Gene detail

Detailed information of ENSKFPP00000025977.1 in Condylactis gigantea

Genomic Location: chr5:2660606...2667845
NR annotation: XP_031567617.1, importin subunit alpha-1-like isoform X1 [Actinia tenebrosa]
Species Condylactis gigantea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSKFPT00000028268

GGAAAGACTTGACTTCAAATTCCTTCGTCTCTTTACTCTTTGTCATTTAACTTTCTTCGCTGCAGACTTCAGTTAAAGAAGCTCCGATTTGTACATCTTTTGCTACAATATTCTAATATCCAAAGCCGTAAACATGGACGAAAATGCAGGCCGTATTCGTGCGTTTAAAAATAGGGGAAAAGACAACTCGGAGatgagaagaaggagaaatgATGTTACTATAGAATTACGAAAGGCCAAAAGAGATGACCAGGTTCTTAAGAGACGCAATCTCACTGAGATGGAAACTAGCCCCTTGAAAGAAGTCAATTCTCAACAGGTCATCCAGATATTGCCACTTCCCACAGTGTATCAGaACTTGCATACTGGTGATGACAATACTATATTCTTGAGCATTCAGTCAGTAAGGAAGATGCTTTCTAAAGAGAAGAATCCACCAGTAGATGAAGTAATCAAGGCTGGCCTTGTTCCATTTCTGGTTAAATTCCTGGAGCGGTTTGATTTTCCTCTGCTCCAGTTTGAAGCTGCCTGGGCTCTCACTAACATTGCTTCTGGAAACTCTGAGCAGACAAAGACTGTGGTTGACCATGGTGCTTTACCACTTTTCGTAAAGCTGCTTTCATCACCTCATGCCAATGTTTCCGAGCAAGCTGTATGGGCACTTGGCAACATTGCAGGTGACGGCCCGGTAATGCGCAATTCAGTCATTTCAACTGGTGCAATAGGACCACTTTTAGCACTCACTGCTAAACCCAATTCTGTCCAGTTTCTGCGTAACGTCACCTGGACATTATCCAACCTTTGTCGTAACAAGGACCCTCCTCCAGATGTCTCGGCTGTCAAACAGGTCTTGCCAACACTTGTTCAACTTCTTCACCATGATGACAAAGAGGTTCTAGCTGATACTTGTTGGGCTTTATCATACTTAACAGATGGGATCAATGACAGAATTCAGCTTGTGTTGGATTCAGGGGCTGTGCCACAACTTGTGAAACTGTTAGGTTACCCGGAGGTGAATGTGCTGACGCCAGCACTGAGGGCTGTTGGGAACATCGTTACTGGAAGAGATGATCAGACACAGGCAGTCATTGAAAGCAATGCATTGTTCTACTTTAGAAATCTTCTAACTCATAAACGAACCAGCATAGTCAAGGAATCAGCTTGGGCAATATCTAATATAACTGCAGgaacaaaacatcaaattcagtgTGTGATAGAAGCTGGTCTTATCCCTCTTGTTATTAGCATCCTAAAAAGAGTCAAAGGTGACttcaaagcaaagaaagaagctATCTGGGTCATCACTAACTATACTTCTGGTGCTACACCAGACCAACTCAAATACCTTTTACACTGTGATGTCATTCCACCAATGTGTGAACAGATGGAGCTCCTTGATCCAAAGGCTTTACTGATTCTCCTGGATGGCTTGAATAATATTTTCCATAATGCTGCCTCCATAGAGGAAGGAGCTGCTGAATTTGTTGCAGAAAAGTTTGAAGAGAGTGGCGGAATTGACATGCTTGAAAAACTACAAGAACATCCCAGACCTGAAGTATACCTAGCTAGTAAAACACTGATTGAGAAGTACTTCTCTGAGGGAGCTGAAGACGAAGACCCCAATCTTCAACCCGACAGTACCGAGGGGTACCACTTTGCACCCCCTCAAGAAGCTCCTGCCACAGGATTCCACTTTACCTAATAAGGATGACACATTATTATCCTATAATATGTTCTCTAAATACTGTAAATATTATTCTAAGAATACTGTGGTTTGATTCtcagaagagaaaaaacaagaCTTGATTATCAAATATTTGTAAGGTGGAAGTGGGCACTGAATATTTTTGTACAAAGTTATTGATAACTTTTGTGTGATAACATACTGTAGATGTGATGATCAAATGGTAGTTATGTTACATGGAATATGCATCAACTAGTGAATAACGAATAAATGGCCATACCTGTATGACAACAGACTTAGACAAAATAAATGACGATTGCTAATGAATATTTCCTGTCTTCTCACTTGTTGACATAGCCACTTCTGAAGACGTACTTGGGGTCAGCAGGTGACAAAACATCATGTGATGAACTTAAGAATGTCTGCTTTTTAAGGGATTAAGGTAGTCTCCTTTACAGCCACTGTGAGGCACACTTCCAGAACTGAAAGTGTGCCTCACagcggctgcgaaggaggcttaGGAGTTGGGggcaaaatttgaaattttggaAGAACATAAAAGTCCAGTCAAATGGAACATGCCATGTAATTTGATAGAACAAGGTACAGTAGATTGAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P52292	Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1
O35344	Importin subunit alpha-4 OS=Mus musculus OX=10090 GN=Kpna3 PE=1 SV=1
O00505	Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001131 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01749 all species →	IBB	Importin beta binding domain	Repeat	Interproscan
PF00514 all species →	Arm	Armadillo/beta-catenin-like repeat	Repeat	Interproscan
PF16186 all species →	Arm_3	Atypical Arm repeat	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002652 all species →	Domain	Importin-alpha, importin-beta-binding domain	Interproscan
IPR000225 all species →	Repeat	Armadillo	Interproscan
IPR024931 all species →	Family	Importin subunit alpha	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR036975 all species →	Homologous_superfamily	Importin-alpha, importin-beta-binding domain superfamily	Interproscan
IPR032413 all species →	Repeat	Atypical Arm repeat	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23316 all species →	IMPORTIN ALPHA	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006606 all species →	Biological Process	protein import into nucleus	Interproscan
GO:0061608 all species →	Molecular Function	nuclear import signal receptor activity	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006607 all species →	Biological Process	NLS-bearing protein import into nucleus	Interproscan
GO:0008139 all species →	Molecular Function	nuclear localization sequence binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K15043	KPNA2_7; importin subunit alpha-1/8	-	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Condylactis gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Condylactis gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →