTTCATCAGCATACGTTCAGTGAGGACGAATTGATAATCAATCCTAAAGAATTCCCTGATGGAAGCGTGGGGGATGTGTTGGAGATCTATCACCCTGAGGACCAAGGTTCAGCAAGGCTGTTGCTACAGATCAATTCGATCAGTGATTTCCAGCAGAAAGATACTGTTAGTATTGAACAGTCTGTTGCTAACTTGTTCCAGCTGCGAacttattcaaatgttaacgTGAAAAAggtaatttTTAGTGTAGACTTGGTCGACGTCCTGGTCAAAGATCAGTACCTCAGTAGGAGTGACATGTGGAGGTTGGCTAAGGCACTGGTTGGCAAGTGTGTCTATGTCTTTAAGAAACTCTCCTTCTCCGGAATCAGGGGGCAAATCAATGAACTGTGGACGAAGGGAACGCAGAAAACATGTGGAGTAATATCCAAGGATACAAAGGTGGTGTTTCGTTCATTGTCAGCGgaggtttttttcttcattcaaatGAGTCAAGAGATGTGGGACTTTGAGCTGAATGGGGACTTGTACTTTGAAAAAGTCATCAATGGATTTCTGCATGAATTATTTACTAAATGGAAAGAGCTGAAAACCAACCATGAAGTCTCGATTGTGCTCTTCTCCAGGACGTTTTATGACTGCATATCTGTAGATGCATTTCCTCCTGAGAAGCGAGGTAGCATCCTTCAAGATCCATATGGTCGATTCTATGAAGACTTCTATCAGGTCTTAGTCCATGAAGAGAGAAGAGATGACTGGCTACCAGTGTTAGTCAAGCTCAAATATCACTTCAATCAGTACCCAAAGTACATAAACTGCTGTCAAGATATCCCTGGAATGCCTTCCGGCAACAACTCTGGAGCTTTTGAGGGGAATTTCCTGGAAGCCATCAACCTAACAATGAACAtaTTTGAGAAGCATTATTTGGATCGTAATTTTGACAGAACAGGTCAAACTATCGTCATGGTTACCCCAGGCCCAGGGGTGTTTGAAGTGGACCGTGCACTGAACAGCATTACTAAACAGAGGATGGTTGATAGTGGTGTGGCAGTGGATTTAGTTTGCATGGCCGAGCAGCCACTGCATTCAGTACCTCTGTTAAAGTTCTACAATAAAGATGGCGATCGCAGGATCAGCATTGGTGATGATTACAACATCCCACACTGGATGAACCATAGCTTCTATACATCACACAAGGCCAAGAACAAACATGACTCCTTCCGACCTCGTATCAAGGTGCCGGATGTGGTGCTGAATCACTTTAACGTCAAGCCAGAAGAAAACCCTTACATGAAAGGTTTGCACAAGAATTTCCTTCCAAAGAACGCCAAAGACCAACTCGCCCATCAACTCCCAGATTTTATAAACTACGATGAATACGATGCCAATATATTTCGCGCCGGAAGTTCGGTTAAACAGAAAGCCAAGAACATTGAGCGCGGGAAATCCTCTCGGTCTGCGCCAAACTTCTCTAGACCTAACAGCTCGTCCGACTTCGAGAAACTGAGCAGGTCACGTGACGATGGGCATGTACTTCCCGATTACTCAACACGTGAATCGGTGCACAGTGCAATAGCCATACCATCATCTTCTATATCGGTGAGTAATATGATAGGCTTAATAATTGATTTtggattccttccttccttccttccttctttgcttgcttctttgcttccttTTGTTGTTGGTAGCGCAGGCGCGCCAAGACATTTCCCGGGTTTTCTTTCCCTCGTTACCCATGATCCTCGGCGAACGTTGTTCAATCCCTTCAAACCTCTGGATATACCCTGCAGATGGACCTGTAACCGCCATCGCTGGGCACATTGCTTCCCCAGAGGACCAGACGGGGAGAGTATTCATAGACACTTTGAAAAAccgaatgaaaagaaagaagatgacACCCCACAGAAGAAAAGTGGTTCAGTAGAAACACCGCTGTCGCCTGATCGCGGGCCATCGTCACGCAGACCACGTGTTCCGGCACGTACCAACTTCTTCCATCACTCTTCGGAGAAAGTGGAGCATGATTGGACAGCTGCTATAAAGaCTAGCGTTGACTGGGAGTCTCTGGTCCTACCAGCATGCCTCCCCCTGACCTCGGAGTACTGCCCAGATATGAAAACACTAGATACTGATTACTTGGAATTTCACTATGAACTGTGTGTTGGTGATGAGGAAGAGTATGCTGTAAGCAGGTTAAGATCTGCTAGCAATCCTGCAAGAATGGAGCATGAAAGCAGACACCCAGTATCTGTACAGTCAATGATCCTCGAGCTTGTAGCTCAAAGATTATCTAAGGGTTTTCAGATTCTAACTAACCCTCCTTATAACGAGAGGGGCCAATCATTCCCAGCATTCATTGCACAAGATGACGAATTTGAGTCTGAGGAATGTTTCTTGAGTCTTGGTCGTAACATCCACCGGCTGAGTGTGATACCCAACCAATCACAAATCAACGTCACGCGCTACCGACCTCGTCACGTCAGACGCGAGGTCAATCCTATAGAGTACAGGTATCGGCTGTGGGGAAGACATACCAAACAGTATTACTACAGAGAGGCAGAATTTCAACACGACGAACTGGATAAGTACAACTGGAACTATCTTGATCAACACATCAGTGGAGACCAAGACTTCACCGAACTGGTCGAGTCCCTCCGATACTGGAAAGCTCGTTTCCTGCTGCTCCCAGACACCAACTACAAGAGATACAACGtcgaagagaaagaaggagaCAGAAAAAACGCTAATGAGGAAGATTTTCGTATCGAAGGGATTCTGAAGTACCTTGAAATGTTGaatggaataaagcgaagcaAAGCTAGAAGAAGACCTTTCTCTCCCAATGTAAgtgaaggaaaaaatggaGTGGGTGAGACACCAGAGAGCACAGGAGATGACTCAACGGACGACTCACATGAAGGGACGTTGAACAAGACTTCACCACTAGAGTCCATTGCAGATGCCATAAATGGCTTTCCATTCCTCCCCTCTAGCAAGGGACTGGGTCACACTTGTTTTCTAAGCATCGAAGCGGTATGGTGGATGATGCATAATGTCAGAGGACTGGATGATAGGAAGGAGGCTGTTGTACTGGCACAGAAAATGGTTGATGCCAAGATATTCCAGCACGCCTCAGGAAGCAGTAGACACGAGTTCGTTTGTGGTTTCGCGATCTTCTGCATCACagccaaagaaaaatggaatgaaaaagaaggTAATGaccacgtgtcatttcctagtgaatatgattctttgtttaaggtgtatccatattcacgtgtcttctcatgctcaaccgttggacaaagaaatgatactctagggattgacacgtggtctgaaatgggagaaCATAACGCATCGAATAAGGTCTCTTGGCATACAAAGTGGTGGATATCACTTTGGCCGTTGAGAGGTTCAAACTACTCTTTTGATAATAACACTCTGTATTTTATGATTCTAGATTGTGGCTGTGGACCAGCTTACAAGACGGTCAACATCAACTGTGATGCACAACGAAAGAGTGAACGCCCTGAATGGGCAGTCATacgttaccatggcaactatTGTAATACGCATGCGTTCGAGATTGAAGTCCACTGGATAGAAACCACAGGCTCAGTGGTGAGCGATTTGATCCAAGGCTGGGCCCGGAAGGCCACCTCGTGTGGCTTCCATCTTATTCCAGTCCCCGTCAGTCCATTCCCAGACCCTGTTGGCTCCAGCTTCAACCCATTCAGACTCCCAGTGTACATCCCAGTTCTGCTGAGTTTTGGACCTTCGACGTTCCGAGTCCGAAAGTTTTTGTTCCTAGAAGCTATTCTTGAAAATTTTGGCTTCATTAAAGACTCTCCATATGGTTCAACCCACAACAGTTATTCGTTCGTTGCCCCTCCAGTCCAGTGCCGGGTTGCTGACTATGTCCACTCCTCTGGGGCTGCATTTGTACGTATACATGACCAGGACACCTCAGCCAAACCTGAAATCTATGGCGTTGGGTTCTTTTGGATGGAAAACTACATGTTGACGAAAAGATGGCGATCGGCAGCTACTGGAGATGTGGAGTTTGCGAGGAAGTTAATGACTGACTTTGAAGAGTTTTGTTCCAATAAGAATGGGACCCTAAAAGCATTCTGGGACGAATCGTGGGATTCTTTAATCAGGATCCACGGCGACGCATGGGTTCCAATCTGTTCTCTGCCATAA

