Genomic Location: :...
NR annotation: XP_031549058.1, isoleucine--tRNA ligase, cytoplasmic-like [Actinia tenebrosa]
| CDS | |||||
| ENSKFPT00000030684 | |||||
| Transcript |
| ENSKFPT00000030684 |
| Protein |
| ENSKFPP00000028308.1 |
| Uniprot term | Description |
|---|---|
| P41252 | Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2 |
| Q8BU30 | Isoleucine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Iars1 PE=1 SV=2 |
| Q21926 | Isoleucine--tRNA ligase, cytoplasmic OS=Caenorhabditis elegans OX=6239 GN=iars-1 PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00133 | tRNA-synt_1 | tRNA synthetases class I (I, L, M and V) | Domain | Interproscan |
| PF19302 | DUF5915 | Domain of unknown function (DUF5915) | Domain | Interproscan |
| PF08264 | Anticodon_1 | Anticodon-binding domain of tRNA ligase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002300 | Domain | Aminoacyl-tRNA synthetase, class Ia | Interproscan |
| IPR023586 | Family | Isoleucine-tRNA ligase, type 2 | Interproscan |
| IPR002301 | Family | Isoleucine-tRNA ligase | Interproscan |
| IPR009008 | Homologous_superfamily | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain | Interproscan |
| IPR033709 | Domain | Isoleucyl tRNA synthetase type 2, anticodon-binding domain | Interproscan |
| IPR009080 | Homologous_superfamily | Aminoacyl-tRNA synthetase, class Ia, anticodon-binding | Interproscan |
| IPR014729 | Homologous_superfamily | Rossmann-like alpha/beta/alpha sandwich fold | Interproscan |
| IPR013155 | Domain | Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding | Interproscan |
| IPR001412 | Conserved_site | Aminoacyl-tRNA synthetase, class I, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42780 | SOLEUCYL-TRNA SYNTHETASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0004812 | Molecular Function | aminoacyl-tRNA ligase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006418 | Biological Process | tRNA aminoacylation for protein translation | Interproscan |
| GO:0004822 | Molecular Function | isoleucine-tRNA ligase activity | Interproscan |
| GO:0006428 | Biological Process | isoleucyl-tRNA aminoacylation | Interproscan |
| GO:0002161 | Molecular Function | aminoacyl-tRNA editing activity | Interproscan |
| GO:0000049 | Molecular Function | tRNA binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01870 | IARS, ileS; isoleucyl-tRNA synthetase | EC:6.1.1.5 | Transfer RNA biogenesis | ko03016 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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