Genomic Location: :...
NR annotation: XP_028514832.1, leucine--tRNA ligase, cytoplasmic isoform X1 [Exaiptasia diaphana]
| CDS | |||||
| ENSKFPT00000032374 | |||||
| Transcript |
| ENSKFPT00000032374 |
| Protein |
| ENSKFPP00000029871.1 |
| Uniprot term | Description |
|---|---|
| Q9P2J5 | Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2 |
| Q5R614 | Leucine--tRNA ligase, cytoplasmic OS=Pongo abelii OX=9601 GN=LARS1 PE=2 SV=1 |
| Q8BMJ2 | Leucine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Lars1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08264 | Anticodon_1 | Anticodon-binding domain of tRNA ligase | Domain | Interproscan |
| PF00133 | tRNA-synt_1 | tRNA synthetases class I (I, L, M and V) | Domain | Interproscan |
| PF09334 | tRNA-synt_1g | tRNA synthetases class I (M) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013155 | Domain | Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding | Interproscan |
| IPR002300 | Domain | Aminoacyl-tRNA synthetase, class Ia | Interproscan |
| IPR009008 | Homologous_superfamily | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain | Interproscan |
| IPR004493 | Family | Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic | Interproscan |
| IPR014729 | Homologous_superfamily | Rossmann-like alpha/beta/alpha sandwich fold | Interproscan |
| IPR015413 | Domain | Methionyl/Leucyl tRNA synthetase | Interproscan |
| IPR001412 | Conserved_site | Aminoacyl-tRNA synthetase, class I, conserved site | Interproscan |
| IPR009080 | Homologous_superfamily | Aminoacyl-tRNA synthetase, class Ia, anticodon-binding | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45794 | LEUCYL-TRNA SYNTHETASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004812 | Molecular Function | aminoacyl-tRNA ligase activity | Interproscan |
| GO:0006418 | Biological Process | tRNA aminoacylation for protein translation | Interproscan |
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0002161 | Molecular Function | aminoacyl-tRNA editing activity | Interproscan |
| GO:0004823 | Molecular Function | leucine-tRNA ligase activity | Interproscan |
| GO:0006429 | Biological Process | leucyl-tRNA aminoacylation | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01869 | LARS, leuS; leucyl-tRNA synthetase | EC:6.1.1.4 | Mitochondrial biogenesis | ko03029 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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