Transcript

ENSKFPT00000027799

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P61460	GATOR1 complex protein DEPDC5 OS=Mus musculus OX=10090 GN=Depdc5 PE=1 SV=2
O75140	GATOR1 complex protein DEPDC5 OS=Homo sapiens OX=9606 GN=DEPDC5 PE=1 SV=2
Q9W0E3	GATOR complex protein Iml1 OS=Drosophila melanogaster OX=7227 GN=Iml1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003081 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12257 all species →	IML1	Vacuolar membrane-associated protein Iml1	Family	Interproscan
PF19418 all species →	DEPDC5_CTD	DEPDC5 protein C-terminal region	Family	Interproscan
PF00610 all species →	DEP	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036390 all species →	Homologous_superfamily	Winged helix DNA-binding domain superfamily	Interproscan
IPR048255 all species →	Domain	Vacuolar membrane-associated protein Iml1, N-terminal domain	Interproscan
IPR027244 all species →	Family	Vacuolar membrane-associated protein Iml1	Interproscan
IPR000591 all species →	Domain	DEP domain	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR045838 all species →	Domain	DEPDC5, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13179 all species →	DEP DOMAIN CONTAINING PROTEIN 5	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0005765 all species →	Cellular Component	lysosomal membrane	Interproscan
GO:0010508 all species →	Biological Process	positive regulation of autophagy	Interproscan
GO:0034198 all species →	Biological Process	cellular response to amino acid starvation	Interproscan
GO:1904262 all species →	Biological Process	negative regulation of TORC1 signaling	Interproscan
GO:1990130 all species →	Cellular Component	GATOR1 complex	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20404	DEPDC5, SEA1; SEA/GATOR complex protein SEA1/DEPDC5	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →